中西医结合治疗输卵管阻塞性不孕84例

中西医结合治疗输卵管阻塞性不孕８４例新绛县计划生育服务站（０４３１００）赵秀英太原市人民医院丰桂香１９８１年１０月至１９９３年６月间，笔者采用中西医结合方法治疗输卵管阻塞性不孕８４例，疗效较为满意，现总结报道如下。一、一般资料本组８４例，年龄２２岁～...     

血浆置换模型与血浆胆红素浓度的变化规律

目的：探讨血浆置换过程中胆红素浓度随血浆置换量的变化规律，为临床大夫制定合理的血浆置换用量提供合理的理论依据。方法：通过对立血浆置换的数学模型，导出血浆置换过程中胆红素浓度与血浆置换量的解析表达式，通过对实验测量值的拟合确定模型参数。结果：通过与47例血浆置换的实验测量值比较，该模型的解析表达式较好地反映了血浆置换过程中胆红素浓度的实际变化规律。结论：胆红素浓度随血浆置换量的变化成指数衰减规律。随着血浆置换量的增加，胆红素浓度下降的速度逐渐减慢。     

体内摄人147Pm时诱发放射遗传毒理效应研究

本文研究了机体摄八不周量的¹⁴⁷Pm时诱发的骨髓细胞染色体畸变、姐妹染色单体互换(SCE)频率和微核率的变化过程.实验结果发现¹⁴⁷Pm嚣发的骨髓细胞染色体畸变以染色单体型蹄变为主,且随着¹⁴⁷Pm撮入量的增加,染邑体琦变也相应增多,并可出现染色体断片和易位．研究表明,骨髓细胞染色体畸变率与¹⁴⁷Pm摄人量之同呈半对致直线效应关系,拟合的半对数回归方程式为:Y=-4．403+1．435LnX．同时电观察到骨髓畸变细胞与¹⁴⁷Pm的摄八量之间亦呈线性关系．¹⁴⁷Pm内污染后．诱发骨髓细胞SCE须率和徽核阳性率明显升高.且随着¹⁴⁷Pm摄入量的增加微核率也有所增加.     

除烦汤治疗情志病疗效观察

除烦汤治疗情志病疗效观察赵秀英首都医科大学附属天坛医院（１０００５０）１临床资料１．１一般资料本组７０例，男４例，女６６例；年龄１９～６８岁，其中３０～５０岁者占７８．５５％；病程２周～１２ａ，以２～５ａ者居多。本组诊为神经官能症１４例，精神分裂症８...     

复方牛胎肝提取物减轻非酒精性脂肪性肝炎大鼠肝脏脂肪变性及炎症程度

非酒精性脂肪性肝病(NAFLD)包括单纯性脂肪肝、脂肪性肝炎(NASH)和肝硬化,NASH是NAFLD进展的关键过程;目前尚无满意治疗药物[1].复方牛胎肝提取物主要成分为胰岛素样生长因子([GF)-I、肝细胞生长因子(HGF)等.     

卡维地洛治疗慢性心力衰竭40例疗效观察

目的评估卡维地洛治疗慢性心力衰竭的临床疗效及安全性。方法80例慢性心力衰竭患者随机分为治疗组和对照组各40例。对照组采用慢性心力衰竭的标准治疗;治疗组在此标准治疗的基础上,卡维地洛从小剂量2．5mg／次、2次／d开始,每2周增加1倍剂量,直至最大剂量（靶剂量）25mg,2次／d。治疗前后分别对两组患者行血常规、心电图、心功能、肝肾功能、心脏B超等检查。结果治疗6个月后,治疗组左室收缩末径、左室舒张末径减小,左室射血分数增加,且血压、心率均明显改善,与治疗前比较差异有统计学意义（P〈0．05或〈0．01）;而对照组治疗前后以上指标比较差异无统计学意义。两组治疗后肝肾功能、血常规均无异常改变。结论卡维地洛治疗慢性心力衰竭安全、有效。     

获得性免疫缺陷综合征患者胃黏膜组织人类免疫缺陷病毒感染分析

Objective To investigate the distribution and amount of human immunodeficiency virus (HIV) infection in gastric mucosa from untreated acquired immune deficiency syndrome (AIDS) patients and highly active antiretroviral therapy (HAART) treated patients.Methods Thirty-five AIDS patients (14 untreated patients and 21 patients receiving HAART) and 10 HIV-1 seronegative patients with gastrointestinal symptoms were enrolled and examined by upper endoscopy.The labeled HIV-1 double-stranded cDNA probe was a PCR product corresponding to the LTR and gag gene of the HIV-1 genome.HIV in gastric mucosal tissues from AIDS patients was detected using in situ hybridization (ISH) and compared with that in peripheral blood mononuclear cells (PBMC).Results ① No obvious character was found in gastrointestinal symptoms,endoscopy examination and pathology results of AIDS patients.② The expression of HIV gene was mainly detected in the gastric mucosal mononuclear cell (MMC).Other cells were also observed with HIV expression including mucosal epithelial cells,gland epithelial cells and interstitial cells.③There was no difference in HIV expression between sinus ventriculi and gastric body.④ HIV gene expression from AIDS patients was (1.97±3.25)% in gastric mucosa,no difference in HIV gene expression between two groups (P＞0.05).⑤ HIV gene expression in PBMC smear from AIDS patients was (12.38 ± 9.17)%.HIV expreesion in PBMC from patients who had received HAART for 1-4 years were markedly lower than that from patients who had not received HAART (P＜0.05).Conclusions The gastric mueosa is one of HIV infected sites.The potential effect of HAART on the decrease of HIV infected cells in gastric mucosa was unsatisfactory.     

学院型医院（academic hospital）建设与医院临床实验室的发展的思考

建设学院型医院是近年许多参与医学教育的临床医院提出的发展目标。高质量、有特色的重点学科能有效促进医疗、教学、科研工作整体发展。临床实验室应根据工作特点,顺应形势,调整在学院型医院建设中的发展思路,找到一条适合自己的发展模式。     

步长稳心颗粒治疗室性早搏临床观察

室性早搏是临床常见的心律失常,目前抗心律失常药物存在一定的副作用,近年来,我们用步长稳心颗粒治疗频发室性早搏,疗效满意。1资料与方法1.1研究对象1.1.1入选标准选择符合以下条件的不同病因的门诊或住院的室性早搏患者120例：①器质性心脏病和非器质性心脏病的单形、多源、多形,成对室性早搏,早搏次数〉30次/h,伴心悸、气短、乏力、失眠等症状。