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The demand for biofuels and biochemicals is expected to increase in the future, which will in turn increase the demand for biomass feedstock. Large gasification plants fueled with biomass feedstock are likely to be a key enabling technology in a resource‐efficient, bio‐based economy. Furthermore, the costs for producing biofuels and biochemicals in such plants could potentially be decreased by utilizing inexpensive low‐grade residual biomass as feedstock. This study investigates the usage of shredded tree bark as a feedstock for the production of biomethane in the GoBiGas demonstration plant in Gothenburg, Sweden, based on a 32 MWth industrial dual fluidized bed gasification unit. The plant was operated with bark feedstock for 12 000 hours during the period 2014 to 2018. Data from the measurement campaign were processed using a stochastic approach to establish the plant's mass and energy balances, which were then compared with operation of the plant with wood pellets. For this comparison, an extrapolation algorithm was developed to predict plant performance using bark dried to the same moisture content as wood pellets, ie, 8%w.b. Plant operation with bark feedstock was evaluated for operability, efficiency, and feedstock‐related cost. The gas quality achieved during the test period was similar to that obtained for operation with wood pellets. Furthermore, no significant ash sintering or agglomeration problems were observed more than 750 hours of operation. The calculated biomass‐to‐biomethane efficiency is 43% to 47% (lower heating value basis) for operation with wet bark. However, the predicted biomass‐to‐biomethane efficiency can be increased to 55%–65% for operation with bark feedstock dried to 8% moisture content, with corresponding feedstock costs in the range of 24.2 to 32.7 EUR/MWh; ie, a cost reduction of about 40% compared with wood pellets.  相似文献   
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Lyhagen  Johan  Ahlgren  Per 《Scientometrics》2020,125(3):2545-2560
Scientometrics - Journal rankings often show significant changes compared to previous rankings. This gives rise to the question of how well estimated the rank of a journal is. In this contribution,...  相似文献   
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In this paper, we are exploring the approach to utilize system-specific static analyses of code with the goal to improve software quality for specific software systems. Specialized analyses, tailored for a particular system, make it possible to take advantage of system/domain knowledge that is not available to more generic analyses. Furthermore, analyses can be selected and/or developed in order to best meet the challenges and specific issues of the system at hand. As a result, such analyses can be used as a complement to more generic code analysis tools because they are likely to have a better impact on (business) concerns such as improving certain software quality attributes and reducing certain classes of failures. We present a case study of a large, industrial embedded system, giving examples of what kinds of analyses could be realized and demonstrate the feasibility of implementing such analyses. We synthesize lessons learned based on our case study and provide recommendations on how to realize system-specific analyses and how to get them adopted by industry.  相似文献   
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We developed a computer program for use in undergraduate and graduate courses in pharmacology, pharmacokinetics and pharmacodynamics. This program can also be used in environmental and toxicological studies and preclinical simulation, to facilitate communication between modeling pharmacokineticists and project leaders or other decision-makers in the pharmaceutical industry. The program simulates the drug delivery and transport by means of (I) a six-compartment physiological pharmacokinetic flow model, (II) a system of traditional compartment models, or (III) a target-mediated drug disposition system. The program also can be used to simulate instantaneous equilibria between concentration and pharmacodynamic response, or as temporal delays between concentration and response. The latter is done by means of turnover models (indirect response models). Drug absorption, distribution, and elimination are represented by differential equations, which are described by organ and tissue volumes or other volumes of distribution, blood flows, clearance terms, and tissue-to-blood partition coefficients. The user can control and adjust these parameters by means of a slider in real time. By interactively changing the parameter values and simultaneously displaying the resulting concentration–time and/or response–time profiles, users can understand the major mechanisms that govern the disposition or the pharmacological response of the drug in the organism in real time. Schedule dependence is typically seen in clinical practice with a non-linear concentration–response relationship, and is difficult to communicate except via simulations. Here, we sought to illustrate the potential advantages of this approach in teaching pharmacology, pharmacokinetics, and pharmacodynamics to undergraduate pharmacy-, veterinary-, and medical students or to project teams in drug discovery/development.  相似文献   
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Unripe banana flour is a potential commercial ingredient in various food products for increased resistant starch and reduced gluten contents. In the present study, the pasting (rapid visco-analysis), gel texture (penetration test), thermal (differential scanning calorimetry), colour (tri-stimulus colour indices) and the resistant starch properties of unripe banana flour produced from different dessert banana varieties (n?=?10) cultivated in South Africa, were analysed and juxtaposed to wheat and maize flour. The functional properties varied significantly (p?≤?0.05) between banana varieties, and from wheat and maize flours, to various extents. Selected functional property ranges of unripe banana, wheat and maize flours, respectively included; flour colour index (63.16–76.42, 77.34 and 80.96), paste viscosity (405.5–556.6, 124.7 and 115.6 RVU), gelatinization temperature (64.67–71.21, 71.11 and 69.95?°C), gel firmness (7.24–11.44?×?10??2 N, 3.49?×?10??2 N and 6.56?×?10??2 N) and resistant starch content (19.9–47.4, 2.8 and 2.2% w/w). Multivariate analysis (principle component analysis) showed that the unripe banana flours from different varieties were distinguished from each other based on the pasting temperature. The unripe banana flours were distinguished from both wheat and maize flour based on breakdown and peak paste viscosities. The breakdown viscosity was the most positively related measure to the resistant starch content with a linear regression R-squared value of 0.898, indicating a significant role played by granule structure in resistance to enzymatic hydrolysis. The present research demonstrates that selection of appropriate dessert banana variety is important when replacing staple flours (wheat and maize) with unripe dessert banana flour as a functional ingredient.  相似文献   
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In this study, teachers' acceptance and use of an educational portal is assessed based on data from two sources: usage data (number of logins, downloads, uploads, reactions and pages viewed) and an online acceptance questionnaire. The usage data is extracted on two occasions from the portal's database: at survey completion (T1) and twenty-two months later (T2). Framework for this study is C-TAM-TPB (Combined Technology Acceptance Model and Theory of Planned Behavior). 919 usable responses from teachers are obtained. Based on the observed use data at T1, four types of portal users are distinguished: ‘new’ (N = 37), ‘light’ (N = 641), ‘medium’ (N = 201), and ‘heavy’ (N = 40). Path analyses show that all predictor variables in C-TAM-TPB influence teachers' portal acceptance, but their significance level varies depending on the user type. The strongest predictors of behavioral intention to use the portal are attitude (‘new’) and perceived usefulness (‘light’, ‘medium’ and ‘heavy’), with variance explained ranging from .39 (‘medium’) to .71 (‘heavy’). The observed use data show that the portal is primarily used to search for and download material, rather than for sharing material or information. The use data at T2 show that teachers become more efficient in their search behavior and that the majority of the teachers use the portal more frequently. Guidelines are proposed to policymakers and school boards aiming to introduce a similar technology to teachers.  相似文献   
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