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991.
Ala I Sharara Ali H Harb Fayez S Sarkis Jean M Chalhoub Rami Badreddine Fadi H Mourad Mahmoud Othman Omar Masri 《World journal of gastroenterology : WJG》2015,21(6):1938-1944
AIM:To compare the efficacy and palatability of 4L polyethylene glycol electrolyte(PEG)plus sugar-free menthol candy(PEG+M)vs reduced-volume 2 L ascorbic acid-supplemented PEG(Asc PEG).METHODS:In a randomized controlled trial setting,ambulatory patients scheduled for elective colonoscopy were prospectively enrolled.Patients were randomized to receive either PEG+M or Asc PEG,both splitdosed with minimal dietary restriction.Palatability was assessed on a linear scale of 1 to 5(1=disgusting;5=tasty).Quality of preparation was scored by assignment-blinded endoscopists using the modified Aronchick and Ottawa scales.The main outcomes were the palatability and efficacy of the preparation.Secondary outcomes included patient willingness to retake the same preparation again in the future and completion of the prescribed preparation.RESULTS:Overall,200 patients were enrolled(100patients per arm).PEG+M was more palatable than Asc PEG(76%vs 62%,P=0.03).Completing the preparation was not different between study groups(91%PEG+M vs 86%Asc PEG,P=0.38)but more patients were willing to retake PEG+M(54%vs 40%respectively,P=0.047).There was no significant difference between PEG+M vs Asc PEG in adequate cleansing on both the modified Aronchick(82%vs77%,P=0.31)and the Ottawa scale(85%vs 74%,P=0.054).However,PEG+M was superior in the left colon on the Ottawa subsegmental score(score0-2:94%for PEG+M vs 81%for Asc PEG,P=0.005)and received significantly more excellent ratings than Asc PEG on the modified Aronchick scale(61%vs 43%,P=0.009).Both preparations performed less well in afternoon vs morning examinations(inadequate:29%vs 15.2%,P=0.02).CONCLUSION:4 L PEG plus menthol has better palatability and acceptability than 2 L ascorbic acidPEG and is associated with a higher rate of excellentpreparations;Clinicaltrial.gov identifier:NCT01788709. 相似文献
992.
Hussain Bahbahani Khaled Aljenaee Abdelhaleem Bella 《Journal of the Saudi Heart Association》2015,27(1):57-60
Acute myocardial infarction (AMI) is usually seen in the setting of atherosclerosis and its associated risk factors. Myocardial infarction in the young poses a particular challenge, as the disease is less likely, due to atherosclerosis. We report the case of a 37-year-old female patient who presented with ST segment elevation anterolateral AMI. The only abnormality on routine blood investigation was raised hemoglobin and hematocrit. After further testing, she was diagnosed according to the World Health Organization (WHO) criteria with polycythemia vera. This case illustrates the importance of recognizing polycythemia vera as an important cause of thrombosis, which can present initially as AMI, and to emphasize the early recognition of the disease in order to initiate appropriate management strategies. 相似文献
993.
Khaled Baqais Meagan Mahoney Kathleen Tobler Anita Hui Mary Noseworthy 《Canadian respiratory journal》2015,22(5):261-262
Sand aspiration is a rare but potentially fatal occurrence to consider in near-drownings, accidental burials or cave-ins. Optimal management is not well defined. 相似文献
994.
Mahmoud H. Mosli Othman Al-Harbi Brian G. Feagan Majid A. Almadi 《Saudi Journal Of Gastroenterology》2015,21(4):185-197
The objective of this position statement from the Saudi Gastroenterology Association is to guide gastroenterologists on the use of tumor necrosis factor-alfa (TNF-α) antagonists for the treatment of the idiopathic inflammatory bowel diseases, Crohn''s disease, and ulcerative colitis. In this article, we summarize the relevant literature regarding the safety and efficacy of TNF-α antagonists, highlight relevant safety concerns specific to the environment in Saudi Arabia, and provide specific recommendations for the use of these agents. 相似文献
995.
