基于Windows的液压实时测试浅析

本文通过分析WINDOWS实时处理的局限性，提出了解决问题的几种机制；同时以液压元件的实时测试中断程序的实现为例说明了机制的应用，研究表明，这种机制较传统方法实用、有效。     

基于独立分量分析的图书馆个性化及时服务*

针对读者个性化服务质量的问题,提出了基于独立分量分析的图书馆个性化及时服务系统;简要给出了系统总体和个性化服务关键子系统的体系结构;重点讨论了利用独立分量分析方法改善系统个性化服务质量的问题.实验结果显示,利用此方法进行图书分类和读者群体聚类的效果较理想;读者群体和图书类别之间可产生随读者个性或图书主题变化而变化的动态映射关系,这种映射关系可以改善个性化服务质量.     

本体模块化的研究与实现

将软件工程中模块化的思想引入本体知识库的构建过程中,将本体组织成多个本体模块的集成形式,这样不仅方便了本体的构建,更有利于本体知识库的共享、重用和维护.用模块化的方法构建了汽车驾驶培训领域本体,建立方法库,在本体模块间用查询方式实现模块间的通信.这样的开发经验可以推广到其他领域.     

Antibody Libraries as Tools to Discover Functional Antibodies and Receptor Pleiotropism

Most antibodies currently in use have been selected based on their binding affinity. However, nowadays, antibodies that can not only bind but can also alter the function of cell surface signaling components are increasingly sought after as therapeutic drugs. Therefore, the identification of such functional antibodies from a large antibody library is the subject of intensive research. New methods applied to combinatorial antibody libraries now allow the isolation of functional antibodies in the cellular environment. These selected agonist antibodies have provided new insights into important issues of signal transduction. Notably, when certain antibodies bind to a given receptor, the cell fate induced by them may be the same or different from that induced by natural agonists. In addition, combined with phenotypic screening, this platform allows us to discover unexpected experimental results and explore various phenomena in cell biology, such as those associated with stem cells and cancer cells.     

Chemical Modification of Phage-Displayed Helix-Loop-Helix Peptides to Construct Kinase-Focused Libraries

Conformationally constrained peptides hold promise as molecular tools in chemical biology and as a new modality in drug discovery. The construction and screening of a target-focused library could be a promising approach for the generation of de novo ligands or inhibitors against target proteins. Here, we have prepared a protein kinase-focused library by chemically modifying helix-loop-helix (HLH) peptides displayed on phage and subsequently tethered to adenosine. The library was screened against aurora kinase A (AurA). The selected HLH peptide Bip - 3 retained the α-helical structure and bound to AurA with a K_D value of 13.7 μM. Bip - 3 and the adenosine-tethered peptide Bip - 3 - Adc provided IC₅₀ values of 103 μM and 7.7 μM, respectively, suggesting that Bip - 3 - Adc bivalently inhibited AurA. In addition, the selectivity of Bip - 3 - Adc to several protein kinases was tested, and was highest against AurA. These results demonstrate that chemical modification can enable the construction of a kinase-focused library of phage-displayed HLH peptides.     

Photocatalytic performance of Fe-substituted ZnAl2O4 powders under sunlight irradiation on degradation of industrial dyes

Using the sol–gel auto combustion method with diethanolamine (DEA) as fuel, a sequence of iron-substituted zinc aluminates, ZnFe_xAl_2-xO₄ powders, including variable Fe³⁺ ion concentrations (0 ≤ x ≤ 2) were effectively prepared. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), the Brunauer–Emmett–Teller (BET) method, UV–visible diffuse reflectance spectroscopy (UV-DRS), and vibrating sample magnetometer (VSM) were employed to examine the structures, chemical bonds, morphologies, composition, surface area, and optical properties as well as the magnetic behavior of the obtained samples. A single-phase spinel structure was obtained for the calcined aluminate powders with different interplanar spacing and crystallite sizes, as revealed by the classification results. The bandgap energy (E_g) of adapted aluminates was in the range of 2.04-3.14 eV, identified as being much lower compared to the pure sample (5.60 eV). Thus, Fe³⁺-substituted ZnAl₂O₄ samples could be successfully photoexcited using both ultraviolet and visible light, as suggested by the results. Examination of how the four main pollutant types decay when irradiated by sunlight was carried out to assess the samples and establish photocatalytic activity. These contaminants included rhodamine B (RhB), methylene blue (MB), methyl orange (MO), and methyl red (MR). The performance of photocatalytic degradation reached 98% after 150 min for all optimal samples of organic dyes. Besides, each of the altered photocatalysts could be recycled and displayed high stability. The S-shaped curve of ferrimagnetism can result in those samples as found by the magnetic measurements, though pure ZnAl₂O₄ displays diamagnetic characteristics. The adapted samples show intense improvement in the remanent magnetization (M_r) when compared to pure ZnAl₂O₄, signifying that magnetic photocatalyst recovery by applying an external magnetic field is easy. Thus, these results offer a convincing sign that ZnAl₂O₄ powders replaced by Fe³⁺ could provide the ability to aid in the ecologically friendly collection of solar energy.     

