清热凉血法治疗高雌激素血症合并子宫不规则出血临床研究

目的:研究探讨清热凉血法治疗高雌激素血症合并子宫不规则出血(AUB)的临床疗效。方法:选择80例高雌激素血症合并子宫不规则出血患者,按治疗方案分为对照组(口服地屈孕酮治疗)38例和观察组(口服地屈孕酮+清热凉血法治疗)42例,观察比较两组治疗前、治疗后及停药3个月后的血清雌二醇(E2)、血红蛋白含量(Hb)及子宫内膜厚度;比较两组治疗前后的中医症候积分、平均经期天数、平均月经周期、凝血相关指标变化;并比较两组治疗后平均止血天数、总有效率和停药3个月的复发率。结果:观察组治疗后与停药3个月后的血清E2、Hb水平及子宫内膜厚度比较差异无统计学意义(P>0.05);观察组治疗后与停药3个月后的血清E2、子宫内膜厚度均比治疗前明显下降(P<0.05),Hb水平比治疗前明显升高(P<0.05),改善程度均优于对照组同期水平(P<0.05)。观察组治疗后的中医症候积分、各项凝血指标均比治疗前明显下降(P<0.05),平均经期天数、平均月经周期均比治疗前明显缩短(P<0.05),改善程度均优于对照组同期水平(P<0.05)。观察组治疗后平均止血天数明显低于对...     

心血管内科护理的安全问题及对策

随着时代的发展与社会的进步,心血管疾病是一种常见疾病,搞好心血管内科护理活动,才能为更多的心血管疾病患者提供可靠的生命保障,才能为病人及其家属提供一个值得信赖的环境和口碑,才能为医学上心血管病治疗方面的进步提供稳定的平台。     

壮医灯心草灸治疗甲亢疗效机理研究

目的:观察壮医灯心草疗法治疗甲状腺机能亢进症(甲亢)的临床疗效.方法:将200例甲状腺机能亢进症门诊患者随机分为观察组和对照组,每组100例,观察组采用壮医灯心草灸疗法治疗,对照组采用口服他巴唑治疗.观察两组的临床疗效,15次为1疗程,共4个疗程观察总疗效,甲状腺激素水平变化.结果:两组总有效率(91.0％与79.0％)比较有显著性差异(P＜0.05).结论:壮医灯心草灸治疗甲状腺机能亢进症具有较好的临床疗效,其作用机理是通过灯心火对皮肤的温热刺激,借助经络的传导作用,起到“外惹内效”之功,以疏通经脉,调和气血,调整脏腑的阴阳平衡,促进机体功能活动恢复正常,从而抑制甲状腺激素分泌、阻断甲状腺激素吸收,达到治疗甲亢的目的.     

南平市2012年饮水型地方性氟中毒调查监测分析

目的 掌握南平市饮水型地方性氟中毒病情变化及实施改水工程后的防治效果,为制定防制措施提供依据.方法 按《福建省饮水型地方性氟中毒监测方案》开展水厂水氟、末梢水氟、儿童氟斑牙、成人尿氟及改水工程质量调查等项目监测.结果 建阳市3个病区水厂水和末梢水氟含量＜0.1 mg/L,延平区、政和县＜0.2 mg/L;8～12岁儿童检出氟斑牙可疑患者1例;25岁以上且在当地居住5年以上人群的尿氟浓度几何均值为0.32 mg/L;6个改水工程均属简易小型集中供水,改水率达100.0％,覆盖2 013人,受益率100.0％.结论 南平市6个病区村各项指标均达到基本控制饮水型地方性氟中毒的标准,以改水降氟和病情监测为主要防制手段,是防制饮水型地方性氟中毒的根本策略.     

