植物抗性基因识别中的随机森林分类方法

为了解决传统基于同源序列比对的抗性基因识别方法中假阳性高、无法发现新的抗性基因的问题,提出了一种利用随机森林分类器和K-Means聚类降采样方法的抗性基因识别算法。针对目前研究工作中挖掘盲目性大的问题,进行两点改进:引入了随机森林分类器和188维组合特征来进行抗性基因识别,这种基于样本统计学习的方法能够有效地捕捉抗性基因内在特性;对于训练过程中存在的严重类别不平衡现象,使用基于聚类的降采样方法得到了更具代表性的训练集,进一步降低了识别误差。实验结果表明,该算法可以有效地进行抗性基因的识别工作,能够对现有实验验证数据进行准确的分类,并在反例集上也获得了较高的精度。     

一种基于数据竞争的高分辨率图像的聚类分割算法

近些年,机器人技术得到了迅猛的发展,应用越来越广泛.随着机器人技术的推广和普及,对机器人使用的要求也越来越高,其中对智能机器人的要求尤显迫切.机器视觉是智能机器人研究领域的一个重要研究方向.在机器人视觉系统中,核心问题是目标提取,对目标实时、准确、快速提取的关键技术是图像分割.由于机器人感知的环境的复杂性及目标的多样性,往往导致机器人感知获得的图像数据量较大且图像本身存在不可预知的复杂性,这就对准确的目标分割和提取处理提出了挑战性问题.本文针对高分辨率图像数据集的分割处理,提出一种新的聚类算法,即根据数据点能量和的大小识别类代表点和类成员点,通过数据点间的竞争识别出最有能力成为簇成员的数据点,并将其与mean shift聚类算法有效地结合应用于彩色图像分割问题中,能够快速高效地实现高分辨率图像的目标分割,并得到较好的图像分割效果.实验结果表明,本文算法在分割效果和分割效率上明显优于传统聚类算法.     

Fuzzy-ART背景抑制的单帧红外弱小目标检测

针对现有背景抑制算法未能有效地抑制背景而导致目标检测率低的问题,提出一种基于模糊自适应共振理论(Fuzzy-ART)进行背景抑制、基于行列k均值(k-means)聚类实现阈值分割的单帧红外弱小目标检测算法.首先依据红外成像原理仿真生成红外弱小目标训练样本;然后采用Fuzzy-ART神经网络建立目标模型,并以此分析各像素点的目标模糊隶属度来抑制背景杂波;最后采用基于行列k-means聚类的自适应阈值分割算法来检测真实目标.实验结果表明,该算法能有效地抑制背景杂波和突显目标,并能有效地提高信噪比检测弱小目标.     

改进的蠕虫特征自动提取模型及算法设计

文章提出了一种基于序列比对的蠕虫特征自动提取模型,该模型针对现有蠕虫特征自动提取系统的可疑蠕虫样本流量单来源和粗预处理等问题,提出了对网络边界可疑流量和蜜罐捕获网络流量统一的聚类预处理,并使用改进的T-Coffee多序列比对算法进行蠕虫特征提取。实验分别对Apache-Knacker和TSIG这两种蠕虫病毒进行特征提取,从实验结果可以看出文章提出的模型产生的特征质量优于比较流行的Polygraph、Hamsa两种技术。     

浅析医院计算机系统的数据备份

为了满足医院信息系统发展的备份容灾体系发展,通过对医院计算机系统的数据备份相关重点问题进行详细分析,并对医院信息系统现状作了较详尽的备份与容灾规划。     

Group technology based adaptive cell formation using predator-prey genetic algorithm

In recent years, there has been a considerable growth of application of group technology in cellular manufacturing. This has led to investigation of the primary cell formation problem (CFP), both in classical and soft-computing domain. Compared to more well-known and analytical techniques like mathematical programming which have been used rigorously to solve CFPs, heuristic approaches have yet gained the same level of acceptance. In the last decade we have seen some fruitful attempts to use evolutionary techniques like genetic algorithm (GA) and Ant Colony Optimization to find solutions of the CFP. The primary aim of this study is to investigate the applicability of a fine grain variant of the predator-prey GA (PPGA) in CFPs. The algorithm has been adapted to emphasize local selection strategy and to maintain a reasonable balance between prey and predator population, while avoiding premature convergence. The results show that the algorithm is competitive in identifying machine-part clusters from the initial CFP matrix with significantly less number of iterations. The algorithm scaled efficiently for large size problems with competitive performance. Optimal cluster identification is then followed by removal of the bottleneck elements to give a final solution with minimum inter-cluster transition cost. The results give considerable impetus to study similar NP-complete combinatorial problems using fine-grain GAs in future.     

服务器集群负载均衡的建模与仿真研究

研究服务器集群负载优化调试问题,各服务器负载能力差异较大,要求尽可能使每一个服务器的负载均衡,传统方法没有考虑负载动态变化特点,导致服务器集群负载极不均衡,系统性能差。为提高集群系统的整体性能,提出一种基于遗传算法的服务器集群负载均衡算法。首先根据负载均衡目标建立数学模型,然后采用遗传算法模型进行求解。仿真结果表明,遗传算法提高了服务器集群系统吞吐量,使系统负载更加均衡,使整个集群系统的资源得到充分利用。     

用正电子湮没寿命技术研究塑性变形纯Ni的回复过程

本文用正电子湮没寿命方法研究了塑性变形镍(含0.01％杂质)的回复过程的特点及杂质在缺陷回复过程的作用和影响,计算了形变为10％的试样中的位错密度及形成空位团的有效空位浓度。     

Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly

Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. Most information concerning LIAS and its mechanism has been determined from prokaryotic enzymes. Herein, we detail the expression, isolation, and characterization of human LIAS, its reactivity, and evaluation of natural iron–sulfur (Fe–S) cluster reconstitution mechanisms. Cluster donation by a number of possible cluster donor proteins and heterodimeric complexes has been evaluated. [2Fe–2S]-cluster-bound forms of human ISCU and ISCA2 were found capable of reconstituting human LIAS, such that complete product turnover was enabled for LIAS, as monitored via a liquid chromatography–mass spectrometry (LC–MS) assay. Electron paramagnetic resonance (EPR) studies of native LIAS and substituted derivatives that lacked the ability to bind one or the other of LIAS’s two [4Fe–4S] clusters revealed a likely order of cluster addition, with the auxiliary cluster preceding the reducing [4Fe–4S] center. These results detail the trafficking of Fe–S clusters in human cells and highlight differences with respect to bacterial LIAS analogs. Likely in vivo Fe–S cluster donors to LIAS are identified, with possible connections to human disease states, and a mechanistic ordering of [4Fe–4S] cluster reconstitution is evident.     

基于数据融合的ABC-SVM社区疾病预测方法

针对现有社区医疗服务中的疾病预测方法存在数据利用率低、疾病分析类型单一、自动化程度差、疾病预测效果不理想等不足,提出在物联网大数据环境下可用于社区医疗的健康数据融合及疾病预测方法. 通过主成分分析(PCA)和聚类分析对社区中居民的生理指标数据进行特征提取;结合人工蜂群(ABC)算法构造支持向量机(SVM)非线性分类器对数据进行特征级融合分析并预测潜在疾病. 实验结果表明,所提方法的疾病识别准确率达到93.10%,相较于传统SVM方法和BP神经网络方法分别提高17.24% 和72.41%. 该方法能够在提高数据利用率、降低计算资源消耗的前提下有效识别多种潜在疾病,可实现疾病早发现、早预防、早治疗;可广泛应用于社区健康管理、老年社区监护甚至临床医疗.