Laxmi Kokatnur Mohan Rudrappa Khaled R. Khasawneh 《Annals of Indian Academy of Neurology》2015,18(2):252-255
Cerebral fat embolism (CFE) is an uncommon but serious complication following orthopedic procedures. It usually presents with altered mental status, and can be a part of fat embolism syndrome (FES) if associated with cutaneous and respiratory manifestations. Because of the presence of other common factors affecting the mental status, particularly in the postoperative period, the diagnosis of CFE can be challenging. Magnetic resonance imaging (MRI) of brain typically shows multiple lesions distributed predominantly in the subcortical region, which appear as hyperintense lesions on T2 and diffusion weighted images. Although the location offers a clue, the MRI findings are not specific for CFE. Watershed infarcts, hypoxic encephalopathy, disseminated infections, demyelinating disorders, diffuse axonal injury can also show similar changes on MRI of brain. The presence of fat in these hyperintense lesions, identified by MR spectroscopy as raised lipid peaks will help in accurate diagnosis of CFE. Normal brain tissue or conditions producing similar MRI changes will not show any lipid peak on MR spectroscopy. We present a case of CFE initially misdiagnosed as brain stem stroke based on clinical presentation and cranial computed tomography (CT) scan, and later, MR spectroscopy elucidated the accurate diagnosis. 相似文献
996.
Mahmoud Torabinejad Ali Nosrat Prashant Verma Oyoyo Udochukwu 《Journal of endodontics》2017,43(11):1806-1820
Introduction
A mineral trioxide aggregate (MTA) apical plug (MAP) and regenerative endodontic treatment (RET) have shown acceptable clinical outcomes. However, comparative studies are scarce. The aims of this study were to examine the level of evidence for both treatments, conduct a systematic review of the literature on MAP and RET, and run a meta-analysis on the survival and success rates of teeth treated with these procedures.Methods
Electronic searches were performed in MEDLINE, Web of Science, and the Cochrane Library. Two authors independently screened the titles and abstracts for eligibility. Subgroup analyses were performed on the clinical outcomes (ie, survival and success) of the procedures.Results
In all, 750 studies were identified, and 144 studies were subjected to qualitative synthesis. Ten randomized clinical trials were included in subgroup analyses. Most of the studies in both groups were case reports and case series (72% and 86% in MAP and RET, respectively). The overall level of evidence in both groups was low. The pooled survival rates were 97.1% (95% confidence interval [CI], 93.7–100) and 97.8% (95% CI, 94.8–100) for MAP and RET, respectively. The pooled success rates were 94.6% (95% CI, 90.2–99.1) and 91.3% (95% CI, 84.5–98.2) for MAP and RET, respectively. Very little heterogeneity was observed among the studies regarding survival and success rates (I2 < 50%, P > .10). There was no significant difference between the 2 groups regarding survival (P = 1.00) or success rates (P = .58).Conclusions
The existing literature lacks high-quality studies with a direct comparison of outcomes of MAP and RET. Randomized multicenter clinical trials with large sample sizes and long-term follow-ups are needed to address this gap in knowledge. 相似文献997.
998.
Eugene H. Chang MD Xiao Xiao Tang PhD Viral S. Shah BA Janice L. Launspach RN CCRC Sarah E. Ernst BS Brieanna Hilkin BS Philip H. Karp BS Mahmoud H. Abou Alaiwa MD Scott M. Graham MD Douglas B. Hornick MD Michael J. Welsh MD David A. Stoltz MD PhD Joseph Zabner MD 《International forum of allergy & rhinology》2015,5(2):178-181
999.
1000.
Andrew Redfern Huda Mahmoud Tom McCulloch Adam Shardlow Matthew Hall Catherine Byrne Nicholas M. Selby 《Clinical journal of the American Society of Nephrology》2015,10(2):180-186