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61.
62.
张景岳补肾阴阳观之探析 总被引:2,自引:0,他引:2
Ji L 《Zhonghua yi shi za zhi (Beijing, China : 1980)》2001,31(4):234-236
明代医学张景岳善用温补,重视补肾,并从理论的深度与实践的要求,认为:补肾之法,真阴为本,育阴之用,涵阳为度;扶阳之炒,培阴生阳,形成了独特的补肾阴阳观的学术思想。 相似文献
63.
本文通过对《妇人规》的研究,总结张景岳辨证论治妇科疾病的学术思想特色,如经病形成有多因,调经之要须辨证;妊娠胎气不安,证本非一,治亦不同,辨证祛病;安胎要法,祛其所病,便是安胎,因病而药之,不可拘泥;产后有虚证、不虚证、全实证及虚实夹杂证之别,产后应明辨虚实,因证而治病。 相似文献
64.
Wang S 《Zhonghua yi shi za zhi (Beijing, China : 1980)》1999,29(2):74-76
军事生涯是张景岳温补思想的基础,并对其果断气质的形成以及将军事理论与医学理论的结合方面产生了一定影响,在中国军事医学史上有重要意义 相似文献
65.
张磊老师是国家第二批师承制导师,在当今国家大力发展中医的情况下,如何遵循中医药科学自身的发展规律,继承弘扬传统中医特色和优势,培养和造就一批名中医,是新形势下的一个重要命题。本文根据作者侍医过程中的心得体会,从写实的角度,思考张磊成为名医的必然性;文章从他艰苦勤奋的学习历程、充满强烈事业心和责任感的工作经历出发,结合其知识结构,治学态度,高尚情操,敬业精神,专业素养,以及个人人格魅力,展示张磊多才多艺的丰富医学人生,从而为大家学习中医树立榜样。 相似文献
66.
郑念理 《辽宁中医药大学学报》2000,(1)
学习张仲景《伤寒论》 ,《金匮要略》对水肿病的论述及治疗。主要从发汗、利小便、逐水、化瘀利水、培中、温肾等 6个方面进行分析归纳 ,并列举有关方剂进行论述 ,以供对水肿病治疗的临床借鉴。 相似文献
67.
董振德 《中国中医药现代远程教育》2021,(4)
文章介绍张天文教授治疗呃逆的临床经验,张教授认为呃逆的病位在膈;病变的关键脏腑在胃,并与脾、肝、肺、肾密切相关;主要病机为膈间气机逆乱,胃气上逆动膈;人体以五脏为中心,五脏之间生理上相互协调,病理上相互影响,因此,治疗呃逆应当从整体观念与五脏辨证入手,“谨守病机,各司其属”,不应单纯见呃止呃,并且针药并举,各发其长。 相似文献
68.
H. Wang X. Du W.-H. Chen J. Lou H.-L. Xiao Y.-M. Pan H. Chen N. An Q.-X. Zhang 《Transplantation proceedings》2018,50(1):104-109
Background
The chimeric antigen receptor (CAR) consists of an antigen recognition moiety from a monoclonal antibody fused to an intracellular signalling domain capable of activating T cells. The specific structure of the CAR molecule has been used in various basic research and clinical settings to detect CAR expression, but it is necessary to develop more specific and simpler monitoring methods to observe real-time changes.Materials and Methods
To develop a quantitative assay for the universal detection of DNA from anti-CD19 CAR-T cells, a TaqMan real-time quantitative polymerase chain reaction (qPCR) assay was developed using primers based on FMC63-28Z gene sequences. We identified the numbers of copies of CAR gene on T cells transduced with the CAR gene that were obtained from peripheral blood.Results
The assay had a minimum detection limit of 10 copies/μL and a strong linear standard curve (y = ?3.3682x + 38.594; R2 = 0.999) within the range of the input CAR gene (10–107 copies/μL). The reproducibility test showed a coefficient of variation ranging from 0.63%–1.65%. Real-time qPCR is a highly sensitive, specific, reproducible, and universal method that can be used to detect anti-CD19 CAR-T cells in peripheral blood. 相似文献69.
Honglin Dong Tian Du Shyamal Premaratne Cynthia X. Zhao Qinqin Tian Yongjun Li Sheng Yan Wayne W. Zhang 《Journal of vascular surgery》2018,67(4):1120-1126
Background
Rupture of atherosclerotic plaques and the resulting thrombosis are vital causes of clinical ischemic events. Recent studies have shown that ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin motifs 4) is a pathogenic factor of plaque vulnerability in mice. However, the relationship between ADAMTS4 and carotid atherosclerotic vulnerable plaques in humans remains unclear.Methods
Forty-eight carotid atherosclerotic plaque specimens were obtained from 48 carotid artery stenosis inpatients undergoing carotid endarterectomy. We performed hematoxylin and eosin and Movat pentachrome staining for histologic characteristics; immunohistochemical staining for ADAMTS4, versican, and macrophages; and serologic tests for ADAMTS4. Patients were divided into stable and vulnerable groups on the basis of histologic characterization according to the classification criteria of the American Heart Association. Comparison between the groups was carried out using SPSS 17.0 (SPSS Inc, Chicago, Ill).Results
Expression of ADAMTS4 in the plaque and its serum concentration were significantly higher in the vulnerable group compared with the stable one (P = .004 and P = .021, respectively), whereas the expression of versican was lower in the vulnerable group than in the stable group (P = .015). Univariate analysis revealed that the incidence of symptomatic cerebral ischemic events and ADAMTS4 serum levels were statistically higher in the vulnerable group compared with the stable group (P = .021 and P = .029, respectively). Multivariate analysis showed that ADAMTS4 was an independent risk factor (odds ratio, 1.14; P = .038).Conclusions
Our study revealed that ADAMTS4 expression was upregulated during carotid atherosclerotic plaque development. Serum levels of ADAMTS4 were associated with increased plaque vulnerability in both symptomatic and asymptomatic patients with carotid artery stenosis. ADAMTS4 may be a potential biomarker for plaque vulnerability. 相似文献70.