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641.
Neurons selective for binocular disparity are found in a number of visual cortical areas in primates, but there is little evidence that any of these areas are specialized for disparity processing. We have examined the organization of disparity-selective neurons in the middle temporal visual area (MT), an area shown previously to contain an abundance of disparity-sensitive neurons. We recorded extracellularly from MT neurons at regularly spaced intervals along electrode penetrations that passed through MT either normal to the cortical surface or at a shallow oblique angle. Comparison of multiunit and single-unit recordings shows that neurons are clustered in MT according to their disparity selectivity. Across the surface of MT, disparity-selective neurons are found in discrete patches that are separated by regions of MT that exhibit poor disparity tuning. Within disparity-selective patches of MT, we typically observe a smooth progression of preferred disparities (e.g. , near to far) as our electrode travels parallel to the cortical surface. In electrode penetrations normal to the cortical surface, on the other hand, MT neurons generally have similar disparity tuning, with little variation from one recording site to the next. Thus disparity-tuned neurons are organized into cortical columns by preferred disparity, and preferred disparity is mapped systematically within larger, disparity-tuned patches of MT. Combined with other recent findings, the data suggest that MT plays an important role in stereoscopic depth perception in addition to its well known role in motion perception. 相似文献
642.
A published procedure for the liquid-liquid extraction of Cd by sodium diethyldithiocarbamate (NaDDC) was modified and tested on 12 biological matrixes of plant and animal origin for use with isotope dilution (ID) inductively coupled plasma mass spectrometry (ICPMS). The tested matrixes were reference materials, certified for Cd, and a feces in-house standard. The digested and extracted standards were analyzed for Cd stable isotopes by ICPMS and the resulting isotope ratios examined for isobaric and polyatomic interferences. Cadmium recoveries, after extraction, ranged from 73% to 20% and apparently were inversely related to Cd concentration, even in the presence of excess chelator. For each reference material, the measured isotope ratios for Cd were corrected for instrumental bias and compared to natural abundance Cd isotope ratios. Nonextracted samples had large isotope ratio deviations for all but one or two ratios. Extraction improved all the isotope ratios measured (lowered % error relative to natural abundances), but interferences were noted for a few samples. The extracted human in-house feces standard was found to have Sn signals reduced by 300-fold, but residual Sn concentrations still interfered with 116Cd, though not 112Cd or 114Cd. Thus, evaluation of the NADDC-extracted in-house fecal standard and reference materials indicate the successful removal of interferences that otherwise prevented accurate determinations of Cd by IDICPMS and show that a number of Cd isotope ratios could be accurately measured (< 1.5% error) for multiple stable isotope tracer studies in a broad range of NaDDC-extracted biological matrixes. 相似文献