超低密度硬胶极压型油包水乳化钻井液在广安002-H9井的应用

在超低密度钻井液的使用方面，传统的油基钻井液和油包水钻井液存在易着火、安全性差的问题，而最近使用的美国3M公司的中空玻璃微珠聚磺钻井液又存在固控困难、钻井液费用很高等难题。为此，从选择合适的润湿反转剂和阻燃剂入手，在室内对获得的超低密度硬胶极压型油包水乳化钻井液成果配方进行了全面评价，并应用在广安002 H9井水平段欠平衡钻井中取得了良好效果。室内研究与现场应用表明，超低密度硬胶极压型油包水乳化钻井液能够很好地满足广安构造水平井段欠平衡钻井的需要。该钻井液体系具有防塌、润滑、携砂能力强，密度容易控制，钻井液单位成本合理并可重复使用，安全性好等显著特点，适合在类似广安构造的水平井段中推广应用。     

Influence of CYP3A5 polymorphism on tacrolimus blood concentrations in renal transplant patients

Objective Tacrolimus is an immunosuppressive drug with narrow therapeutic range and wide interindividual variation in its pharmacokinetics. Tacrolimus is a substrate of cytochrome P450(CYP)3A5. The aim of this study was to evaluate whether the A6986G polymorphism is associated with tacrolimus concentration /dose ratio. Methods Fifty-two Chinese renal transplant patients were enrolled in this study. Their body weight, dosage and concentration of tacrolimus were observed. CYP3A5 genotype was determined by polymerase chain reaction followed by restriction fragment length polymorphism analysis. Results A significant association was found between tacrolimus levels per dose/kg/d and CYP3A5 gene A6986G polymorphism (P<0.001). The CYP3A5 * 3 * 3 patients have a significantly higher tacrolimus level/dose than CYP3A5 * 1 * 1 and CYP3A5 * 1 * 3. Conclusions CYP3A5 gene A6986G polymorphism is associated with tacrolimus pharmacokinetics and dose requirements. Pharmacogenetic methods could be employed prospectively to help the dose selection and to individualize immunosuppressive therapy according to the result. Foundation item: Project (03GZ3072) supported by the Science and Technology Department of Hunan Province; project (2004035206) supported by the China Postdoctoral Foundation and project (30300383) supported by the National Natural Sciences Foundation of China     

On effective offloading services for resource-constrained mobile devices running heavier mobile internet applications

Rapid advances in wireless mobile network technologies and mobile handsets (MHs) facilitate ubiquitous infrastructure that can support a range of mobile services and applications in addition to conventional mobile Internet access. One recent trend is to effectively run desktop PC-oriented heavier applications on MHs. However, due to their miniature, portable size, MHs are resource-constrained and therefore, running these applications directly on an MH is not satisfactory given a user's expectations. To cope with this problem, this article proposes a novel offloading service that can seamlessly offload some of the tasks of a mobile application from an MH to nearby, resource-rich PCs (called surrogates). The system architecture and key components of the proposed offloading service are presented, prototyped, and evaluated. The results of experiments and simulations have demonstrated the effectiveness and efficiency of this offloading service for mobile applications.     

湖南省水库与城市水资源供求评价

对湖南省29个城市及靠近这些城市的67座大中型水库,采用模糊数学多级多因子综合评价方法,按水库人均供水量、水质类别、水库向城市可供水率等8个评价指标及其隶属度,评价得到2020年湖南省水库向城市可供水资源的程度.分析结果表明:至2020年,近城水库供水资源完全满足城市需水量的有7个城市,基本满足需水的城市有10座,说明在当前与将来城市供水资源紧缺的形势下,开发现有水库水资源,向城市供水意义重大.     

嵌入式Web服务器在中小水电信息采集系统中的应用

中小水电站大多数建在偏远山区，并网管理难度非常大，解决中小水电站的信息传输是主要的技术难点之一。随着计算机技术的发展，嵌入式Web服务器技术在远程监控和实时通信系统中的应用越来越广泛。将Web技术引入中小水电站信息采集系统中，可以实现对中小水电站基于浏览器方式的远程监控。文中结合中小水电站通信结构，介绍了嵌入式Web服务器技术在中小水电站信息采集系统中的应用。     

A Study on NMR and GC/MS Spectra of the Isomers of Linear Hexyl Naphthalene

The GC/MS and NMR analysis of the reaction products of naphthalene with 1-bromohexane were reported. The products obtained were suggested to have six isomers of linear hexylnaphthalene and the structure of each isomer was determined by GC/MS and NMR spectra. For the first time, the unique chemical shift data were obtained. The content of each isomer calculated by ¹H NMR and ¹³C NMR spectra was consistent with that by GC/MS spectra, which confirmed the accuracy of NMR data.     

Oxides Catalysts of Rare Earth and Transient Metal for Catalytic Oxidation of Benzene

The catalysts of CeO2 and the mixture of CeO2 and CuO were prepared, and the activities of these catalysts for completely oxidizing benzene were studied.The results show that the optimal proportion of CeO2/CuO is 6: 4.The highest temperature at which benzene was completely oxidized on these catalysts at different airspeed was measured.Compared these catalysts with the noble metal used, our catalysts had superiority in the resources and the industrial cost besides good activities.     

复合布尔函数中含某单乘积项的快速判定算法

引入了布尔函数的基本积、单乘积项等概念，通过实例剖析了复合布尔函数中是否含某一单乘积项的一般判定方法，在该基础上提出了一种快速判定途径，并给出了快速判定算法的具体描述，同时对算法进行了实验，结果表明该算法快速有效。     

非透视3点问题的解析解

由于在机器人导航等领域新的图像装置不符合透视规则,无法运用传统的透视位置估计方法,采用吴氏零点分解方法,给出非透视3点问题的解析解.利用新图像装置的几何条件,建立了非透视3点方程系统.