Covert antisocial behavior in boys with attention-deficit hyperactivity disorder: External validation and effects of methylphenidate.

Covert antisocial behaviors such as stealing, destroying property, and cheating carry high risk for delinquency. An individual laboratory setting was devised in which youngsters could take desired objects and use answer keys to assist with worksheets. 22 boys with attention-deficit hyperactivity disorder (ADHD) and 22 comparison boys were observed on 2 occasions, with the ADHD Ss receiving a methylphenidate–placebo crossover. Lab stealing and property destruction were positively correlated with maternal and staff ratings of parallel behaviors. Methylphenidate resulted in significant reductions of these acts, but it also effected an increase in cheating, presumably because of its enhancement of task involvement. The generalizability of the lab findings, actions of stimulants in this domain, and the ethics of experimental investigations of covert antisocial behavior are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Surface modification of a biocompatible polymer based on polyurethane for artificial blood vessels

An OH-functionalized poly(carbonate urethane) (PCU) is used for developing a new antithrombogenic surface. Biomolecules like glycine or the fibronectin fragment Gly-Arg-Gly-Asp-Ser (GRGDS) are covalently bound to the PCU surface by succinyl dichloride coupling. The modification steps are controlled by infrared spectroscopy and amino acid analysis. Successfully modified films are tested under stationary cell culture conditions.This paper was presented at thebiomat 90 Conference.     

Living carbocationic polymerization of isobutylene by tert-amyl alcohol/BCl3/1-methyl-2-pyrrolidinone initiating system

1-Methyl-2-pyrrolidinone has been investigated, for the first time, as an efficient electronpair donor in conjunction with tert-amyl alcohol and BCl₃ in CH₂Cl₂ diluent at ?40°C for the living polymerization of isobutylene. The use of this new monofunctional initiator -trans fer (minifer) system has led to the synthesis of low molecular weight, living (near-monodisperse) polyisobutylenes carrying “ethyl” head group and “tert-chloro” end group (asymmetric telechelic polyisobutylenes). The nature of these groups was confirmed by ¹H-NMR spectroscopy. The living nature of the α-ethyl-ω-(tert-chloro)polyisobutylenes has been demonstrated by a linear plot, passing through the origin, of number-average molecular weight (M?_n) vs. the amount of polymer formed (W_p) and a horizontal N (number of polyisobutylene molecules) vs. W_p plot. These results are further substantiated by gel permeation chromatography data of these polymers, and the molecular weight distributions of these polymers are narrow (low M?_w/M?_n = 1.1–1.2). The initiating efficiencies (I_eff) are close to 100% with this system. Dehydrochlorination of the prepolymer has yielded an isopropylidene (exo-olefin) end group. Structure of the end group in the resulting polymer, α-ethyl-ω-(isopropenyl)polyisobutylene, was confirmed by FTIR spectroscopy.     

Intralesional bleomycin-mediated electrochemotherapy in 20 patients with basal cell carcinoma

BACKGROUND: A new anticancer therapy, electrochemotherapy (ECT), has been introduced that entails exposing cancerous tissues to short pulses of electricity during chemotherapy. This enhances cell membrane permeability and has been shown to have potent antitumor effects in vitro in animal models and in several clinical trials, including nevoid basal cell carcinoma (BCC). OBJECTIVE: We report the effects of ECT on 20 patients with primary BCC. METHODS: Electrical pulses were delivered to 54 tumors after administration of intralesional bleomycin sulfate. RESULTS: Complete responses were observed in 53 (98%), and in the majority of these (94%) after a single treatment. No recurrences have been recorded with a mean of 18 months of observation. CONCLUSION: Although these are preliminary results, ECT appears to be an effective alternative to surgical excision for the treatment of primary BCC.     

Baselines for carbon emissions in the Indian and Chinese power sectors: Implications for international carbon trading

The study examines the dynamics of carbon emissions baselines of electricity generation in Indian states and Chinese provinces in the backdrop of ongoing electricity sector reforms in these countries. Two Indian states—Gujarat and Andhra Pradesh, and three Chinese provinces–Guangdong, Liaoning and Hubei have been chosen for detailed analysis to bring out regional variations that are not captured in aggregate country studies. The study finds that fuel mix is the main driver behind the trends exhibited by the carbon baselines in these five cases. The cases confirm that opportunities exist in the Indian and Chinese electricity sectors to lower carbon intensity mainly in the substitution of other fuels for coal and, to a lesser extent, adoption of more efficient and advanced coal-fired generation technology. Overall, the findings suggest that the electricity sectors in India and China are becoming friendlier to the global environment. Disaggregated analysis, detailed and careful industry analysis is essential to establishing a power sector carbon emissions baseline as a reference for CDM crediting. However, considering all the difficulties associated with the baseline issue, our case studies demonstrate that there is merit in examining alternate approaches that rely on more aggregated baselines.     

各种添加剂对卷烟烟气组成的影响综述(Ⅰ)

以表格的形式简要地介绍了各种烟草添加剂的添加量、添加位置、添加方法、是否转移到主流烟气中、热解产物及其对主流烟气的影响     

Real-time PCR detection of the thermostable direct hemolysin and thermolabile hemolysin genes in a Vibrio parahaemolyticus cultured from mussels and mussel homogenate associated with a foodborne outbreak

Molecular methods have become vital epidemiological tools in the detection and characterization of bacteria associated with a foodborne outbreak. We used both culture and real-time PCR to detect a Vibrio parahaemolyticus isolate associated with a foodborne outbreak. The outbreak occurred in July 2002 in Polk County, Florida, and originated at a Chinese buffet, with one person being hospitalized. The hospital isolated V. parahaemolyticus from the patient but destroyed the sample after diagnosis. From an onsite visit of the restaurant, food samples that possibly contributed to the outbreak were collected and sent to the Florida Department of Health, Tampa Branch Laboratory. Crab legs, crabsticks, and mussel samples were homogenized and incubated according to the Food and Drug Administration Bacteriological Analytical Manual culture protocol. Three sets of primers and a TaqMan probe were designed to target the tdh, trh, and tlh genes and used for real-time PCR. This study was successful in isolating V. parahaemolyticus from a mussel sample and detecting two of its genes (tdh and tlh) in food and pure culture by real-time PCR.