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91.
茯砖茶发酵、干燥过程中,烘房内温湿度稳定性和能源系统低能耗是保证茯砖茶品质与成本的重要因素。本文采用TRNSYS仿真与实验研究相结合的方法,对咸阳某茯砖茶厂实际使用的空气源热泵系统进行建模,通过研究各季节典型代表月烘房温湿度的波动情况,确定该空气源热泵系统在全年的运行状态是否满足工艺要求,在此基础上,对比了该系统在全年可运行季节代表月与该生产厂房早期使用的燃气锅炉系统的能耗仿真结果,对空气源热泵系统的节能与环保特性进行研究。结果表明:由于夏季送风质量流量过大且室外空气含湿量较高,7月烘房温湿度不满足工艺要求。热泵系统在1、4、10月的总标煤消耗量的平均值是锅炉系统的44.42%,平均CO2、SO2、NOx排放量分别为锅炉系统的34.13%、44.1%、40.60%。在茯砖茶发酵、干燥的过程中,相比于燃气锅炉系统,空气源热泵系统具有更好的节能与环保特性。 相似文献
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Cho-Yi Chen Masaoki Kawasumi Tien-Yun Lan Chi-Lam Poon Yi-Sian Lin Pin-Jou Wu Yao-Chung Chen Bing-Hong Chen Cheng-Hsien Wu Jeng-Fan Lo Rueyhung Roc Weng Yi-Chen Sun Kai-Feng Hung 《International journal of molecular sciences》2021,22(1)
Endoplasmic reticulum (ER) stress response is an adaptive program to cope with cellular stress that disturbs the function and homeostasis of ER, which commonly occurs during cancer progression to late stage. Late-stage cancers, mostly requiring chemotherapy, often develop treatment resistance. Chemoresistance has been linked to ER stress response; however, most of the evidence has come from studies that correlate the expression of stress markers with poor prognosis or demonstrate proapoptosis by the knockdown of stress-responsive genes. Since ER stress in cancers usually persists and is essentially not induced by genetic manipulations, we used low doses of ER stress inducers at levels that allowed cell adaptation to occur in order to investigate the effect of stress response on chemoresistance. We found that prolonged tolerable ER stress promotes mesenchymal–epithelial transition, slows cell-cycle progression, and delays the S-phase exit. Consequently, cisplatin-induced apoptosis was significantly decreased in stress-adapted cells, implying their acquisition of cisplatin resistance. Molecularly, we found that proliferating cell nuclear antigen (PCNA) ubiquitination and the expression of polymerase η, the main polymerase responsible for translesion synthesis across cisplatin-DNA damage, were up-regulated in ER stress-adaptive cells, and their enhanced cisplatin resistance was abrogated by the knockout of polymerase η. We also found that a fraction of p53 in stress-adapted cells was translocated to the nucleus, and that these cells exhibited a significant decline in the level of cisplatin-DNA damage. Consistently, we showed that the nuclear p53 coincided with strong positivity of glucose-related protein 78 (GRP78) on immunostaining of clinical biopsies, and the cisplatin-based chemotherapy was less effective for patients with high levels of ER stress. Taken together, this study uncovers that adaptation to ER stress enhances DNA repair and damage tolerance, with which stressed cells gain resistance to chemotherapeutics. 相似文献
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Wenlong Song Shoujun Wang Yang Lu Xuan Zhang Zixiang Xia Kai Sun Guangming Xin 《Ceramics International》2021,47(9):12631-12640
To enhance the tribological performance of Si3N4/TiC ceramics, MoS2/PTFE composite coatings were deposited on the ceramic substrate through spraying method. The micrographs and basic properties of the MoS2/PTFE coated samples were investigated. Dry sliding friction experiments against WC/Co ball were performed with the coated ceramics and traditional ones. These results showed that the composite coatings could significantly reduce the friction coefficient of ceramics, and protect the substrate from adhesion wear. The primary tribological mechanisms of the coated ceramics were abrasive wear, coating spalling and delamination, and the tribological property was transited from slight wear to serious wear with the increase of load because of the lower surface hardness and shear strength. The possible mechanisms for the effects of MoS2/PTFE composite coatings on the friction performance of ceramics were discussed. 相似文献
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针对某金矿,在回收金银的基础上,对金银浮选尾矿进行云母和长石浮选,以及提纯石英试验,最终获得SiO2品位99.91%的石英产品。提纯石英产品与比利时矽比科矿业有限公司石英产品进行对比试验,通过化学成分、粒度组成、熔制、粘度和热膨胀系数测试对比试验,得出金矿提纯石英达到甚至超过矽比科进口石英产品的各项技术指标。 相似文献
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The exploitation of recycled carbonaceous catalysts from renewable biomass resources such as chitin is a crucial issue for the development of the sustainable society. In this article, the chitin-based N and O doped carbon microspheres (ChC) were fabricated by a simple dissolution, sol–gel transformation, and the carbonization methods. Subsequently, the novel magnetic Ag-Fe3O4@chitin-based carbon microspheres catalyst (MChC) was successfully constructed through the in situ redox reaction. The as-prepared MChC possessed rich micropores with high-surface area, and a narrow size distribution (50–120 μm). The Ag-Fe3O4 nanoparticles were immobilized through the interaction with C, N, and O atoms in the pores of MChC. The reduction of 4-nitrophenol was applied to evaluate the catalytic activity of MChC. 4-Nitrophenol (4-NP) could be fully reduced to 4-aminophenol (4-AP) in 5 min with the catalyst MChC-45. Moreover, MChC could be collected in solution with an external magnet in 8 s and remained relatively high-catalytic activity after 10 cycle times. This work provided novel ideas for the fabrication of doped carbon material from biomass and promoted its utilization in nanocatalytic applications. 相似文献