宫颈癌S—100^＋Langerhans细胞的检测

Langerhans cells (LC) in the normal cervix (control, 19 cases) and cervical carcinoma in situ (CIS, 19 cases), interdigitating cells (IDC) and follicular dendritic cells (FDC) in obturator lymph node draining infiltrating cervical carcinoma (30 cases) were quantitatively assayed by ABC immunohistochemical method using anti-S-100 protein antibody. The results indicated that S-100+ LC in situ, S-100+ IDC and S-100+ FDC in obturator lymph node showed dendritic features with a specific distribution. The number of LC in situ in infiltrating carcinoma increased significantly as compared with CIS and control groups. There was no change in LC number between Grades II and III of squamous cell carcinoma. The number of IDC was significantly less in Stage II than in Stage I lesion. FDC number in different depths of invasion and clinical stages showed no obvious change. The results suggest that progression of cervical carcinoma is closely related to decrease in LC in situ and IDC in regional lymph node. Predominant immune response of the host to cervical carcinoma should be cellular immune.     

口服强的松和灭吐灵对控制化疗所致恶心呕吐的作用

细胞抑制剂顺铂的应用使某些类型的恶性肿瘤的治愈及姑息效果得到很大的改善,但是严重的恶心及长时间的呕吐使病人甚感烦恼,对医生及护士的情绪也大受影响。曾有多篇报道恶心在12小时以上及呕吐的中数次数在14次以上者用通常剂量的镇吐药物难以控制。近两年用大剂量静脉注射地塞米松或甲基强的松使恶心呕吐明显解除,大剂量灭吐灵也有同样效果。在随机化安慰剂的对照试验下,这些效果也是肯定的。但每隔2～4小时静脉注射一次对工作人     

宫颈管诊刮对导常富颈细胞论片病人的价值

对异常宫颈涂片的患者应行阴道镜检查。适宜的阴道镜检查应是:(1)整个移行带及鳞柱交界区均能见到;(2)病变的全范围均能看到;(3)组织学、细胞学及阴道镜检查结果一致;(4)颈管诊刮。若颈管诊刮见到有间变组织(dysplastic tissue)则为阳性。本文报道712例异常宫颈涂片者进行阴道镜检查,所有都做了宫颈管诊刮。126例为颈管诊刮阳性。其中66例可得手术标本做病理检查。根据颈管诊刮间变组织量多少分为(?)组:第1组间变组织<10%;第2组10～50%;第3组>50%,比较颈管间变组织量与手术标本间变符合率:第1组为80%;第2组56%;第3组60%。宫颈管阳性者最后组织学诊断为3级者占62.1%;     

卵巢癌腹水的腹腔内化疗——附12例疗效分析

卵巢癌患者约有1/3同时伴有腹水。晚期卵巢癌的腹水是很难控制的。大量腹水可导致腹胀、肠胃功能紊乱、呼吸困难及心动过速等,给患者带来极大的痛苦。迄今尚未见有控制卵巢癌腹水的特效方法。过去许多学者曾有些尝试,试图控制或消除腹     

实行“首位奖励 末位淘汰”制度的实践与思考

随着市场经济的不断完善和发展,卫生事业 的改革已逐步深入,医院要更好地适应社会主义 市场经济的发展,必须逐步建立起有责任、有激 励、有约束、有竞争的运行机制。根据这一总的思     

流行性出血热的胃镜下改变

笔者于2004年3月～11月间通过胃镜观察因上腹部不适等消化道症状就诊的9例患者，镜下均有特征性表现，最终临床诊断为流行性出血热。