全文获取类型
收费全文 | 1416篇 |
免费 | 67篇 |
国内免费 | 11篇 |
学科分类
工业技术 | 1494篇 |
出版年
2024年 | 5篇 |
2023年 | 25篇 |
2022年 | 75篇 |
2021年 | 71篇 |
2020年 | 71篇 |
2019年 | 46篇 |
2018年 | 89篇 |
2017年 | 68篇 |
2016年 | 46篇 |
2015年 | 39篇 |
2014年 | 81篇 |
2013年 | 138篇 |
2012年 | 76篇 |
2011年 | 105篇 |
2010年 | 71篇 |
2009年 | 79篇 |
2008年 | 73篇 |
2007年 | 59篇 |
2006年 | 42篇 |
2005年 | 50篇 |
2004年 | 39篇 |
2003年 | 15篇 |
2002年 | 26篇 |
2001年 | 19篇 |
2000年 | 10篇 |
1999年 | 7篇 |
1998年 | 12篇 |
1997年 | 11篇 |
1996年 | 4篇 |
1995年 | 8篇 |
1994年 | 10篇 |
1993年 | 1篇 |
1992年 | 6篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1987年 | 3篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1981年 | 3篇 |
1979年 | 2篇 |
1978年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有1494条查询结果,搜索用时 31 毫秒
61.
Rajesh Krishna Ann Horowitz Patrick Larson James Bolognese Eugene E. Marcantonio 《Drug development and industrial pharmacy》2017,43(7):1173-1177
Objectives: A new improved mometasone furoate (Elocon?) cream with an emulsification system that produces a stable emulsion has been developed. In order to register the product in various markets, it was essential to ensure the cream was topically well tolerated and that it was bioequivalent to the reference product.Methods: Phase I clinical studies were performed to assess the local safety and tolerability upon multiple dosing of this new cream as well as to assess the single-dose bioequivalence relative to the marketed product. Bioequivalence was assessed using a vasoconstrictive assay (VCA) after a dose-duration pilot study was completed with the marketed Elocon cream.Key findings: The new mometasone cream and its vehicle were nonirritating in healthy subjects during 21-day patch application (MCII <0.025). The positive control was moderately irritating in the same study. The pivotal VCA study enrolled 162 subjects with 105 detectors included in the analysis of bioequivalence. In the 105 detectors, the ratio (×100%) of AUEC values at ED50 for test vs. standard (90% CI) was 112.91% (105.55, 120.87), within the bioequivalence criteria of (80, 125).Conclusions: These studies supported the registration of reformulated mometasone cream in various markets. 相似文献
62.
Lakshmy Rajesh Amina Al-Farsi 《The International journal of environmental studies》2017,74(6):979-990
The paper reports the first study of diversity and distribution of freshwater macrophytes in the wedian (plural of wadi = seasonal river) of the northern Al Hajar Mountain range in Oman. Fifteen lentic habitats in the wedian were surveyed. The number of species, their growth forms and abundance were recorded in the studied habitat of each wadi. In all, 41 species belonging to 14 families and 32 genera were collected. Of these 37 species were emergent and four were submergent. Poaceae was the most diverse emergent family with 17 species. Phragmites australis was the most common emergent followed by Typha domingensis. Among submerged macrophytes, Chara vulgaris had higher frequency of occurrence with low abundance followed by Potamogeton distinctus with relatively high abundance. Floristic diversity was estimated using species richness (Margalef’s D), general diversity (Shannon–Wiener H′), evenness (Pielous’s EH), and dominance (Berger–Parker d) indices for each study habitat. Principal component analysis was used to evaluate the variability using four indices. PC1 and PC2 explained 98.18% of the variability. Some habitats in different watersheds exhibited similar species diversity, but some in the same watershed were different. Baseline data on the freshwater macrophytes in northern Oman are provided here. 相似文献
63.
Optimal oxygen enrichment conditions for sponge iron rotary kiln have been successfully explored on an industrial scale using a data-driven model. A multi-objective optimisation by genetic algorithm (MOGA) is employed to find the favourable conditions. The objective function for MOGA is derived from neural networks using pre-processed operational data. From industrial experimentations guided by the optimum conditions predicted by the present model, it emerged that when the coal fines injection is maintained at 1.75?tph and the oxygen enrichment is 8 Nm3?t?1 of sponge iron, a reduction in the specific air requirement from 2609 to 2150?Nm3?t?1 was obtained, while the end-zone bed temperature remained under control at 1132°C. These conditions resulted in a reduction of specific coal consumption by 6%, an enhancement in the sponge iron production by 6% and an increase in the rotary kiln campaign life from 50 to 100 days. 相似文献
64.