上海市浦东新区妇女绝经年龄及行经年限调查与影响因素分析

Objective To investigate natural spontaneous menopausal age , menstruation span and their relationship with menarche age and parity in Pudong district of Shanghai. Methods From Jan 2007 to Jul 2008, 15 083 spontaneous menopause women undergoing cervical cancer screening were enrolled in this study. The questionnaire included menarche age, parity, spontaneous menopausal age and menstruation span. Those women were divided into four groups based on age, which were group of 56 -60, 61 -65, 66 -70 and more than 70. Analysis of variance (ANOVA) was used for comparing difference between menopausal age and menstruation span. Multiple factor regressions was used to analyze the relationship between menarche age, parity and menopausal age and menstruation span. Results (1) Spontaneous menopausal age: the minimum was 29 years old, the maximum was 61 years old, and the mean age was (50.6 ±3.7)years old. The mean spontaneous menopause age were (50.9 ± 3.4), ( 50.7 ± 3.7 ), (50.0 ± 4.1 ), (49.6 ±4.0) years in groups of 56 -60, 61 -65, 66 -70 and more than 70 years. With the increasing age range in four groups, the increasing trends of menopausal age were observed, which the difference of 1.36 year was shown between groups of 56 - 60 and more than 70 years. (2) Menstruation span: the mean of menstruation span was (34.3 ± 4.1 ) years, which the minimal age of 12 years and maximal age of 48 years were recorded. (34.6 ± 3.8), (34.3 ± 4.1 ), (33.9 ± 4.6), (33.2 ± 4. 5) were observed in groups of 56 - 60,61 -65, 66 -70 and more than 70 years. With the increasing age range in four groups, the increasing trends of menstruation span were observed, which the difference of 1.41 year was shown between groups of 56 –60 and more than 70 years. (3)The impact of menarche age on menopausal age and menstruation span: there was no correlation between menarche age and menopausal age ( r = 0.02); however, menstruation span was found to be negatively correlated with the menarche age ( r = - 0.43 ). (4) The impact of parity on menopausal age and menstruation span: the mean menopausal age of women who had 1 -2 deliveries was significantly higher than those had no delivery or more than 3 deliveries ( P < 0.05 ). However, there was no difference in menopausal age between women with 1 and 2 deliveries or between women without delivery and more than 3 deliveries (P > 0.05). Menstruation span of women with 1 delivery was significantly longer that those with more than 1 delivery( P < 0.05 ), similarly, women with 2 deliveries had longer menstruation span than women without delivery or more than 3 deliveries(P < 0.05 ). There were no difference in menstruation span between women with more than 3 deliveries and without delivery ( P >0.05 ). (5) Multifactor regression analysis for menstruation span: menarche age was correlated with menstruation span negatively ( r = - 0.97,P <0.001 ). There was significantly different menstruation span between group of 61 -65, 66 -70 or more than 70 years and group of 56-60 (r= -0. 18, P=0.020; r= -0.78,P <0.001 and r= - 1.23,P<0.001). Menstruation span in women with 1 -2 deliveries was significantly longer than that of women without delivery or more than 3 deliveries. (6)Multifactor logistic analysis of menopausal age: there was no association between menarche age and menopausal age, however, significant differences were found in mean menopausal age between different groups, which show that menopausal age of group 56 - 60 years was significant higher than the other groups, including age-group 61 -65 years ,66 -70 years and over 70 years ( r = - 0.18, P = 0.020; r = - 0.78,P < 0.001; r = - 1.23, P < 0.001 ). Menopausal age in women with 1 - 2 deliveries was significantly higher than those of women without delivery or with more than 3 deliveries,however, no difference between women with 1 and 2 deliveries or between women without deliveries and more than 3 deliveries was observed. Conclusion (1) Menopausal age and menstruation span exhibited increasing trends in Pudong district of Shanghai. (2) Menarche age and parity were the important factors influencing menopausal age and menstruation span. (3) With younger age of menarche, the menstruation span become longer. (4) Deliveries of 1 -2 times can significantly delay the menopause and prolong menstruation span, however, the multiple deliveries ( ≥ 3 times) had no significant impact on menopausal age and menstruation span.     

原发性高血压患者血浆脑钠肽的测定

目的探讨高血压患者脑钠钛（BNP）变化水平和左室肥厚（LVH）的临床指标的相关性。方法选取原发性高血压患者无左室肥厚患者32例（NLVH组）,高血压合并左室肥厚患者31例（LVH组）及血压正常的健康体检者（对照组）31例,采用酶联免疫吸附法（ELISA）测定其BNP浓度,采用超声心动图检测左室重量指数（LVMI）,观察BNP水平和左室重量指数的关系。结果LVH组BNP水平显著高于NLVH纽及对照纽,差异有统计学意义（P〈0．01）。NLVH组高于对照组（P〈0．01）,BNP和左室重量指数呈正相关性（P〈0．01）。结论BNP水平变化可以作为高血压及左室肥厚的监测的重要指标。     

金果榄的研究进展

金果榄系防己科植物金果榄Tinospora capillopies Gagenep的干燥块根。异名：青牛胆、地苦胆、雪里开等。同属植物心叶青牛胆Tinospora cardifolia,有降血糖作用。主产于广西、湖南等地,有清热解毒、利咽、止前功效,味苦寒,入肺、胃经,民间临床用于治疗急性咽喉炎、扁桃体炎等,^[1]对金果榄的名称鉴别考证、^[2]植物形态和性状鉴定已有报道,^[3、4]金果榄具有多方面生理活性和药理作用,近年来,国内外学者提出许多篇研究报告。现就金果榄的化学成分、药理作用、临床应用作一简要综述。     

化瘀润肺法治疗老年人肺炎

笔者针对老年人生理病理特点,以活血化瘀、润肺清热法为主,治疗老年人肺炎18例,同时与西药治疗组10例对照,疗效满意,现报告如下.     

北京市药品监督管理系统率先实现垂直管理——北京市药品监督管理局区县分局成立

2001年9月10日是一个值得纪念的日子,在这一天,北京市政府隆重召开大会,宣布在全市18个区县正式成立北京市药品监督管理局区县分局.各区县分局的成立标志着北京市的药品监督管理系统已在全国率先实现垂直管理.在当前机构改革,不断精简机构的同时,却在各区县纷纷成立药监分局,可见国家对人民用药安全有效的足够重视,也可见国家在打击假、劣药上的决心与力度.