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991.
Jung-Fa Tsai Wen-Yu Chang Jen-Eing Jeng Mei-Shang Ho Zu-Yau Lin Jeui-Hsiung Tsai 《Liver international》1994,14(2):98-102
To investigate whether hepatitis B virus (HBV) and hepatitis C virus (HCV) infection are risk factors for liver cirrhosis and hepatocellular carcinoma (HCC), a case-control study of 102 cirrhotic HCC patients, 102 sex-matched and age-matched patients with liver cirrhosis, and 102 matched patients with non-hepatic disease controls was performed. The prevalences of hepatitis B surface antigen (HBsAg) and antibody to HCV (anti-HCV) in HCC (70.5%, 39.2%) and liver cirrhosis (74.5%, 27.4%) were higher than controls (16.6%, 10.5%) (P = 0.0001). In HBsAg-negative patients, the prevalence of anti-HCV in cirrhotic HCC (66.6%) and liver cirrhosis (46.1%) was higher than in controls (10.5%; P = 0.0001). There was no such difference in HBsAg-positive patients. Multivariate analysis revealed that both HBsAg and anti-HCV were important risk factors for HCC (odds ratio, 6.52 and 4.59, respectively) and liver cirrhosis (odds ratio, 4.22 and 2.29, respectively). There was no difference in odds ratio when HCC and liver cirrhosis were compared. Our result implies that both HBV and HCV are independent risk factors for cirrhotic HCC and liver cirrhosis in Taiwan. 相似文献
992.
Prostate cancer has become the 7th most common malignancy in Taiwan in 2000. To our knowledge, many diagnostic tests have been developed, including digital rectal examination (DRE), transrectal ultrasound (TRUS), prostate specific antigen (PSA), PSA density (PSAD), PSA velocity, age-specific PSA, and free-to-total PSA, but none of them has been proven to be definitely effective in deciding which person is to receive prostate biopsy. Viewpoints vary with clinician and area. A total of 300 patients over 7-year time period received DRE, TRUS, PSA, and PSAD tests and then had prostate biopsy in Kaohsiung Medical University Hospital. We collect our results and review the literature to find the cost-effectiveness of the tests to prevent unnecessary biopsy and delay in diagnosis. Fifty-two patients (19%) with PSA > 4 ng/ml had prostate cancer. Only 10.5% of patients with prostate cancer had abnormal TRUS lesions, and 20% with prostate cancer showed abnormal DRE results. Because of DRE is non-invasive and inexpensive, we commend the annual use of DRE combined with PSA check in males of 50 years and above to screen for prostate cancer, despite the poor sensitivity of DRE. Therefore, in cases where there is either PSA > 4 ng/ml or abnormal DRE results, it is suggested that patients receive prostate biopsy. There is still no definite conclusion in other diagnostic tests including TRUS. 相似文献
993.
Yi Yin Jan Miin Fu Chen Long Bin Jeng Shin Cheh Chen 《Journal of hepato-biliary-pancreatic sciences》1994,1(2):210-215
Bile duct injury is a serious complication of laparoscopic cholecystectomy, with 50% of bile duct injuries showing a delayed presentation. We experienced four patients (one male and three female) with bile duct injuries after laparoscopic cholecystectomy performed and referred by a local practitioner. The patients' ages ranged from 34 to 63 years. Symptoms included abdominal pain, anorexia, jaundice, ascites, ileus, fever, and tarry stool. Ductal injuries were a result of electrocautery burn in two patients and biliary strictures were due to malapplication of endoclips in the remaining two. The observed bile duct injuries, confirmed by ultrasonography, computed tomography (CT) scanning, and cholangiographic studies, were successfully treated by choledochotomy with a silastic T-tube stent. To avoid bile duct injuries, laparoscopic cholecystectomy should be performed by a well trained and experienced hepatobiliary surgeon, who should ensure accurate identification of the anatomical structures of Calot's triangle, careful dissection and management of intraoperative bleeding, and a lower threshold for conversion to open surgery. 相似文献
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995.