In wireless communications, both control information and payload (user-data) are concurrently transmitted and required to be successfully recovered. This paper focuses on block-level detection, which is applicable for detecting transmitted control information, particularly when this information is selected or chosen from a finite set of information that are known at both transmitting and receiving devices. Using an orthogonal frequency division multiplexing architecture, this paper investigates and evaluates the performance of a time-domain decision criterion in comparison with a form of Maximum Likelihood (ML) estimation method. Unlike the ML method, the proposed time-domain detection technique requires no channel estimation as it uses the correlation (in the time-domain) that exists between the received and the transmitted selective information as a means of detection. In comparison with the ML method, results show that the proposed method offers improved detection performance, particularly when the control information consists of at least 16. However, the implementation of the proposed method requires a slightly increased number of mathematical computations. 相似文献
65.
Milk proteins are susceptible to chemical changes during processing and storage. We used proteomic tools to analyse bovine αS1-casein in UHT milk. 2-D gels of freshly processed milk αS1-casein was presented as five or more spots due to genetic polymorphism and variable phosphorylation. MS analysis after phosphopeptide enrichment allowed discrimination between phosphorylation states and genetic variants. We identified a new alternatively-spliced isoform with a deletion of exon 17, producing a new C-terminal sequence, K164SQVNSEGLHSYGL177, with a novel phosphorylation site at S174. Storage of UHT milk at elevated temperatures produced additional, more acidic αS1-casein spots on the gels and decreased the resolution of minor forms. MS analysis indicated that non-enzymatic deamidation and loss of the N-terminal dipeptide were the major contributors to the changing spot pattern. These results highlight the important role of storage temperature in the stability of milk proteins and the utility of proteomic techniques for analysis of proteins in food. 相似文献
66.
Rajesh K. Gangwar Vinayak A. Dhumale Dimple Kumari Umesh T. Nakate S.W. Gosavi Rishi B. Sharma S.N. Kale Suwarna Datar 《Materials science & engineering. C, Materials for biological applications》2012,32(8):2659-2663
Curcumin, a natural polyphenolic compound, has astounding therapeutic applications but lacks in bioavailability mainly due to its poor solubility in water. Polyvinyl pyrrolidone (PVP) which is a proven drug carrier has been used to facilitate the conjugation of curcumin with gold nanoparticles and to improve the solubility of curcumin in water. In this conjugate diaryl heptanoid chromophore group of curcumin which is a much needed group in biomedical applications remains intact as observed from FTIR and UV–vis spectroscopy analysis. The work shows good promise for such conjugates as therapeutic-cum-imaging materials in biomedical field. 相似文献
67.
Wireless Personal Communications - Nowadays, Wireless Sensor Networks (WSNs) is enhancing for different applications. Simultaneously, energy consumption for processing the tasks in most of the... 相似文献
68.
69.
Devinder Priyadarshi Rajesh Kumar Sharma 《Journal of Mechanical Science and Technology》2016,30(3):1095-1101
Aluminium matrix composites (AMCs) now hold a significant share of raw materials in many applications. It is of prime importance to study the machinability of such composites so as to enhance their applicability. Sufficient work has been done for studying the machining of AMCs with particle reinforcements of micron range. This paper presents the study of AMCs with particle reinforcement of under micron range i.e. nanoparticles. This paper brings out the results of an experimental investigation of type and weight percent of nanoparticles on the tangential cutting force during turning operation. SiC, Gr and SiC-Gr (in equal proportions) were used with Al-6061 alloy as the matrix phase. The results indicate that composites with SiC require greater cutting force followed by hybrid and then Gr. Increase in the weight percent also significantly affected the magnitude of cutting force. RSM was used first to design and analyze the experiments and then to optimize the turning process and obtain optimal conditions of weight and type of reinforcements for turning operation. 相似文献
70.
Bhupendra Singh Nitika Devi Lakshya Mathur Rajesh K. Singh Aman Bhardwaj Sun-Ju Song Dirk Henkensmeier 《Ceramics International》2018,44(6):6170-6175
In the present work, we report a method of fabrication of dense 10 mol% Mg2+-doped cerium pyrophosphate-phosphate (Ce0.9Mg0.1P2O7-PmOn; CMP-P) composites by microwave heat-treatment of the preformed Ce0.9Mg0.1P2O7 substrates in the presence of phosphoric acid. The composite was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The microwave heating at 375 °C for 5 min resulted in the formation of dense CMP-P composites which retained most of the pyrophosphate phase. The electrical conductivity was extracted from the EIS data and for the CMP-P composite prepared by H3PO4 loading for 10 h and microwave heat-treatment for 5 min it was found to be >10?2 S m?1 in 100–250 °C range with a maximum of 0.062 S cm?1 at 190 °C, which was significant for its application as electrolyte in intermediate temperature fuel cells. 相似文献