全文获取类型
收费全文 | 150553篇 |
免费 | 32578篇 |
国内免费 | 2397篇 |
学科分类
医药卫生 | 185528篇 |
出版年
2024年 | 512篇 |
2023年 | 4785篇 |
2022年 | 1165篇 |
2021年 | 3098篇 |
2020年 | 6049篇 |
2019年 | 2172篇 |
2018年 | 7418篇 |
2017年 | 7356篇 |
2016年 | 8438篇 |
2015年 | 8434篇 |
2014年 | 15506篇 |
2013年 | 15661篇 |
2012年 | 5515篇 |
2011年 | 5538篇 |
2010年 | 10396篇 |
2009年 | 14246篇 |
2008年 | 5811篇 |
2007年 | 4038篇 |
2006年 | 6505篇 |
2005年 | 3807篇 |
2004年 | 3070篇 |
2003年 | 2013篇 |
2002年 | 2089篇 |
2001年 | 3835篇 |
2000年 | 3050篇 |
1999年 | 3256篇 |
1998年 | 3654篇 |
1997年 | 3464篇 |
1996年 | 3371篇 |
1995年 | 3210篇 |
1994年 | 1948篇 |
1993年 | 1574篇 |
1992年 | 1386篇 |
1991年 | 1447篇 |
1990年 | 1092篇 |
1989年 | 1210篇 |
1988年 | 1053篇 |
1987年 | 867篇 |
1986年 | 914篇 |
1985年 | 727篇 |
1984年 | 565篇 |
1983年 | 529篇 |
1982年 | 520篇 |
1981年 | 412篇 |
1980年 | 367篇 |
1979年 | 338篇 |
1978年 | 336篇 |
1977年 | 411篇 |
1975年 | 291篇 |
1972年 | 314篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
61.
62.
63.
Breast Elastography: How to Perform and Integrate Into a “Best-Practice” Patient Treatment Algorithm
Breast elastography has been available for more than 15 years but is not widely incorporated into clinical practice. Many publications report extremely high accuracy for various breast elastographic techniques. However, results in the literature are extremely variable. This variability is most likely due to variations in technique, a relatively steep learning curve, and variability in methods between vendors. This article describes our protocol for performing breast elastography using both strain elastography and shear wave elastography, which produces high sensitivity and specificity. Additionally, we will describe the most commonly known false-positive and false-negative lesions as well as how to detect them. 相似文献
64.
The term “oligometastatic prostate cancer” refers to a heterogeneous group of disease states currently defined solely on the basis of clinical features. Oligorecurrent disease, de novo oligometastases, and oligoprogressive disease likely have unique biologic underpinnings and natural histories. Evidence suggesting the existence of a subset of patients who harbor prostate cancer with limited metastatic potential currently includes disparate and overwhelmingly retrospective reports. Nevertheless, emerging prospective data have corroborated the “better-than-expected,” retrospectively observed outcomes, particularly in the setting of oligorecurrent prostate cancer. Improved functional imaging with prostate-specific membrane antigen-targeted strategies may enhance the identification of patients with oligometastatic prostate cancer in the short term. In the long term, refinement of the oligometastatic case definition likely will require biologic risk-stratification schemes. To determine optimal treatment strategies and identify patients most likely to benefit from metastasis-directed therapy, future efforts should focus on conducting high-quality, prospective trials with much-needed molecular correlative studies. 相似文献
65.
66.
67.
Uday Yanamandra Prateek Deo Kamal Kant Sahu Ram Vasudevan Nampoothiri Nalini Gupta Anusree Prabhakaran Deb Prasad Dhibhar Alka Khadwal Gaurav Prakash Man Upadesh Singh Sachdeva Deepesh Lad Neelam Varma Subhash Varma Pankaj Malhotra 《Clinical Lymphoma, Myeloma & Leukemia》2019,19(3):183-189.e1
Background
Multiple myeloma (MM) is a hematologic malignancy of plasma cell origin. MM primarily affects bone marrow, but extramedullary sites can also be involved. Myelomatous pleural effusion (MPE) is an atypical and rare complication of MM. We aimed to systematically study the incidence and clinicopathologic profile of patients with MPE in a real-world setting.Patients and Methods
In this retrospective study, 415 consecutive patients with MM managed at a tertiary care center in North India during a study period of January 1, 2010 to December 31, 2015 were evaluated for MPE. The patients with MPE were analyzed for their clinical profile, diagnosis, treatment, and outcomes.Results
Of these 415 patients, 11 (2.65%) patients had MPE. The median age of the study population was 50 years with male preponderance. The majority of these patients had immunoglobin (Ig)G Kappa disease. All patients had higher than International Staging System stage I disease. MPE was a presenting feature at MM diagnosis in 45.45% (n = 5) of the patients, whereas the rest developed MPE during follow-up. MPE presented predominantly (81.8%) as a unilateral effusion. Concurrent extramedullary involvement at other site was seen in 45.45% (n = 5), with 3 (27%) patients having concurrent myelomatous ascites. Six of these were managed aggressively, whereas 5 patients opted for palliation. The outcomes were dismal (90.9% mortality), with a median survival of 2.47 months.Conclusion
MPE is a rare entity, and positive outcomes of therapy remain low with dismal prognosis. 相似文献68.
69.
70.
Marie V. Plaisime PhD MPH Marie Jipguep-Akhtar PhD Joseph J. Locascio PhD Harolyn M. E. Belcher MD MHS Rachel R. Hardeman PhD MPH Katherine Picho-Kiroga PhD Sylvia P. Perry PhD Sean M. Phelan PhD MPH Michelle van Ryn PhD LMFT MPH John F. Dovidio PhD 《Health services research》2023,58(Z2):229-237