β-淀粉样多肽自聚集抑制剂的电化学筛选方法研究

β-淀粉样多肽（Amyloidbeta,Aβ）的聚集物具有神经细胞毒性,可导致神经元凋亡,从而诱导阿尔茨海默症（Alzheimer’s disease,AD）的发生。能够抑制AB自聚集行为的化合物称为AB自聚集抑制剂。该抑制剂可抑制Aβ有毒聚集物的产生,从而降低Aβ所引起的神经细胞毒性,对AD病有一定的治疗效果。因此。筛选AB自聚集抑制剂对于AD的治疗有着重要的意义。在数以千万计的化合物中,要筛选出对Aβ自聚集有抑制效果的化合物需要借助众多的仪器和研究方法。该文总结了筛选AB自聚集抑制剂的几种方法．重点综述了几种低成本、快速、灵敏的电化学筛选方法。Aβ自聚集抑制剂的筛选对临床上AD病的治疗提供了理论基础,为治疗AD病这一复杂科学问题的研究起到了促进作用。     

智能电网中家域网安全数据汇聚与调度方法研究

智能电网中通信网络的安全是实施智能电网的一个重要环节。用户信息的隐私保护是智能电网安全服务的一个主要任务。智能电网中用户信息隐私保护主要围绕智能电表数据的机密性和匿名性展开。本文以家域网作为智能电网通信网络的一个基本数据汇聚与调度单元,提出了一种安全的网内数据汇聚与调度方法,从而保证了智能家居设备的用电信息的机密性和匿名性。采用NS-2对本文提出的网内方法进行了仿真研究。仿真结果表明,本文提出的网内数据汇聚与调度方法与传统方法相比具有较高的实用性。     

SRA-MSDU: Enhanced A-MSDU frame aggregation with selective retransmission in 802.11n wireless networks

The main goal of the IEEE 802.11n standard is to achieve more than 100 Mbps of throughput at the MAC service access point. This high throughput has been achieved via many enhancements in both the physical and MAC layers. One of the MAC enhancements is the frame aggregation in which multiple frames are concatenated into a single large frame before being transmitted. The 802.11n MAC layer defines two types of aggregation, aggregate MAC service data unit (A-MSDU) and aggregate MAC protocol data unit (A-MPDU). The A-MPDU outperforms A-MSDU due to its large aggregation size and the subframes retransmission in erroneous channels. However, in error free channels and under the same aggregation size the A-MSDU performs better than the A-MPDU due to its smaller headers. Thus, adding a selective retransmission capability to the A-MSDU would improve the system performance. In this paper, we have proposed an MSDU frame aggregation scheme that enables selective retransmission at the MSDU level without altering the original MAC header. In this proposed scheme an implicit sequence control mechanism has been introduced in order to keep the frames in sequence and preserve their correct order at the receiver side. The results show that the proposed scheme improves the system performance in terms of throughput and delay even under highly erroneous channels.     

一种基于数值积分的过程神经元网络训练算法

针对过程神经元网络的训练问题,提出了一种基于数值积分的学习算法。直接采用数值积分进行网络中动态样本与连接权函数的时域加权聚合运算,采用梯度下降法实现连接权函数特征参数及网络性质参数的调整。设计了基于梯形积分、辛普森积分、柯特斯积分等3种过程神经元网络数值积分训练方法,以太阳黑子数据预测为例进行仿真实验,结果表明,基于数值积分的过程神经元网络训练算法是有效的,其中辛普森积分算法的性能最优。     

基于蚁群算法的无线传感网络中心点融合算法研究

建立级别梯度场是无线传感器网络中心点融合算法的重要组成部分。采用泛洪方法向外扩散梯度,会造成严重的能量消耗问题。为了节省传感器网络中的能量,将蚁群算法用于建立级别梯度场阶段,提出了基于蚁群算法的无线传感网络中心点融合算法。仿真实验验证了该方法的可行性。研究结果表明,基于蚁群算法的中心点融合算法可以显著地减少无线传感器网络的能量消耗,延长无线传感器网络的生命周期。     

