新疆不同地区维吾尔族苯硫脲尝味遗传多态性研究

采用改进阈值法,测试统计分析了新疆维吾尔自治区内不同地区的7 469例(男性3 831例、女性3 638例)维吾尔族中学生和大学生(12~25岁)苯硫脲尝味能力的阈值分布、味盲率、基因型频率和基因频率.结果显示维吾尔族苯硫脲尝味能力的阈值分布和味盲率具有本民族的自身特点.在新疆维吾尔自治区内,不同地区的维吾尔族苯硫脲尝味味盲率不同,并具有极显著性差异(P0.01),从东部(哈密地区)到西部(喀什地区),苯硫脲味盲率逐渐增加,平均味盲率为24.13%,介于欧罗巴人种和其他有色人种之间,该现象与人类学关于现代维吾尔族的族源、人种构成及演化过程的"合流说"相吻合.     

海狸鼠染色体核型及带型的研究

对海狸鼠（ＭｙｏｃａｓｔｏｒＣｏｙｐｕｓ）染色体的普通核型和显带核型（Ｇ带，Ｃ带，Ａｇ－ＮＯＲ）进行了分析，并着重分析了Ｃ－带核型，Ａｇ－ＮＯＲ核型中所存在的多态性，提示今后应探索其多态性与经济性状的相关。     

聚醚酮酮的合成、结构与性能

合成了聚醚酮酮，并用广角Ｘ射线、红外及差示扫描丘热技术研究聚醚酮酮及其共聚体系。研究表明这种体系存在多晶型结构，第Ⅰ晶型与通常聚醚醚酮晶型相同；第Ⅱ晶型与第Ⅰ晶型不同。第Ⅱ晶型晶胞参数ａ＝０．３９９７ｎｍ，ｂ＝０．５６６７ｎｍ，ｃ＝０．９８６１ｎｍ。改变共聚体系分子链结构及制样与热处理条件均可得到这两种晶型的变化情况。     

Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2

Many neuropsychiatric disorders are considered to be related to the dysregulation of brain serotonergic neurotransmission. Tryptophan hydroxylase-2 (TPH2) is the neuronal-specific enzyme that controls brain serotonin synthesis. There is growing genetic evidence for the possible involvement of TPH2 in serotonin-related neuropsychiatric disorders; however, the degree of genetic variation in TPH2 and, in particular, its possible functional consequences remain unknown. In this short review, we will summarize some recent findings with respect to the functional analysis of TPH2. Received 12 September 2005; received after revision 25 October 2005; accepted 31 October 2005     

基于容器的面向对象技术的多态性实现及应用

多态性是面向对象技术的重要特性之一,C++语言支持静态多态性和动态多态性.静态多态性主要通过函数重载和运算符重载来实现,动态多态性主要通过虚函数和动态联编来实现.多态性使程序设计更加灵活、易维护和易扩展.介绍了动态多态性在C++语言中的实现机制,提出基于容器的动态多态性实现技术,结合VC++6.0中绘图软件开发实例,描述基于容器的绘图过程及动态多态性应用.     

新疆4个品种绵羊群体遗传结构的研究

采用垂直聚丙烯酰胺凝胶电泳法，对巴什拜羊(43只)、哈萨克羊(41只)、中国美利奴羊(新疆军垦型)(42只)、罗姆尼羊(45只)的3个血清蛋白位点进行了多态性分析，计算了血清转铁蛋白(Tr)、酯酶(Es)及白蛋白(Alb)的基因型和基因频率及各位点的杂合度、群体平均杂合度及群体信息度。结果表明：4个品种绵羊在3个位点均为多态，在多态座位中，Tr、Alb和Es分别出现了4、3和3种表型，分别受4、2和2个共显性等位基因控制。X^2检验显示，4个品种绵羊在3个座位上均处于哈代-温伯格平衡状态(P≥0．05)，并且均表现出较高的杂合度，其值分别是：巴什拜羊0．588l、中国美利奴羊(新疆军垦型)0．5352、哈萨克羊0．5290、罗姆尼羊0．4964。     

CD14基因多态性与强直性脊柱炎的关联性研究

目的探讨CD14基因rs2569190位点的单核苷酸多态性与强直性脊柱炎易感性的关系.方法采用PCRRFLP方法对240例AS患者进行CD14基因多态性检测,并与140名健康对照者进行对比.结果 rs2569190位点基因型频率两组间差异具有统计学意义(χ~2=6.778,υ=2,P0.05);强直性脊柱炎组携带突变体A基因的频率高于对照组,差异具有统计学意义(χ~2=3.876,υ=1,P0.05).结论 CD14基因rs2569190位点单核苷酸多态性与强直性脊柱炎易感性存在关联,携带CD14突变体A基因者患AS风险较大.     

分子标记技术在作物育种中的应用与展望

回顾分子标记的发展,介绍了一些有代表性的分子标记在生态学,聚类分析,品种差异性分析以及分子育种中等多方面的应用,并总结了它们的优缺点.随着深度测序技术的发展和多种序列信息库的完善,预测了未来分子标记的发展方向——功能性分子标记(Functional molecular marker),这种新型的分子标记技术利用了基因中的一些功能元件或者重要的单碱基多态性(SNP)位点,提高了在应用中的分辨率和灵敏度.     

Identification of three major Bemisia tabaci biotypes in China based on morphological and DNA polymorphisms

The sweet potato whitefly, Bemisia tabaci, is a complex species, and many of its biotypes are important agricultural pests. The B and Q biotypes are invasive and coexist with the native Cv biotype on vegetable and ornamental crops in China. In this study, these three biotypes were identified based on their morphological characteristics, RAPD–PCR analysis, and DNA sequences of the COI gene. The anterior and posterior wax fringes of the B, Q, and Cv biotypes significantly differed from each other. Based on this morphological characteristic, the three biotypes can easily be distinguished in greenhouses and fields. Genomic DNA RAPD–PCR band patterns also revealed differences between these biotypes using the H16 primer. The B biotype has three bright DNA bands between 250 and 600 bp, the Q biotype only has one bright band at 300 bp, while the Cv biotype has no band between 250 and 500 bp. Both the Cv and Q biotypes have two bright bands at 750 and 1000 bp while the B biotype has only one band at 1000 bp. Based on the COI gene, the genetic identity between B and Cv, B and Q, and Q and CV was 85.8%, 94.7%, and 86.0%, respectively. The MP tree indicated that the phylogenetic relationship between the B and Q biotypes is much closer than that between the B and Cv or the Q and Cv biotypes. The uses of the morphological, RAPD–PCR, and DNA sequencing methods in biotype identification of B. tabaci are discussed.