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81.
82.
Klein D Mercier M Abeilard E Puyraveau M Danzon A Dalstein V Pozet A Guizard AV Henry-Amar M Velten M 《Breast cancer research and treatment》2011,129(1):125-134
Population-based studies on quality of life (QOL) of long-term breast cancer survivors are quite recent and insufficient attention
has been paid to the effect of time since diagnosis. We compared long-term QOL of population-based breast cancer survivors
5, 10, and 15 years after diagnosis with that of healthy controls. Breast cancer survivors were randomly selected from three
population-based cancer registries (Bas-Rhin, Calvados and Doubs, France) along with healthy controls, stratified for age
and place of residence, randomly selected from electoral rolls. Participants completed five self-administered questionnaires:
the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), Short
Form-36 (SF-36), Spielberger State-Trait Anxiety Inventory (STAI), Multidimensional Fatigue Inventory (MFI) and a life conditions
questionnaire. An analysis of variance was used to compare QOL scores of breast cancer survivors by period (5, 10, or 15 years)
of diagnosis with those of controls, adjusted for sociodemographic data and comorbidities. Six hundred and fifty-two cases
and 1,188 controls participated in the study. For many QOL scales, scores were significantly different between cancer survivors
and controls. A clinically significant difference was evidenced for the fatigue scales, the SF36 physical functioning, role-physical,
and role-emotional scales, with more favorable results for controls. Differences decreased with time and 15-year cancer survivors
were generally not different from controls. Scores were particularly influenced by age and mean household income. More efforts
should be made, specifically during the first 5 to 10 years after diagnosis, to help women with breast cancer to overcome
their impairment in QOL. 相似文献
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84.
N. Le Stang A. Belot A. Gilg Soit Ilg P. Rolland P. Astoul S. Bara P. Brochard A. Danzon P. Delafosse P. Grosclaude A.‐V. Guizard E. Imbernon B. Lapôtre‐Ledoux K. Ligier F. Molinié J.‐C. Pairon E.‐A. Sauleau B. Trétarre M. Velten N. Bossard M. Goldberg G. Launoy F. Galateau‐Sallé 《International journal of cancer. Journal international du cancer》2010,126(1):232-238
The evolution of pleural cancers and malignant pleural mesothelioma incidence in France between 1980 and 2005 was analysed using data derived from the French network of cancer registries (FRANCIM) and the French National Mesothelioma Surveillance Program (PNSM). Mesothelioma proportions in pleural cancers were calculated by diagnosis year in the 1980–2000 period. Our results suggest that the incidences of pleural cancer and mesothelioma levelled off in French men since 2000 and continued to increase in French women. A decrease of the annual pleural cancer incidence average in men was noticed (?3.4% of annual rate of change) between 2000 and 2005. The proportion of pleural cancers that were mesothelioma was unchanged between 1980 and 2003 with an average of 86%. The age standardised incidence rate of pleural mesothelioma remained relatively stable between 1998 and 2005 with a slight falling trend. For women, the age standardised incidence rate of pleural cancers and mesothelioma increased during the period 1998–2005. Additionally, the proportion of pleural cancers that were mesothelioma increased during the same period of time. Finally, the increased trend observed in the incidence of pleural mesothelioma and cancers in women is credibly due to their under diagnosis in the 1980–1997 period. The comparison between the French incidence and the American and British ones shows that the decreasing trend in incidence of mesothelioma and pleural cancers in French men since 2000 is potentially associated with a lower amphibole consumption and by the implementation of safety regulations at work from 1977. 相似文献
85.
Abstract: Until recently, little attention has been directed towards the role the toothbrush may play in human health, even though a report of toothbrush as a significant factor in the infection appeared in 1920. It is common knowledge that the human mouth harbours a wide variety of microorganisms, some of which, at any given time, can be assumed to be potential pathogens. This was not known when toothbrushes were originally designed, yet the common toothbrush has been used in basically the same form for about 200 years. In today's world of organ transplantation and alteration of the immune system, it is important to consider the toothbrush as a source of potential pathogens. Given the fact that very often people will traumatize themselves with their toothbrush, this trauma may become a potential portal of entry for organisms. In this article, we have attempted to demonstrate the importance of toothbrush disinfection, given tips on home toothbrush care and hope to motivate the dentists to educate the patients on the importance of toothbrush disinfection. 相似文献
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87.
Benoît Piégu Sébastien Guizard Tatsinda Spears Corinne Cruaud Arnault Couloux Dennis K. Bideshi Brian A. Federici Yves Bigot 《Archives of virology》2014,159(5):1181-1185
Members of the family Iridoviridae are animal viruses that infect only invertebrates and poikilothermic vertebrates. Invertebrate iridovirus 25 (IIV-25) was originally isolated from the larva of a blackfly (Simulium spp., order Diptera) found in the Ystwyth river near Aberystwyth, Wales. IIV-25 virions are icosahedral, have a diameter of ~130 nm, and contain a dsDNA genome of 204.8 kbp, with a G+C content of 30.32 %, that codes for 177 proteins. Here, we describe the complete genome sequence of this virus and its annotation. This is the fifth genome sequence of an invertebrate iridovirus reported. 相似文献
88.
Fine‐mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia 下载免费PDF全文
Catherine Tcheandjieu Fabienne Lesueur Marie Sanchez Dominique Baron‐Dubourdieu Anne‐Valerie Guizard Claire Mulot Pierre Laurent‐Puig Claire Schvartz Pascal Guenel 《International journal of cancer. Journal international du cancer》2016,139(3):617-627
Incidence of differentiated thyroid carcinoma varies considerably between countries and ethnic groups, with particularly high incidence rates in Melanesians of New Caledonia. Differentiated thyroid cancer (DTC) has a familial relative risk higher than other cancers, highlighting the contribution of inherited factors to the disease. Recently, genome‐wide association studies (GWAS) identified several DTC susceptibility loci. The most robust associations were reported at loci 9q22 (rs965513 and rs1867277) and 14q13 (rs944289 and rs116909734). In this study, we performed a fine‐mapping study of the two gene regions among Europeans and Melanesians from Metropolitan France and New Caledonia. We examined 81 single nucleotide polymorphisms (SNPs) at 9q22 and 561 SNPs at 14q13 in Europeans (625 cases/776 controls) and in Melanesians (244 cases/189 controls). The association with the four SNPs previously identified in GWAS was replicated in Europeans while only rs944289 was replicated in Melanesians. Among Europeans, we found that the two SNPs previously reported at 9q22 were not independently associated to DTC and that rs965513 was the predominant signal; at 14q13, we showed that the haplotype rs944289[C]‐rs116909374[C]‐rs999460[T] was significantly associated with DTC risk and that the association with rs116909374 differed by smoking status (p‐interaction = 0.03). Among Melanesians, a new independent signal was observed at 14q13 for rs1755774 which is strongly correlated to rs2787423; this latter is potentially a functional variant. Significant interactions with parity (p < 0.05) and body mass index were observed for rs1755774 and rs2787423. This study contributed to a better characterization of the DTC loci 9q22 and 14q13 in Europeans and in Melanesians and has identified novel variants to be prioritized for further functional studies. 相似文献
89.
Trends in the risk of second primary cancer among bladder cancer survivors: a population‐based cohort of 10 047 patients 下载免费PDF全文
90.