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Carbon quantum dots (CQDs) have emerged as potential alternatives to classical metal-based semiconductor quantum dots (QDs) due to the abundance of their precursors, their ease of synthesis, high biocompatibility, low cost, and particularly their strong photoresponsiveness, tunability, and stability. Light is a versatile, tunable stimulus that can provide spatiotemporal control. Its interaction with CQDs elicits interesting responses such as wavelength-dependent optical emissions, charge/electron transfer, and heat generation, processes that are suitable for a range of photomediated bioapplications. The carbogenic core and surface characteristics of CQDs can be tuned through versatile engineering strategies to endow specific optical and physicochemical properties, while conjugation with specific moieties can enable the design of targeted probes. Fundamental approaches to tune the responses of CQDs to photo-interactions and the design of bionanoprobes are presented, which enable biomedical applications involving diagnostics and therapeutics. These strategies represent comprehensive platforms for engineering multifunctional probes for nanomedicine, and the design of QD probes with a range of metal-free and emerging 2D materials.
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Kalashnyk  Nataliya  Ledieu  Julian  Gaudry  Émilie  Cui  Can  Tsai  An-Pang  Fournée  Vincent 《Nano Research》2018,11(4):2129-2138
Nano Research - The formation of long-range ordered aperiodic molecular films on quasicrystalline substrates is a new challenge that provides an opportunity for further surface functionalization....  相似文献   
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Asymmetric tensor field visualization can provide important insight into fluid flows and solid deformations. Existing techniques for asymmetric tensor fields focus on the analysis, and simply use evenly-spaced hyperstreamlines on surfaces following eigenvectors and dual-eigenvectors in the tensor field. In this paper, we describe a hybrid visualization technique in which hyperstreamlines and elliptical glyphs are used in real and complex domains, respectively. This enables a more faithful representation of flow behaviors inside complex domains. In addition, we encode tensor magnitude, an important quantity in tensor field analysis, using the density of hyperstreamlines and sizes of glyphs. This allows colors to be used to encode other important tensor quantities. To facilitate quick visual exploration of the data from different viewpoints and at different resolutions, we employ an efficient image-space approach in which hyperstreamlines and glyphs are generated quickly in the image plane. The combination of these techniques leads to an efficient tensor field visualization system for domain scientists. We demonstrate the effectiveness of our visualization technique through applications to complex simulated engine fluid flow and earthquake deformation data. Feedback from domain expert scientists, who are also co-authors, is provided.  相似文献   
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Why would people use Short Message Service (SMS) to say something they would not say in person? There is a trend that SMS is becoming more and more popular because it facilitates more extended modes of communications. Using technology acceptance model, we hypothesize the attitude of SMS would be influenced by its perceived effectiveness for communications, perceived ease of use, and subjective norm. Besides the special aspects of communications, conflict avoidance and privacy protection will enforce the impact of perceived effectiveness of SMS for communication. We investigated 953 SMS users and the results support most of our hypotheses. Furthermore, our analyses also show there are differences between females and males on the influence mechanism behind their attitude towards SMS.  相似文献   
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We introduce a new geometric method to generate sphere packings with restricted overlap values. Sample generation is an important, but time-consuming, step that precedes a calculation performed with the discrete element method (DEM). At present, there does not exist any software dedicated to DEM which would be similar to the mesh software that exists for finite element methods (FEM). A practical objective of the method is to build very large sphere packings (several hundreds of thousands) in a few minutes instead of several days as the current dynamic methods do. The developed algorithm uses a new geometric procedure to position very efficiently the polydisperse spheres in a tetrahedral mesh. The algorithm, implemented into YADE-OPEN DEM (open-source software), consists in filling tetrahedral meshes with spheres. In addition to the features of the tetrahedral mesh, the input parameters are the minimum and maximum radii (or their size ratio), and the magnitude of authorized overlaps. The filling procedure is stopped when a target solid fraction or number of spheres is reached. Based on this method, an efficient tool can be designed for DEMs used by researchers and engineers. The generated packings can be isotropic and the number of contacts per sphere is very high due to its geometric procedure. In this paper, different properties of the generated packings are characterized and examples from real industrial problems are presented to show how this method can be used. The current C++ version of this packing algorithm is part of YADE-OPEN DEM [20] available on the web (https://yade-dem.org).  相似文献   
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The performance evaluation is regarded as a multiple criteria decision making (MCDM) problem and has a significant impact on the operations of the enterprise. This paper develops an integrated MCDM approach that combines the voting method and the fuzzy TOPSIS (technique for order preference by similarity to ideal solution) method to evaluate the performance of multiple manufacturing plants in a fuzzy environment. Fuzzy TOPSIS helps decision-makers carry out analysis and comparisons in ranking their preference of the alternatives with vague or imprecise data. Since the evaluation result is often greatly affected by the weights used in the evaluation process, the voting method is used in this study to determine the appropriate criteria weights. A case study demonstrating the applicability of the proposed model is presented. The case company is the world’s largest manufacturer of power supplies. It has three primary manufacturing bases located in Wujiang, Dongguan, and Tianjin, China. The proposed approach is used to evaluate the performance of the company’s five manufacturing plants in Wujiang, which produce switch power, telecom power, DC/DC converters, uninterruptible power systems (UPS) and AC/DC adapters.  相似文献   
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This paper proposes a novel fault tolerant control (FTC) scheme for hybrid systems modeled by hybrid Petri nets (HPNs). The HPNs model consists of discrete and continuous PNs. The faults are represented by unobservable discrete transitions or the normal observable discrete transitions with abnormal firing time in discrete PNs. First, an observer‐based fault diagnosis method is proposed to estimate the marking in discrete places with unknown initial marking and diagnose the faulty behavior simultaneously. Then, an adaptive fault tolerant controller is designed to maintain the general mutual exclusion constraints (GMEC) of discrete PNs, and a scheme that adjusts firing speeds of continuous transitions is provided to maintain the optimality of continuous PNs. Finally, an example of an intelligent transportation system consisting of automated vehicles on a bridge is included to demonstrate the effectiveness of our developed techniques. Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society  相似文献   
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