The significance of gastric helicobacteriosis in the genesis hemorrhage from duodenal peptic ulcer

Based on a comprehensive analysis of findings from examination and surgical treatment of 196 patients with bleeding pyloroduodenal ulcers, it was found out that patients with concurrent helicobacteriosis of the stomach are prone to more unfavourable course of their illness, which fact is evidenced by a greater loss of blood and higher risk for bleeding recurrences. A classification is proposed by the authors, taking advantage of the data from endoscopic, microscopic and immunoenzymatic techniques, with the purpose of providing an assessment of degree of severity of helicobacteriosis of the stomach.     

Passive care and active rehabilitation in a patient with failed back surgery syndrome

Blood-borne cytokines enter the brain by transport across the blood-brain barrier (BBB) or by leakage through extracellular pathways at sites, such as circumventricular organs (CVOs), without a BBB. We used radioactively labeled albumin (T-Alb) to differentiate the relative contribution of transport and extracellular pathways to the passage of interleukin-1 alpha ([125I]IL-1 alpha) across the BBB. The major mechanism of entry for [125I]IL-1 alpha after intravenous (i.v.) injection was a saturable transport system with extracellular pathways accounting for only a small fraction of entry into brain. CVOs concentrated blood-borne [125I]IL-1 alpha in a saturable manner to a much greater extent than did the cerebral cortex and cerebellum, but accounted for less that 5% of total brain uptake. After intracerebroventricular (i.c.v.) injection, [125I]IL-1 alpha and T-Alb were concentrated in the CVOs, especially the median eminence, although CVOs contained less that 1% of the substances injected. Distribution after i.c.v. injection was largely due to diffusion and leakage through extracellular pathways. We conclude that after i.c.v. injection, leakage across extracellular pathways accounts for the small but concentrated amount of [125I]IL-1 alpha found in CVOs. After i.v. injection, transport across the BBB accounts for the majority of [125I]IL-1 alpha in brain.     

基于SOC的PAGER控制芯片设计

文章讨论了PAGER控制器芯片（ZQD021）的系统设计，该控制器内部集成了FLASH，SRAM，POCSAG协议解码器和嵌入式MCU CORE。重点分析了芯片的可测性设计（DFT），内嵌FLASH设计，低功耗设计，其设计方法和思路对消费类和嵌入式控制芯片的设计有一定的借鉴意义。     

一种基于波束-频域处理的自适应波束形成方法

在天波超视距雷达中 ,通道之间的频响不一致影响了自适应波束形成的性能。去斜处理使得不同距离对应于不同频率 ,故不同距离单元的幅相不一致性与不同的频率相对应。经距离维FFT处理后 ,各路之间的通道不一致性得到降低 ,带内起伏趋于固定。基于上述特性 ,本文提出一种波束 频域处理方法 ,该方法不仅有效对消干扰 ,同时不会恶化天线方向图。更重要的是该方法降低了处理维数 ,减少了计算的复杂度。     

Prevalence and risk factors in serous arthritis in the carpal joint of Norwegian coldblooded trotters

Of 508 four-year-old coldblooded trotters examined for carpitis, 135 (27%) had the condition. Thirty horses had unilateral carpitis on the left frontlimb, 52 on the right frontlimb and 53 had bilateral carpitis. Of these horses, 105 were stallions, 135 were geldings and 269 were mares. The prevalence of carpitis in these three groups was 25%, 25% and 28%, respectively. Information was obtained on the training regimes in four periods of the life of 378 horses. The odds ratios for the training variables were of the same order in all four periods. In logistic regression analyses on the training variables for the first period for the variable percentage of carpitis within each progeny group (sire index), the odds ratio corresponding to a 10% increase in sire index was 1.7 (1.4, 2.1) (95% confidence interval of the odds ratio). The odds ratios for leaving the horses out in a paddock, walking in a jogcart and fast training, or not in each case, were 0.4 (0.2, 0.9), 2.5 (1.2, 5.3) and 2.0 (0.9, 4.4), respectively. This implies a decreased risk of developing carpitis for horses left out in a paddock as a two-year-old, and a 2.5 and 2.0 times increased risk of carpitis occuring in horses exposed to walking in a jogcart and fast training, respectively. Information on the feeding regimes during the first, second and third year collected by a questionnaire revealed no association with carpitis beyond that which could be ascribed to chance. The rations offered were within normal ranges except for calcium, which was below recommended levels.     

