Dynamics of Strong Coupling between J‐Aggregates and Surface Plasmon Polaritons in Subwavelength Hole Arrays

A prototypical hybrid system formed by strong coupled gold hole arrays and J‐aggregate molecules is investigated by using both steady‐state spectroscopic method and ultrafast pump‐probe approach. In particular, the plasmonic response of the device has been tuned by modifying its periodicity thus to achieve the strongest possible coupling regime. It is found that in the transient absorption spectra, under upper band excitation, the bleaching signal from uncoupled J‐aggregate molecules completely disappears. Instead, two distinctive period dependent bleaching bands are formed, clearly fingerprint of the hybrid exciton‐plasmon state. The dynamics of these bands is also directly analyzed. A remarkable long lifetime is found especially for the upper band, corresponding to the presence of a trap state in its transient absorption spectra under resonance excitation. Such unique feature should provide a new approach to control quantum‐mechanical states under coherent coupling.     

Integrated Obstacle Avoidance and Path Following Through a Feedback Control Law

The article proposes a novel approach to path following in the presence of obstacles with unique characteristics. First, the approach proposes an integrated method for obstacle avoidance and path following based on a single feedback control law, which produces commands to actuators directly executable by a robot with unicycle kinematics. Second, the approach offers a new solution to the well–known dilemma that one has to face when dealing with multiple sensor readings, i.e., whether it is better, to summarize a huge amount of sensor data, to consider only the closest sensor reading, to consider all sensor readings separately to compute the resulting force vector, or to build a local map. The approach requires very little memory and computational resources, thus being implementable even on simpler robots moving in unknown environments.     

Filler materials: The current situation and future trends with particular reference to lead‐free soldering alloys

Summary

Over the past five years, the electronic assembly industry has been examining a variety of alloy systems as lead‐free alternatives to the conventional 63Sn/37Pb eutectic system. Many of the proposed systems are quite interesting from a technical standpoint but fall short when considering practical issues such as cost, availability and repeatability of manufacture.

The purpose of this paper is to provide the industry with a practical and technically feasible, lead‐free process which can be implemented or used as a baseline to compare other more complex systems.     

Alloantigen presenting capacity, T cell alloreactivity and NK function of G-CSF-mobilized peripheral blood cells

In this study we addressed whether the proportion and the function of antigen presenting cells (APC), T and NK lymphocytes are modified in the apheresis product of six healthy donors who received a stem cell mobilizing treatment with glycosylated G-CSF at 10 microg/kg/day x 5 days s.c. Flow cytometry analysis showed comparable percentages of HLA-DR+, CD19+, CD86+, CD80+ and CD1a+ cells in preG-CSF-peripheral blood mononuclear cells (preG-PBMC) and after mobilization in G-PBMC, whereas the proportion of CD14+ monocytes significantly increased in G-PBMC (3+/-1% vs 17+/-8%, P = 0.003). Analysis of lymphocyte subsets in preG-PBMC and G-PBMC showed similar proportions of CD3+, CD4+, CD8+ and CD28+ T cells, but a significantly lower percentage of CD16+ (11+/-7% vs 4+/-1%, P=0.01), CD56+ (15+/-6% vs 5+/-2%, P= 0.008), CD57+ (16+/-9% vs 5+/-2%, P=0.04), CD25+ (19+/-2% vs 9+/-6%, p=0.009) and CD122+ (5+/-2% vs 2+/-1%, P = 0.05) cells in G-PBMC. Unfractionated preG-PBMC and G-PBMC were irradiated and tested in primary mixed leukocyte culture (MLC) with two HLA-incompatible responders and induced efficient alloresponses in four of six cases, whereas G-PBMC stimulated poorly in the remaining two cases. Also, in allo-MLC with irradiated G-PBMC we detected lower amounts of IFN-gamma (P = 0.04) and of IL-2 (P = 0.06) than in allo-MLC with preG-PBMC. Furthermore, freshly isolated preG-PBMC and G-PBMC from each donor exerted comparable allogeneic responses to HLA-incompatible irradiated mononuclear cells in all cases. However, G-PBMC showed no NK activity against K562 target cells at any effector:target ratio tested. These data suggest that normal G-PBMC may prevent Thl alloresponses, maintain efficient alloreactivity to HLA mismatched antigens and have impaired NK activity.     

Low-power data forwarding for VLIW embedded architectures

Proposes a low-power approach to the design of embedded very long instruction word (VLIW) processor architectures based on the forwarding (or bypassing) hardware, which provides operands from interstage pipeline registers directly to the inputs of the function units. The power optimization technique exploits the forwarding paths to avoid the power cost of writing/reading short-lived variables to/from the register file (RF). Such optimization is justified by the fact that, in application-specific embedded systems, a significant number of variables are short-lived, that is, their liveness (from first definition to last use) spans only few instructions. Values of short-lived variables can thus be accessed directly through the forwarding registers, avoiding writeback to the RF by the producer instruction and successive read from the RF by the consumer instruction. The decision concerning the enabling of the RF writeback phase is taken at compile time by the compiler static scheduling algorithm. This approach implies a minimal overhead on the complexity of the processor control logic and, thus, no critical path increase. The application of the proposed solution to a VLIW embedded core has shown an average RF power saving of 7.8% with respect to the unoptimized approach on the given set of target benchmarks.     

Disassembly of the cholinergic postsynaptic apparatus induced by axotomy in mouse sympathetic neurons: the loss of dystrophin and beta-dystroglycan immunoreactivity precedes that of the acetylcholine receptor

In mouse sympathetic superior cervical ganglion (SCG), cortical cytoskeletal proteins such as dystrophin (Dys) and beta1sigma2 spectrin colocalize with beta-dystroglycan (beta-DG), a transmembrane dystrophin-associated protein, and the acetylcholine receptor (AChR) at the postsynaptic specialization. The function of the dystrophin-dystroglycan complex in the organization of the neuronal cholinergic postsynaptic apparatus was studied following changes in the immunoreactivity of these proteins during the disassembly and subsequent reassembly of the postsynaptic specializations induced by axotomy of the ganglionic neurons. After axotomy, a decrease in the number of intraganglionic synapses was observed (t1/2 8 h 45'), preceded by a rapid decline of postsynaptic specializations immunopositive for beta-DG, Dys, and alpha3 AChR subunit (alpha3AChR) (t1/2 3 h 45', 4 h 30' and 6 h, respectively). In contrast, the percentage of postsynaptic densities immunopositive for beta1sigma2 spectrin remained unaltered. When the axotomized neurons began to regenerate their axons, the number of intraganglionic synapses increased, as did that of postsynaptic specializations immunopositive for beta-DG, Dys, and alpha3AChR. The latter number increased more slowly than that of Dys and beta-DG. These observations suggest that in SCG neurons, the dystrophin-dystroglycan complex might play a role in the assembly-disassembly of the postsynaptic apparatus, and is probably involved in the stabilization of AChR clusters.