Process Mining Approach of a New Water Quality Index for Long-Term Assessment under Uncertainty Using Consensus-Based Fuzzy Decision Support System

One of the biggest challenges in water quality monitoring is how to optimize big Data gathered from a wide range of resources. This paper presented a new software-based pathway of process mining approach for extending a flexible WQI (Water Quality Index) that would deal with uncertainties derived from missing data occurrence in short- and long-term assessments. The methodology is based on integration of four multi-criteria group decision-making models coupled with fuzzy simulation including AHP (Analytical Hierarchy Process), fuzzy OWA (Ordered Weighting Average), TOPSIS (Technique for Order Preference by Similarity to Ideal Solution), and fuzzy TOPSIS that were used for data mining and group consensus evaluation.. Examining the methodology on groundwater resources being supplied for drinking in Shiraz, Iran showed high integrity, accuracy, and proximity-to-real interpretation of water quality. This was the first study where decision-making risks such as Decision Makers’ risk-prone or risk-aversion attitudes (optimistic degree), DMs’ power, and consensus degree of each water quality parameter have been considered in WQI research. The proposed index offered a flexible choice in defining the intended project duration, stakeholders’ judgments, types of water use and water resource, standards, as well as type and number of water quality parameters. Thus, beside sustaining the unity in structure, this methodology could be suggested as a potentially WQI for other regions. The presented methodology would help more efficient monitoring of water resources for drinking purpose with respect to water quality.

     

Preparation and characterization of poly(vinyl alcohol)/gum tragacanth/cellulose nanocomposite film

The effects of gum tragacanth obtained from two species of Astragalus Gossypinus (GT-G) and A. Parrowianus (GT-P) at two levels of 10% and 30% combined with cellulose nanofibers (CNF; 5%) on the physico-mechanical and structural properties of polyvinyl alcohol (PVA) nanocomposite film were investigated in this study. The water solubility and water vapor permeability of the films decreased with increasing the content of both gums, especially in the film containing 30% GT-P. The highest values of the tensile strength (39.3 MPa) and elongation at break (445%) belonged to the treatment containing 10% GT-P (90/10P/0). The FTIR and DSC analyses confirmed good interactions between GT and PVA in the 90/10P/0 treatment. SEM images indicated the dense structure of this film as the optimum treatment. Although the presence of CNF in the films containing GT-G improved some properties, especially the Young modulus, it impaired all the functional properties of nanocomposite GT-P film.     

Comparative evaluation of performance measures for human driving skills

In this paper, we evaluate the adequacy of several performance measures for the evaluation of driving skills between different drivers. This work was motivated by the need for a training system that captures the driving skills of an expert driver and transfers the skills to novice drivers using a haptic-enabled driving simulator. The performance measures examined include traditional task performance measures, e.g., the mean position error, and a stochastic distance between a pair of hidden Markov models (HMMs), each of which is trained for an individual driver. The emphasis of the latter is on the differences between the stochastic somatosensory processes of human driving skills. For the evaluation, we developed a driving simulator and carried out an experiment that collected the driving data of an expert driver whose data were used as a reference for comparison and of many other subjects. The performance measures were computed from the experimental data, and they were compared to each other. We also collected the subjective judgement scores of the driver’s skills made by a highly-experienced external evaluator, and these subjective scores were compared with the objective performance measures. Analysis results showed that the HMM-based distance metric had a moderately high correlation between the subjective scores and it was also consistent with the other task performance measures, indicating the adequacy of the HMM-based metric as an objective performance measure for driving skill learning. The findings of this work can contribute to developing a driving simulator for training with an objective assessment function of driving skills.     

A review of interoperability assessment models

Interoperability is the ability of systems to provide services to and accept services from other systems, and to use the services exchanged so as to operate together in a more effective manner. The fact that interoperability can be improved means that the metrics for measuring interoperability can be defined. For the purpose of measuring the interoperability between systems, an interoperability assessment model is required. This paper deals with the existing interoperability assessment models. A compara- tive analysis among these models is provided to evaluate the similarities and differences in their philosophy and implementation. The analysis yields a set of recommendations for any party that is open to the idea of creating or improving an interoperability assessment model.     