基于主元分析的无线传感器网络数据融合研究

由于传感器节点能量有限且难以补充,无线传感器网络设计的一个重要目标就是在严格的能量约束下最大化网络的生存时间。网内数据融合是减少传感器节点数据传输量、降低网络总能耗,最大化网络生命周期的一种有效途径。本文利用主元分析法PCA中的数据降维技术,提出一种在无线传感器网络的簇内进行数据融合的方法。该方法的主要思想是利用网络的簇头节点对具有一定相关性的多个簇内节点的实测变量进行线性变换,将其转化为少数几个不相关的综合指标后再进行数据转发,从而达到减少网络中的数据传输量和能量消耗的目的。理论分析和实例验证表明了该方法的有效性和实用性。     

A relational–XML data warehouse for data aggregation with SQL and XQuery

Integrating information from multiple data sources is becoming increasingly important for enterprises that partner with other companies for e‐commerce. However, companies have their internal business applications deployed on diverse platforms and no standard solution for integrating information from these sources exists. To support business intelligence query activities, it is useful to build a data warehouse on top of middleware that aggregates the data obtained from various heterogeneous database systems. Online analytical processing (OLAP) can then be used to provide fast access to materialized views from the data warehouse. Since extensible markup language (XML) documents are a common data representation standard on the Internet and relational tables are commonly used for production data, OLAP must handle both relational and XML data. SQL and XQuery can be used to process the materialized relational and XML data cubes created from the aggregated data. This paper shows how to handle the two kinds of data cubes from a relational–XML data warehouse using extract, transformation and loading. Copyright © 2008 John Wiley & Sons, Ltd.     

An adaptive in-network aggregation operator for query processing in wireless sensor networks

A wireless sensor network (WSN) is composed of tens or hundreds of spatially distributed autonomous nodes, called sensors. Sensors are devices used to collect data from the environment related to the detection or measurement of physical phenomena. In fact, a WSN consists of groups of sensors where each group is responsible for providing information about one or more physical phenomena (e.g., group for collecting temperature data). Sensors are limited in power, computational capacity, and memory. Therefore, a query engine and query operators for processing queries in WSNs should be able to handle resource limitations such as memory and battery life. Adaptability has been explored as an alternative approach when dealing with these conditions. Adaptive query operators (algorithms) can adjust their behavior in response to specific events that take place during data processing. In this paper, we propose an adaptive in-network aggregation operator for query processing in sensor nodes of a WSN, called ADAGA (ADaptive AGgregation Algorithm for sensor networks). The ADAGA adapts its behavior according to memory and energy usage by dynamically adjusting data-collection and data-sending time intervals. ADAGA can correctly aggregate data in WSNs with packet replication. Moreover, ADAGA is able to predict non-performed detection values by analyzing collected values. Thus, ADAGA is able to produce results as close as possible to real results (obtained when no resource constraint is faced). The results obtained through experiments prove the efficiency of ADAGA.     

一种基于衰减集结的鲁棒预测控制器

高效鲁棒预测控制 (ERPC) 是一种在线计算量较小, 且控制性能较好的鲁棒预测控制算法. 但采用单一椭圆不变集的设计方法存在保守性. 本文采用衰减集结策略, 通过离线设计在系统状态空间中投影彼此正交的两个椭圆不变集, 在线进行凸组合的方法设计 ERPC 控制器, 使系统初始可行域进一步扩大, 并在一定程度上改善了控制性能.     

虚拟计算环境中的覆盖网技术

互联网资源的成长、自治和多样等特性给资源的有效聚合带来了巨大挑战.通过覆盖网动态组织互联网资源并支持资源的高效搜索,是虚拟计算环境中资源按需聚合的重要途径之一.文中概述了虚拟计算环境中覆盖网技术的研究进展.针对互联网资源的成长性和自治性等特点,阐述了基于Kautz图的高效覆盖网拓扑构造方法,进而给出了适用于任意正则图的通用覆盖网拓扑构造方法;针对互联网资源的多样性等特点,提出了支持分组的覆盖网拓扑构造方法;在此基础上,阐述了基于覆盖网的高效区间搜索技术,并对覆盖网拓扑的优化方法及其它复杂搜索技术进行探讨.