铂系低碳烷烃脱氢催化剂研究进展

综述了近年来国内外铂系低碳烷烃脱氢催化剂的技术现状与研究进展。首先从热力学角度论述了低碳烷烃脱氢反应与相关副反应的反应机理,随后分别从活性位点性能与催化脱氢的关系,氧化铝、分子筛等载体的作用,以及锡、碱金属、碱土金属、过渡金属等助剂改性对催化剂的影响等3个方面分析了铂系低碳烷烃脱氢催化剂的优势与存在的问题,进而探究了铂系脱氢催化剂的失活原因。最后对铂系脱氢催化剂的研究前景做了展望,提出该系列催化剂的主要发展方向包括降低贵金属铂的负载量、提高催化剂的稳定性、减少积炭副反应等。     

DMFC阳极催化剂用GRQD-NiCo2O4复合物的制备与电催化活性分析

采用水热法制备GRQD-NiCo₂O₄复合物,利用XRD、SEM及TEM分析其微结构,并探讨其作为DMFC阳极催化剂使用时的电化学性能。微结构分析表明所得GRQD-NiCo₂O₄复合物皆为具NiCo₂O₄单一相的尖晶石结构,且GRQD质量浓度高于0.25 g/mL后表面形貌将转变GRQD与NiCo₂O₄相互结合的状态。电化学分析表明添加GRQD可有效增强NiCo₂O₄的导电性并提升其电化学稳定性,其中GRQD质量浓度为0.25 g/mL时所得样品经500次循环测试后电流密度约为77.5 A/g,与循环5次后相比其电流密度剩余量最大（约为69.7%）,该样品作为DMFC阳极催化剂使用时性价比最佳。     

基于ObjectARX机械标准件三维参数化图形库软件的建立--AutoCAD的二次开发

机械设计CAD已由二维迅速向三维发展,这是设计领域的一次巨大变革.三维造型变量实体设计和三维装配设计已显现出明显的优势.而在三维装配设计中用量大的标准件、常用件的三维参变量实体造型库的不完备、不符合我国标准的状况自然是一个急待解决的重要环节.因此,有必要开发能快速、准确查询并能自动绘制三维机械标准件的软件,以提高设计速度,节省人力资源.文章以计算机图形学为理论基础,采用VC 6.0和ObjectARX3.0语言在AutoCAD2000设计平台上开发了三维参数化标准件库.简要介绍了系统的结构和关键技术的实现过程.     

Methanol Steam Reforming Over NiAl and Ni (M) Al Layered Double Hydroxides (M = Au, Rh, Ir) Derived Catalysts

This paper deals with an experimental investigation concerning steam reforming of methanol at 280, 340 and 380 °C over NiAl and Ni (Au, Rh or Ir)Al layered double hydroxides (LDHs) derived catalysts. Incorporation of noble metal ions into the NiAl-LDH framework was evidenced by XRD, TGA and TEM techniques. High selectivity to H₂ and CO₂ with less than 5% (volume) CO and trace CH₄ was observed over the NiAl-LDH catalyst. Whereas CO and H₂ are major products at lower temperatures after addition of Au, Rh and Ir to the NiAl-LDH system. They are significantly reduced with the concomitant increase in CH₄ and CO₂ as the temperature increased.