Sixty young Taiwanese women with palpable breast masses detected by mammography and/or physical examinations underwent mammoscintigraphy with thallium-201 (Tl-201) single photon emission computed tomography (SPECT) to assess its value for differentiating breast masses. The results showed that 42 of the 45 cases of breast carcinoma were detected by Tl-201 SPECT mammoscintigraphy. Fourteen of the 15 of benign breast lesions were differentiated by Tl-201 SPECT mammoscintigraphy. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of Tl-201 SPECT mammoscintigraphy were 93%, 93%, 98%, 82%, and 93%, respectively. Thirty-eight of the 45 cases of breast carcinoma were detected by mammography. Twelve of the 15 of benign breast lesions were differentiated by mammography. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of mammography were 84%, 80%, 93%, 63%, and 83%, respectively. We concluded that Tl-201 SPECT mammoscintigraphy significantly improves the accuracy when comparing with mammography for the differentiating breast cancer in Taiwanese women. 相似文献
996.
Apolipoproteins and carotid artery atherosclerosis in an elderly multiethnic population: the Northern Manhattan stroke study 总被引:1,自引:0,他引:1
Jeng JS Sacco RL Kargman DE Boden-Albala B Paik MC Jones J Berglund L 《Atherosclerosis》2002,161(2):317-325
There is accumulating evidence for a role of tumor necrosis factor-alpha (TNF-alpha) in insulin resistance induced by obesity. The purpose of this study was to investigate whether the TNF alpha/G-308A polymorphism was associated with responses to oral glucose and fat tolerance tests in a case--control study comparing male offspring with a paternal history of premature myocardial infarction (cases, n=335) to age-matched controls (n=340) recruited from 14 European university populations. Genotype frequencies did not significantly differ between cases and controls. Among cases, those carrying the A allele exhibited a higher area under the curve for insulin (64.5 vs 55.9 mU h/l, P=0.009), a higher increment between baseline concentration and peak of insulin (63.1 vs 52.8 mU/l, P=0.005) and a greater decrease between peak and insulin at 120 min (49.1 vs 36.8 mU/l, P=0.003) than those with the GG genotype. No such effect was observed in control subjects. No association was observed with response to a fat tolerance test either in cases or in controls. The present results suggest that the TNF alpha/G-308A polymorphism might interact with other susceptibility factors to coronary heart disease to predispose to insulin resistance, and that the ability of TNF-alpha to induce insulin resistance may extend beyond obesity. 相似文献
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998.
999.
Chaewon Kim Jaeyoung Pae Woo Jeng Kim Yuri Jang Jeong Ha Wie In Yang Park Hyun Sun Ko 《Taiwanese journal of obstetrics & gynecology》2021,60(2):273-280
Objectiveto investigate pertussis vaccination rates during pregnancy and the routine recommendation rates by maternity healthcare professionals (HCPs), including influencing factors, in Korea.Materials and methodsTwo different questionnaires were developed and conducted anonymously for pregnant or postpartum women and maternity HCPs in 30 multi-centers. Maternal pertussis vaccination rates and maternity HCPs’ recommendation rates were analyzed. Independent influencing factors were analyzed using multivariate logistic regression analysis, respectively.ResultsThe rate of pertussis vaccination during pregnancy among 466 women was 67%. Among 164 multiparous women, 35.5% received pertussis vaccinations during every pregnancy. However, 27.9% among all pregnant women did not receive information about pertussis and vaccination. The independent influencing factors for maternal pertussis vaccination, given as the tetanus, diphtheria and acellular pertussis (Tdap), were “getting informed” (OR 18.597, 95% CI 11.206–30.861), “informed by OBGYN doctors” (OR 4.426, 95% CI 2.144–9.267), and “metropolitan residence” (OR 3.048, 95% CI 1.419–6.548). Among a total of 373 maternity HCPs, 210 (56.3%) routinely recommended pertussis vaccination, but 21.7% of the total maternity HCP participants did not know the maternal Tdap guideline. The independent factors affecting routine recommendation were the awareness of guideline (OR 9.771, 95% CI 5.227–18.265, p < 0.001) and personal pertussis vaccination within 10 years (OR 3.108, 95% CI 2.377–10.329, p < 0.001). The barriers for routine recommendation were the lack of informational materials (29%), time (25%), and knowledge (23%).ConclusionTo increase pertussis vaccination coverage in pregnant women, more education for maternity HCPs, increase the personal pertussis vaccination rates of HCPs, and informational materials, are needed. 相似文献
1000.
Jin-Ming Wu MD Ting-Chun Kuo MD Ching-Yao Yang MD PhD Pin-Yi Chiang MS Yung-Ming Jeng MD PhD Pei-Hsin Huang MD PhD Yu-Wen Tien MD PhD 《Annals of surgical oncology》2013,20(1):242-249