Sound source localization using compressive sensing-based feature extraction and spatial sparsity

In this paper, we propose a source localization algorithm based on a sparse Fast Fourier Transform (FFT)-based feature extraction method and spatial sparsity. We represent the sound source positions as a sparse vector by discretely segmenting the space with a circular grid. The location vector is related to microphone measurements through a linear equation, which can be estimated at each microphone. For this linear dimensionality reduction, we have utilized a Compressive Sensing (CS) and two-level FFT-based feature extraction method which combines two sets of audio signal features and covers both short-time and long-time properties of the signal. The proposed feature extraction method leads to a sparse representation of audio signals. As a result, a significant reduction in the dimensionality of the signals is achieved. In comparison to the state-of-the-art methods, the proposed method improves the accuracy while the complexity is reduced in some cases.     

Human eye sclera detection and tracking using a modified time-adaptive self-organizing map

This paper investigates the use of time-adaptive self-organizing map (TASOM)-based active contour models (ACMs) for detecting the boundaries of the human eye sclera and tracking its movements in a sequence of images. The task begins with extracting the head boundary based on a skin-color model. Then the eye strip is located with an acceptable accuracy using a morphological method. Eye features such as the iris center or eye corners are detected through the iris edge information. TASOM-based ACM is used to extract the inner boundary of the eye. Finally, by tracking the changes in the neighborhood characteristics of the eye-boundary estimating neurons, the eyes are tracked effectively. The original TASOM algorithm is found to have some weaknesses in this application. These include formation of undesired twists in the neuron chain and holes in the boundary, lengthy chain of neurons, and low speed of the algorithm. These weaknesses are overcome by introducing a new method for finding the winning neuron, a new definition for unused neurons, and a new method of feature selection and application to the network. Experimental results show a very good performance for the proposed method in general and a better performance than that of the gradient vector field (GVF) snake-based method.     

Strategic reasoning about business models: a conceptual modeling approach

Strategic reasoning about business models is an integral part of service design. In fast moving markets, businesses must be able to recognize and respond strategically to disruptive change. They have to answer questions such as: what are the threats and opportunities in emerging technologies and innovations? How should they target customer groups? Who are their real competitors? How will competitive battles take shape? In this paper we define a strategic modeling framework to help understand and analyze the goals, intentions, roles, and the rationale behind the strategic actions in a business environment. This understanding is necessary in order to improve existing or design new services. The key component of the framework is a strategic business model ontology for representing and analyzing business models and strategies, using the i* agent and goal oriented methodology as a basis. The ontology introduces a strategy layer which reasons about alternative strategies that are realized in the operational layer. The framework is evaluated using a retroactive example of disruptive technology in the telecommunication services sector from the literature.     

Electrohydrodynamic‐Induced SERS Immunoassay for Extensive Multiplexed Biomarker Sensing

Cancer diagnosis and patient monitoring require sensitive and simultaneous measurement of multiple cancer biomarkers considering that single biomarker analysis present inadequate information on the underlying biological transformations. Thus, development of sensitive and selective assays for multiple biomarker detection might improve clinical diagnosis and expedite the treatment process. Herein, a microfluidic platform for the rapid, sensitive, and parallel detection of multiple cancer‐specific protein biomarkers from complex biological samples is presented. This approach utilizes alternating current electrohydrodynamic‐induced surface shear forces that provide exquisite control over fluid flow thereby enhancing target–sensor interactions and minimizing non‐specific binding. Further, the use of surface‐enhanced Raman scattering‐based spectral encoding with individual barcodes for different targets enables specific and simultaneous detection of captured protein biomarkers. Using this approach, the specific and sensitive detection of clinically relevant biomarkers including human epidermal growth factor receptor 2 (HER2); Mucin 1, cell surface associated (MUC1); epidermal growth factor receptor; and Mucin 16, cell surface associated (MUC16) at concentrations as low as 10 fg mL^?1 in patient serum is demonstrated. Successful target detection from patient samples further demonstrates the potential of this current approach for the clinical diagnosis, which envisages a clinical translation for a rapid and sensitive appraisal of clinical samples in cancer diagnostics.     