Regulation of organelle movement in melanophores by protein kinase A (PKA), protein kinase C (PKC), and protein phosphatase 2A (PP2A)

We used melanophores, cells specialized for regulated organelle transport, to study signaling pathways involved in the regulation of transport. We transfected immortalized Xenopus melanophores with plasmids encoding epitope-tagged inhibitors of protein phosphatases and protein kinases or control plasmids encoding inactive analogues of these inhibitors. Expression of a recombinant inhibitor of protein kinase A (PKA) results in spontaneous pigment aggregation. alpha-Melanocyte-stimulating hormone (MSH), a stimulus which increases intracellular cAMP, cannot disperse pigment in these cells. However, melanosomes in these cells can be partially dispersed by PMA, an activator of protein kinase C (PKC). When a recombinant inhibitor of PKC is expressed in melanophores, PMA-induced pigment dispersion is inhibited, but not dispersion induced by MSH. We conclude that PKA and PKC activate two different pathways for melanosome dispersion. When melanophores express the small t antigen of SV-40 virus, a specific inhibitor of protein phosphatase 2A (PP2A), aggregation is completely prevented. Conversely, overexpression of PP2A inhibits pigment dispersion by MSH. Inhibitors of protein phosphatase 1 and protein phosphatase 2B (PP2B) do not affect pigment movement. Therefore, melanosome aggregation is mediated by PP2A.     

一种基于数据竞争的高分辨率图像的聚类分割算法

近些年,机器人技术得到了迅猛的发展,应用越来越广泛.随着机器人技术的推广和普及,对机器人使用的要求也越来越高,其中对智能机器人的要求尤显迫切.机器视觉是智能机器人研究领域的一个重要研究方向.在机器人视觉系统中,核心问题是目标提取,对目标实时、准确、快速提取的关键技术是图像分割.由于机器人感知的环境的复杂性及目标的多样性,往往导致机器人感知获得的图像数据量较大且图像本身存在不可预知的复杂性,这就对准确的目标分割和提取处理提出了挑战性问题.本文针对高分辨率图像数据集的分割处理,提出一种新的聚类算法,即根据数据点能量和的大小识别类代表点和类成员点,通过数据点间的竞争识别出最有能力成为簇成员的数据点,并将其与mean shift聚类算法有效地结合应用于彩色图像分割问题中,能够快速高效地实现高分辨率图像的目标分割,并得到较好的图像分割效果.实验结果表明,本文算法在分割效果和分割效率上明显优于传统聚类算法.     

基于非下采样Contourlet变换的指纹图像超分辨率重建

非下采样Contourlet变换(Nonsubsampled contourlet transform,NSCT)采用非抽样金字塔结构和非抽样方向滤波器组构成,具有Contourlet变换所不具备的平移不变性、较高冗余度等优良特性,而且能够克服伪吉布斯现象。图像经过非下采样Contourlet变换后分解成多尺度、多方向的细节信息,这些细节信息代表了图像不同频带不同方向的特征,这就简化了系数之间的关系。基于学习的超分辨率重建算法具有整体的预测性,将非下采样Contourlet变换和基于学习的算法相结合,在一定程度上提高训练精度。针对指纹图像的实验证明该算法具有良好的性能,重建的图像纹理性细节信息较好,基本保持了原指纹图像的特征点,更接近于原始的高分辨率图像。     

科学家、组织与技术及其关系的社会网络分析

社会网络分析能够对社会网络中行为者之间的关系进行量化分析,以可视化的图形界面展示节点之间的深层关系及群体结构。本文从维基百科中采集计算机网络领域内前沿网络技术、突出贡献科学家和学术信息权威组织机构的相应信息,构建网络技术与科学家、组织机构与科学家等多种类型的关系网络,从中心性、凝聚性及核心-边缘结构等方面进行社会网络分析,得到热点技术、核心研究团队等计算机网络发展趋势上的若干特征。