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61.
Bas C. Stunnenberg MD Samantha LoRusso MD W. David Arnold MD Richard J. Barohn MD Stephen C. Cannon MD PhD Bertrand Fontaine MD PhD Robert C. Griggs MD Michael G. Hanna FRCP FMedSci Emma Matthews MRCP PhD Giovanni Meola MD PhD Valeria A. Sansone MD PhD Jaya R. Trivedi MD Baziel G.M. van Engelen MD PhD Savine Vicart MD Jeffrey M. Statland MD 《Muscle & nerve》2020,62(4):430-444
The nondystrophic myotonias are rare muscle hyperexcitability disorders caused by gain-of-function mutations in the SCN4A gene or loss-of-function mutations in the CLCN1 gene. Clinically, they are characterized by myotonia, defined as delayed muscle relaxation after voluntary contraction, which leads to symptoms of muscle stiffness, pain, fatigue, and weakness. Diagnosis is based on history and examination findings, the presence of electrical myotonia on electromyography, and genetic confirmation. In the absence of genetic confirmation, the diagnosis is supported by detailed electrophysiological testing, exclusion of other related disorders, and analysis of a variant of uncertain significance if present. Symptomatic treatment with a sodium channel blocker, such as mexiletine, is usually the first step in management, as well as educating patients about potential anesthetic complications. 相似文献
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Peter Luke BSc MSc Ewen Shepherd MBChB FRCP Tim Irvine MBChB FRCP Rae Duncan MBChB MSc MRCP 《Echocardiography (Mount Kisco, N.Y.)》2020,37(12):2163-2167
Inadvertent endocardial lead malposition is recognized as a rare incident which is usually underreported and if recognized during implantation can be easily corrected. This phenomenon is caused by the ventricular lead unintentionally crossing a pre-existing patent foremen ovale, septal defects (atrial or ventricular) or directly from the aorta via an accidental subclavian puncture resulting in the lead implanting into the left ventricle. While this is a rare occurrence we report, the incidental finding of pacemaker lead malposition during a routine follow-up transthoracic echocardiogram and the benefits of three-dimensional transesophageal echocardiography in this patient prior to lead extraction. 相似文献
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Katrice M. Karanfilian MD Monica N. Valentin MD Rajendra Kapila MD Chinmoy Bhate MD Mahnaz Fatahzadeh DMD MSD FRCP Edin Giuseppe Micali MD FRCP Edin Robert A. Schwartz MD MPH DSc FRCP 《International journal of dermatology》2020,59(10):1185-1190
Cervicofacial actinomycosis is an uncommon, chronic, suppurative, and granulomatous bacterial infection. It is often of dental origin and tends to mimic other dental infections, granulomatous disorders, and cancers. The initial diagnostic workup, predicated upon imaging and tissue biopsies, is frequently nonspecific. A definitive diagnosis is usually rendered only after surgical excision and histologic examination of the cervicofacial mass. We propose a classification of three stages: localized infection without sinus involvement, localized infection with sinus involvement, and disseminated infection, to facilitate recognition, diagnosis, and early aggressive treatment. Untreated infection may be life-threatening. Therapy may require long-term antibiotics; however, many cases may also necessitate complete surgical excision. 相似文献
64.
Caroline Bleakley MD MRCP Mark Monaghan PhD FRCP FACC FESC 《Echocardiography (Mount Kisco, N.Y.)》2020,37(10):1654-1664
Recently, there has been an increasingly minimalistic approach to transcatheter aortic valve replacement (TAVR), with most procedures now performed under conscious sedation without real time transesophageal echocardiography (TEE) guidance. Proponents of echo should not feel discouraged by this; it is the initial insights that were gained with procedural TEE during the early years of TAVR that have allowed the procedure's gradual maturation and sophistication. Experienced centers that have promoted extensive TAVR TEE programs continue to maximize the benefits of echocardiography in both procedural planning and execution. Critical to this is the understanding of 3D TEE, allowing the annulus to be sized accurately, relevant neighboring anatomy defined, and complications flagged. This review will outline the current application of 3D TEE in TAVR and discuss challenges and opportunities for 3D echocardiography in this field. 相似文献
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Joanne Ng MD PhD Elisenda Cortès-Saladelafont MD Lucia Abela MD Pichet Termsarasab MD Kshitij Mankad FRCR Sniya Sudhakar FRCR Kathleen M. Gorman MD Simon J.R. Heales PhD Simon Pope PhD Lorenzo Biassoni MSc FRCP FEBNM Barbara Csányi MD John Cain FRCR PhD Karl Rakshi MBChB Helen Coutts MD Sandeep Jayawant MD FRCPCH Rosalind Jefferson MBBS PhD Deborah Hughes MSc Àngels García-Cazorla MD PhD Detelina Grozeva PhD F. Lucy Raymond MD PhD Belén Pérez-Dueñas MD PhD Christian De Goede MD Toni S. Pearson MD Esther Meyer PhD Manju A. Kurian MD PhD 《Movement disorders》2020,35(8):1357-1368
68.
Hospital care following emergency admission: a critical incident case study of the experiences of patients with advanced lung cancer and Chronic Obstructive Pulmonary Disease 下载免费PDF全文
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Appropriateness,diagnostic value,and outcomes of repeat testing following index echocardiography 下载免费PDF全文
Alina Hua MBBS Vincent McCaughan MBBS Matthew Wright MBBS Abbas Zaidi MBBS MD Jessica Wright MBBS Aishah Azam MBBS Sujata Bhattacharyya MBBS Lisanne Stock MBBS Guy Lloyd MD FRCP Sanjeev Bhattacharyya MD MRCP FESC 《Echocardiography (Mount Kisco, N.Y.)》2018,35(1):24-29