Scanning electron microscope (SEM) disclosure of the effects of snake venom on living tissue integrity and cell surfaces

The tissue destruction produced by the bite of the viper is well known and the venom enzyme[s] that produce it have been thoroughly studied. Not so well examined is the view of the damage available to the electron microscope, especially the scanning electron microscope. Here we have used the SEM to view the effects of viper venom on living tissue in situ. SCANNING 32: 155–158, 2010. © 2010 Wiley Periodicals, Inc.     

Characterization, modeling and assessment of Roll-N-Cage isolator using the cable-stayed bridge benchmark

This paper presents the results of an extensive series of simulation tests to identify the mechanical characteristics of an innovative isolation device known as the Roll-N-Cage (RNC) isolator. The seismic performance of an RNC passive control scheme is subsequently investigated on a model of the cable-stayed bridge benchmark. Starting from different configurations studied in the laboratory for a 1/10 reduced-scale prototype, the RNC isolator stiffness and damping properties are investigated in terms of cyclic tests with different parameters. Tests at the ultimate level state consisting of monotonic shear and axial loading have been also carried out as a part of the qualification process. The goal of this study is twofold: first, to examine the main integrated mechanisms of the RNC isolator through sophisticated 3D finite element simulation models using a multi-purpose finite element code. The main result of this step is to attempt modeling the force–displacement relationship using the standard Bouc–Wen model of smooth hysteresis. The second aim of this study is the numerical assessment of the device efficiency through its implementation into a bridge model considering several ground motions as external excitations. Based on these extensive studies, it was found that the RNC isolator is promising as a reliable isotropic horizontal isolation device for bridge structures.     

使简单欧姆计具备千兆欧量程的积分器

德州仪器公司(TI)的IVC102精密积分器有高质量的内部电容.图1的电路可以用来测量非常高的Rx电阻值.一只精密差分放大器(TI的INA105)为Rx施加一个基准电压.积分期间,在IVC12的输出端产生一个负电压斜坡Vo.两只LM311将Vo的振幅与两个固定阈值作比较,产生两个数字信号:开始和停止.     

Paillier''s Trapdoor Function Hides up to O ( n ) Bits

At EuroCrypt '99 Paillier proposed a new encryption scheme based on higher residuosity classes. The new scheme was proven to be one-way under the assumption that computing N -residuosity classes in Z _N2 ^* is hard. Similarly the scheme can be proven to be semantically secure under a much stronger decisional assumption: given w ∈ Z _N2 ^* it is impossible to decide if w is an N -residue or not. In this paper we examine the bit security of Paillier's scheme. We prove that if computing residuosity classes is hard, then given a random w it is impossible to predict the least significant bit of its class significantly better than at random. This immediately yields a way to obtain semantic security without relying on the decisional assumption (at the cost of several invocations of Paillier's original function). In order to improve efficiency we then turn to the problem of simultaneous security of many bits. We prove that Paillier's scheme hides n-b (up to O(n) ) bits if one assumes that computing the class c of a random w remains hard even when we are told that c<2 ^b . We thoroughly examine the security of this stronger version of the intractability of the class problem. An important theoretical implication of our result is the construction of the first trapdoor function that hides super-logarithmically (up to O(n) ) many bits. We generalize our techniques to provide sufficient conditions for a trapdoor function to have this property.     

Assessing the usability of a visual tool for the definition of e-learning processes

In this paper, we present a usability study aiming at assessing a visual language-based tool for developing adaptive e-learning processes. The tool implements the adaptive self-consistent learning object SET (ASCLO-S) visual language, a special case of flow diagrams, to be used by instructional designers to define classes of learners through stereotypes and to specify the more suited adaptive learning process for each class of learners. The usability study is based on the combined use of two techniques: a questionnaire-based survey and an empirical analysis. The survey has been used to achieve feedbacks from the subjects’ point of view. In particular, it has been useful to capture the perceived usability of the subjects. The outcomes show that both the proposed visual notation and the system prototype are suitable for instructional designers with or without experience on the computer usage and on tools for defining e-learning processes. This result is further confirmed by the empirical analysis we carried out by analysing the correlation between the effort to develop adaptive e-learning processes and some measures suitable defined for those processes. Indeed, the empirical analysis revealed that the effort required to model e-learning processes is not influenced by the experience of the instructional designer with the use of e-learning tools, but it only depends on the size of the developed process.     

Specificity of substrate recognition by Pseudomonas fluorescens N3 dioxygenase. The role of the oxidation potential and molecular geometry

Pseudomonas fluorescens N3 is able to grow on naphthalene as the sole carbon and energy source. The mutant TTC1, blocked at the dihydrodiol dehydrogenase level, which can transform the hydrocarbon into the corresponding dihydrodiol, has been used to produce bioconversion products. To rationalize the different grades of conversion obtained with different substrates, a study was performed using non-naphthalene derivatives, including benzenes, conjugated benzenes, and polycyclic aromatic hydrocarbons. The corresponding diols obtained by bioconversion have been isolated and characterized. A theoretical model that considers both energy and geometry factors has been proposed to rationalize the experimental data. Good agreement has been found between the calculated values and the experimental results.     

Comparative ion-exchange characterization of zeolitic and clayey materials for pedotechnical applications—Part 2: interaction with nutrient cations

With the purpose to evaluate the possible use of a phillipsite-rich tuff, in place of the naturally occurring clay minerals, as inorganic ion-exchanger component of organo-mineral aggregates of pedotechnical interest, the ion-exchange behavior of Neapolitan yellow tuff and a reference montmorillonite-rich material towards some nutrient cations was investigated. Accordingly, exchange kinetics and isotherms of Na⁺, K⁺, and NH₄ ⁺ for Ca²⁺, at 25 °C and 0.1 total normality, were determined, and the related kinetic and thermodynamic quantities computed. The obtained results point out that the zeolitic material, apart from a higher cation exchange capability, exhibits selectivity performances towards nutrient cations comparable or even better than those of the montmorillonitic material, confirming, on the basis of the previous data concerning noxious cations, that phillipsite-rich tuffs can be considered potential substitutes of clay materials to recover and/or rebuild polluted and degraded soils.     

A spectro-microscopic investigation of Fe-Co bimetallic catalysts supported on MgO for the production of thin carbon nanotubes

Fe-Co bimetallic catalysts supported on MgO were studied for the catalytic chemical vapor deposition growth of carbon nanotubes (CNTs). Different wt.% metal loadings were investigated at various deposition temperatures and times. Characterization of the products involved thermal analysis (DTA-TGA), X-ray diffraction, spectroscopy (Raman, UPS, EELS and STS) and microscopy (SEM, TEM and STM) techniques. It was found that the metal content is critical, not only to the yield and the structural quality of the synthesized carbon nanotubes, but it can be also used to tune the desired type of synthesized nanotubes. Lower (2 wt.%) loadings of Fe-Co catalysts favor the formation of single- and/or double-wall CNTs for deposition time and temperature 30 min and 800 °C, respectively. Thermal analysis and Raman measurements showed that these thin CNTs were synthesized at high amounts (CNT-per-catalyst wt.% of more than 100%), exhibiting high graphitization degree with only traces of by-products (mainly amorphous carbon) among them. Microscopy results revealed the formation of CNTs bundles, consisting of individual nanotubes with less than 2 nm outer diameter, while additional energy loss measurements pointed out that the deposited CNTs are mainly single wall. Higher (10 wt.%) Fe-Co loadings resulted to the formation of multi-wall CNTs.