Biosynthesis of SeNPs by Mycobacterium bovis and their enhancing effect on the immune response against HBs antigens: an in vivo study

Conventional hepatitis B vaccine contains alum but is less effective to induce Th1 response. Selenium nanoparticles and Bacillus Calmette–Guerin were reported as immune modulators. In this study, SeNPs were extracted from Mycobacterium bovis and characterised. SeNPs were mixed with HBs‐Ag and administered to the mice to investigate he immune response pattern. With an addition of Se ions at a sub‐inhibitory concentration to the Sauton medium broth after 24 h, SeNPs were extracted from M. bovis and characterised by Fourier transform infrared spectroscopy, dynamic light scattering, atomic forcemicroscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, and thermogravimetric analysis. Furthermore, female inbred BALB/c mice were injected subcutaneously on the first, 14th, 28th day with 100 and 200 µg doses of that SeNPs supplemented with HBs‐Ag vaccine. Later, the total antibody, isotypes of Immunoglobulin G1, Interlukin 4, and interferon‐γ were measured by enzye‐linked immunosorbent assay. The size of the SeNPs was <150 nm. Level of total antibody and immunoglobulin G2a increased significantly in the group that received 200 µg/ml nano selenium extracted from M. bovis. SeNPs in dose of 200 µg coated with organic materials of M. bovis could induce an influential immune response in relation to the conventional HBs‐Ag vaccine.Inspec keywords: selenium, nanoparticles, nanofabrication, microorganisms, Fourier transform spectra, infrared spectra, light scattering, atomic force microscopy, X‐ray chemical analysis, transmission electron microscopy, thermal analysis, nanomedicineOther keywords: biosynthesis, selenium nanoparticles, Mycobacterium bovis, enhnced immune response, HBs antigens, Bacillus Calmette‐Guerin, immune modulators, biogenic SeNPs, immune response pattern, Sauton medium broth, Fourier transform infrared spectroscopy, dynamic light scattering, atomic force microscopy, energy dispersive X‐ray spectrum, transmission electron microscopy, thermogravimetric analysis, female inbred BALB/c mice, antibody, IgG1 isotype, IgG2a isotype, IL₄ isotype, interferon‐γ, enzyme‐linked immunosorbent assay, bacterium, time 24 h, time 14 day, time 28 day, Se     

Magnetic soy protein isolate–bovine serum albumin nanoparticles preparation as a carrier for inulinase immobilisation

Magnetic nanoparticles (NPs) were functionalised with soy protein isolate (SPI) and bovine serum albumin (BSA) for inulinase immobilisation. The results revealed the nanomagnetite size of about 50 nm with a polydispersity index (PDI) of 0.242. The average size of the SPI NPs prepared by using acetone was 80–90 nm (PDI, 0.277), and SPI–BSA NPs was 80–90 nm (PDI, 0.233), and their zeta potential was around −34 mV. The mean diameter of fabricated Fe₃ O₄ @SPI–BSA NPs was <120 nm (PDI, 0.187). Inulinase was covalently immobilised successfully through glutaraldehyde on Fe₃ O₄ @SPI–BSA NPs with 80% enzyme loading. Fourier transform infrared spectra, field emission scanning electron microscopy, and transmission electron microscopy images provided sufficient proof for enzyme immobilisation on the NPs. The immobilised inulinase showed maximal activity at 45°C, which was 5°C higher than the optimum temperature of the free enzyme. Also, the optimum pH of the immobilised enzyme was shifted from 6 to 5.5. Thermal stability of the enzyme was considerably increased to about 43% at 75°C, and K _m value was reduced to 25.4% after immobilisation. The half‐life of the enzyme increased about 5.13‐fold at 75°C as compared with the free form. Immobilised inulinase retained over 80% of its activity after ten cycles.Inspec keywords: magnetic particles, nanoparticles, proteins, molecular biophysics, nanofabrication, enzymes, Fourier transform spectra, infrared spectra, scanning electron microscopy, field emission ion microscopy, transmission electron microscopy, pH, biochemistry, nanobiotechnology, biomagnetism, electrokinetic effects, iron compoundsOther keywords: magnetic nanoparticles, soy protein isolate, bovine serum albumin, inulinase immobilisation, nanomagnetite, polydispersity index, SPI‐BSA NP, zeta potential, inulinase, glutaraldehyde, enzyme loading, Fourier transform infrared spectra, field emission scanning electron microscopy, transmission electron microscopy images, enzyme immobilisation, pH, size 80 nm to 90 nm, temperature 45 degC, temperature 75 degC, Fe₃ O₄