N,N′-alkylated Imidazolium-Derivatives Act as Quorum-Sensing Inhibitors Targeting the Pectobacterium atrosepticum-Induced Symptoms on Potato Tubers

Bacteria belonging to the Pectobacterium genus are the causative agents of the blackleg and soft-rot diseases that affect potato plants and tubers worldwide. In Pectobacterium, the expression of the virulence genes is controlled by quorum-sensing (QS) and N-acylhomoserine lactones (AHLs). In this work, we screened a chemical library of QS-inhibitors (QSIs) and AHL-analogs to find novel QSIs targeting the virulence of Pectobacterium. Four N,N′-bisalkylated imidazolium salts were identified as QSIs; they were active at the μM range. In potato tuber assays, two of them were able to decrease the severity of the symptoms provoked by P. atrosepticum. This work extends the range of the QSIs acting on the Pectobacterium-induced soft-rot disease.     

Selection of silt fence filter to retain suspended toxic particles

A silt fence filter was required to retain potentially toxic particles of 0.1 mm-diameter and larger that could become suspended in water decanted from contaminated dredge spoils. An experimental study was performed to select it. The experiments consisted of two parts, Part 1 tests were conducted according to an accepted engineering standard to compare four candidate geotextiles. Part 2 tests simulated expected field conditions, and were conducted to determine whether one geotextile selected from the Part 1 tests was likely to perform well. The geotextile selected for Part 2 tests retained particles of 0.1 mm and larger, and was installed as a silt fence filter in the field. The silt fence filter was removed shortly after dredging began because it clogged, primarily due to unexpected, high amounts of suspended sediment in the supernatant. The design of the support structure for the silt fence did not permit maintenance of the filter, which may have prevented its failure. The failure may also have been prevented if salt or other materials used to promote flocculation of the dredged spoils were readily available and used on the spoils. The selection procedure described may be helpful because the conditions tested for in the laboratory are likely to occur or could be induced.     

Self-help treatment for insomnia: Bibliotherapy with and without professional guidance.

Fifty-four adults with primary insomnia were randomly assigned to a self-help treatment (cognitive-behavioral bibliotherapy [BT]), BT with weekly phone consultations, or a waiting-list control (WL) group. Treated participants were mailed 6 treatment booklets at the rate of 1 booklet per week; 1/2 of them also received minimal professional guidance through a 15-min weekly phone consultation. The WL group members continued to monitor their sleep during this period. Participants in both treatment conditions improved significantly on the main outcome variables (total wake time and sleep efficiency) at posttreatment, whereas WL participants remained unchanged. The addition of weekly phone calls slightly enhanced improvements at posttreatment. However, both treatment conditions were comparable at follow-up. These results suggest that BT, with or without minimal professional guidance, is an effective approach for treating primary insomnia. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The preparation of flat H–Si(111) surfaces in 40% NH4F revisited

The reasons why ideally flat H–Si(111) surface can be prepared by NH₄F etching are investigated from correlation between AFM observations and experimental conditions used for etching. It is shown that pitting may be completely suppressed if a one side polished wafer is immersed in an oxygen free solution. An analytical electrochemical study of the (111) and rough face of the same n-Si wafer is presented to yield insight into observations.     

An experimental investigation on oil mist characterization used in MQL milling process

In this study, a method is developed to determine the oil mist characteristics for the minimal quantity lubricant process. The oil mist is characterized by the size, velocity, and volume flow rate of its particles. In each case, a specific measurement process is used: the laser diffraction granulometry method, the particle image velocimetry, and the gravimetric method. These methods are used in the case of static and simple models with different inner channels. Experimental tests have been done with the same inner channel as the existing spindle inner channel. Different output models with different inner canalizations have been tested, using these experimental processes. The main goal is to control the characteristics of output oil mist as a function of the input oil mist device parameters.     

Hydrolysis of grape monoterpenyl glycosides by Candida molischiana and Candida wickerhamii β-glucosidases

The exocellular β-glucosidases of Candida molischiana and Candida wickerhamii are able to hydrolyse geranyl, neryl, citronellyl, linalyl and α-terpinyl-β-D -glucopyranosides. The nature of the aglycone residue greatly affects the rate of hydrolysis. Glucosides with a tertiary alcohol as aglycone residue are more slowly hydrolysed than those with a primary alcohol. The β-glucosidase from C molischiana is also able to hydrolse α-L-arabinofuranosides. This results in the release of monoterpenols from a glycoside extract from grape juice.     

L'effet du niveau d'experiencing du client et de l'aidant sur l'abandon d'un processus thérapeutique.

Studied the effect of client and therapist level of experiencing, beginning with the initial stage of psychological counseling, on early termination of therapy. Human subjects: 32 male and female Canadian adults (mean age 30–32 yrs) (personality disorders, neuroses, or interpersonal problems) (clients of therapists). 19 normal male and female Canadian adults (mean age 31 yrs) (graduate students) (therapists). Clients were subdivided into 2 groups: those who had terminated therapy (early or late), and those who had not terminated therapy. Ss were interviewed. Levels of experiencing were compared for the 2 groups of clients and for therapists who had counseled these clients. Tests used: The Global Assessment Scale, Psychiatric Symptom Index (F. Ilfeld, 1976), and Experiencing Scale (P. Mathieu-Coughlan and M. Klein, 1984). (PsycINFO Database Record (c) 2010 APA, all rights reserved)