Thiamine concentrations in lake whitefish eggs from the upper Great Lakes are related to maternal diet

Thiamine deficiency is responsible for reproductive impairment in several species of salmonines in the Great lakes, and is thought to be caused by the consumption of prey containing thiaminase, a thiamine-degrading enzyme. Because thiaminase levels are extremely high in dreissenid mussels, fish that prey on them may be susceptible to thiamine deficiency. We determined thiamine concentrations in lake whitefish Coregonus clupeaformis eggs from the upper Laurentian Great Lakes to assess the potential for thiamine deficiency and to determine if thiamine concentrations in lake whitefish eggs were related to maternal diet. Mean thiamine concentrations in lake whitefish eggs were highest in Lake Huron, intermediate in Lake Superior, and lowest in Lake Michigan. Some fish had thiamine concentrations below putative thresholds for lethal and sublethal effects in salmonines, suggesting that some larval lake whitefish may currently be at risk of at least sublethal effects of low thiamine concentrations, although thiamine thresholds are unknown for lake whitefish. Egg thiamine concentrations in lake whitefish eggs were statistically significantly related to isotopic carbon signatures, suggesting that egg thiamine levels were related to maternal diet, but low egg thiamine concentrations did not appear to be associated with a diet of dreissenids. Egg thiamine concentrations were not statistically significantly related to multifunction oxidase induction, suggesting that lower egg thiamine concentrations in lake whitefish were not related to contaminant exposure.     

A wireless embedded tongue tactile biofeedback system for balance control

We describe the architecture of an original biofeedback system for balance improvement for fall prevention and present results of a feasibility study. The underlying principle of this biofeedback consists of providing supplementary information related to foot sole pressure distribution through a wireless embedded tongue-placed tactile output device.Twelve young healthy adults voluntarily participated in this experiment. They were asked to stand as immobile as possible with their eyes closed in two conditions of no-biofeedback and biofeedback. Centre of foot pressure (CoP) displacements were recorded using a force platform. Results showed reduced CoP displacements in the biofeedback relative to the no-biofeedback condition.On the whole, the present findings evidence the effectiveness of this system in improving postural control on young healthy adults. Further investigations are needed to strengthen the potential clinical value of this device.     

Disturbance attenuation by dynamic output feedback for input-delay systems

This paper addresses the optimal disturbance attenuation problem by output feedback for multivariable linear systems with delayed inputs. The attenuation is optimal in the sense that the controller minimizes the maximal amplitude of the plant output in response to such a disturbance. The controller is a general feedback, involving an observer, a state predictor, and a predicted state feedback. The optimal disturbance attenuation problem is formulated in terms of an equivalent system without delay. The optimal bound of the disturbance attenuation is then characterized, and it is shown that the optimal controller tends to have high gains. A necessary and sufficient condition to guarantee the existence of an optimal solution is provided using the geometric approach.     

Use of a laser beam with an oblique angle of incidence to measure the reduced scattering coefficient of a turbid medium

A simple and quick approach is used to measure the reduced scattering coefficient (μ(s)') of a semi-infinite turbid medium having a much smaller absorption coefficient than μ(s)'. A laser beam with an oblique angle of incidence to the medium causes the center of the diffuse reflectance that is several transport mean-free paths away from the incident point to shift away from the point of incidence by an amount Δx. This amount is used to compute μ(s)' by μ(s)' = sin(α(i))/(nΔx) where n is the refractive index of the turbid medium divided by that of the incident medium and α(i) is the angle of incidence measured from the surface normal. For a turbid medium having an absorption coefficient comparable with μ(s)', a revision to the above formula is made. This method is tested theoretically by Monte Carlo simulations and experimentally by a video reflectometer.     

Analytic investigation of frequency sensitivity in microwave oscillators: Application to the computation of phase noise in a dielectric resonator oscillator

The conversion of low frequency noise into phase noise in microwave oscillators is studied through an analytical calculation of the pushing factor. This calculation is based on a simplified equivalent circuit for two types of active devices : field effect transistors (Fet) and heterojunction bipolar transistors (hbt). The preeminence in the conversion process of the gate- source capacitance in theFet and the base- emitter junction in thehbt is pointed out. Practical methods are proposed to reduce the phase noise in these circuits.     

Computations on one-dimensional cellular automata

Cellular automata may be viewed as a modelization of synchronous parallel computation. Even in the one-dimensional case, they are known as capable of universal computations. The usual proof uses a simulation of a universal Turing machine. In this paper, we present how a one-dimensional cellular automata can simulate any recursive function in such a way that composition of computations occurs as soon as possible. In addition, this allows us to show that one-dimensional cellular automata may simulate asynchronous computations.This work was supported by the Programme de Recherches Coordonnées Mathématiques et Informatique and the Esprit Basic Research Action Algebraic and Syntactical Methods in Computer Science.     

A semantics of introspection in a reflective prototype-based language

In Malenfant et al. [19], we have described a reflective model for a prototype-based language based on thelookup o apply reflective introspection protocol. In this paper, we augment our previous protocol by converting it to handle continuations reified as first-class objects. First-class continuations provide much more control over the current computation; during the introspection phase fired by message sending, they make it possible not only to change the behavior of the program for that message but also for the entire future computation. In this paper, we provide this introspection protocol with a formal semantics. This result is obtained by exhibiting a mapping from program configurations to priority rewrite systems (PRS) as well as a mapping from message expressions to ground first-order terms used to query the PRS. Other advantages of this approach are: to ensure the termination of the introspection using the smallest set of formally justified conditions and to provide a clear declarative account of this reflective protocol. The PRS also appears as a meta-level to the base language, independent of the implementation, but from which we derive fundamental clues to obtain an efficient language processor. By our new model, we finally highlight the link between reflection in object-oriented languages and the one originally proposed by 3-Lisp [24], although object-orientation provides reusability to reflection, making it easier to use.     

Scenario-based testing from UML/OCL behavioral models

We present in this article a way to produce test suites applied to the POSIX mini-challenge based on a behavioral model of a file system manager written in UML/OCL. We illustrate the limitations of a fully automated test generation approach, which justifies the use of test scenarios as a complement to a functional testing approach. Scenarios are expressed through regular expressions describing sequences of operations, possibly punctuated by intermediate states that have to be reached by the execution of the model. Scenarios are unfolded into extended sequences of operations that are played on the model using symbolic animation techniques. We experimented our approach by testing the conformance of two different file systems w.r.t. the POSIX standard: a recent Linux distribution and a customized Java implementation of POSIX used to evaluate the relevance of our approach and its complementarity with a structural test generation approach.     

Indexing and querying segmented web pages: the BlockWeb Model

We present in this paper a model for indexing and querying web pages, based on the hierarchical decomposition of pages into blocks. Splitting up a page into blocks has several advantages in terms of page design, indexing and querying such as (i) blocks of a page most similar to a query may be returned instead of the page as a whole (ii) the importance of a block can be taken into account, as well as (iii) the permeability of the blocks to neighbor blocks: a block b is said to be permeable to a block b?? in the same page if b?? content (text, image, etc.) can be (partially) inherited by b upon indexing. An engine implementing this model is described including: the transformation of web pages into blocks hierarchies, the definition of a dedicated language to express indexing rules and the storage of indexed blocks into an XML repository. The model is assessed on a dataset of electronic news, and a dataset drawn from web pages of the ImagEval campaign where it improves by 16% the mean average precision of the baseline.