THE IMPACT OF SPATIAL VERSUS ECONOMIC MEASURES IN AN URBAN TRANSPORTATION PLAN

A multimodal model for traffic was developed by the Flemish administration. For the first time an integrated set of measures was taken into account to forecast statistics on car-traffic and the use of public transport systems during evening peak-hours. The measures can be classified in four groups: planning, infrastructure, regulation and financial. Each input is forecasted for 2010 by means of two opposite scenarios: a trend scenario and a policy (sustainable) scenario. The model was first tested for the Antwerp region on a very detailed geographical level. We sought to identify which measures had a significant influence on the results. As a result of a sensitivity analysis we conclude that even in the long run planning measures are least effective, followed by infrastructure measures that may stimulate local people to make use of public transport. Regulatory measures and especially financial measures have clearly the most significant impact on generation of passenger kilometres and modal choice during the evening rush hour.     

基于距离均衡化的自适应性动态轮廓模型

针对形变轮廓模型对初始位置敏感、易陷入局部极值以及不具备自动拓扑变换功能等问题，在讨论拓扑自适应的Snake模型的基础上，提出了基于距离均衡化的自适应性动态轮廓模型。该模型是首先通过顶点到其邻点连线的平均距离来改进内部能量项，使轮廓的运动更具稳定性，同时用轮廓自身的特性来决定轮廓的运动，使其具有较强的自适应性。然后通过膨胀力的构造和使用，使得该模型能够在较大范围内捕获图像的特征。用该方法对合成图像和真实图像进行的分割结果表明，效果较好。     

Developmental Changes in Facial Expressions of Emotions in the Strange Situation During the Second Year of Life.

Infants' expressions of discrete emotions were coded during the more stressful episodes (4 through 8) of the Strange Situation at 13 and 18 months. The data showed a significant decrease in full-face expressions (more complex configurations of movements) and a significant increase in component expressions (simpler and more constrained patterns of movements). The authors interpreted this trend as a developmental change toward more regulated and less intense emotions. Consistent with this view, the aggregate index of infants' full-face negative emotion expressions, interpreted as reflecting relatively unregulated intense emotions, correlated significantly with maternal ratings of difficult temperament. The authors discuss alternative interpretations of the findings in terms of changes in reactivity/arousability and the emerging capacity for self-regulation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evaluating the Endophenotype Model of ADHD Neuropsychological Deficit: Results for Parents and Siblings of Children With ADHD Combined and Inattentive Subtypes.

Neurogenetic models predict neuropsychological weaknesses in the relatives of children with attention-deficit/ hyperactivity disorder (ADHD). The authors examined executive and regulatory measures in 386 relatives (307 parents, 79 siblings) of children with ADHD combined type, ADHD inattentive type, and controls. Predicted deficits were seen on trailmaking (relatives of ADHD combined type only), stop-signal reaction times (relatives of girls only), and response variability (mothers only) but not on naming or output speed. Effects generally held, even with relatives' ADHD status controlled. A neuropsychologically impaired subgroup of children with ADHD had relatives with clear neuropsychological weaknesses. The authors conclude that a neurogenetic model of ADHD etiology is supportable only for a subset of executive functions and that neuropsychological heterogeneity warrants more examination in ADHD. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Links Between Sex-Typed Time Use in Middle Childhood and Gender Development in Early Adolescence.

The authors studied sex-typing in the kinds (e.g., sports, handicrafts) and social contexts (same- vs. other-sex companions) of children's free time activities, and the links between sex-typed activities and gender development over 2 years. Participants were 200 White, working- and middle-class children (103 girls, 97 boys; mean age = 10.86 years). In annual home interviews, children rated their self-esteem, gender role attitudes and sex-typed personality qualities, academic interests, and school grades. During 7 nightly phone interviews each year, children reported on their activities. Boys were more sex-typed than girls in their peer activities, and children were least sex-typed in their activities with siblings. Sex-typed activities in middle childhood predicted individual differences in gender development in early adolescence (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

An Exploration of Impact of Cognitive Elaboration on Learning in ISD Projects

Stakeholder learning has been considered crucial for effective participation and the success of information system development (ISD). However, little guidance has been offered as an operational method to facilitate learning in ISD settings. We argue that “cognitive elaboration” (CE) is a helpful strategy for developing effective learning in client–developer interactions in ISD efforts. Two types of learning are investigated: model-building (MB) and model-maintenance (MM). The current study investigated whether CE performed by stakeholders themselves in client–developer interaction led to their MB rather than MM learning. In addition, an alternative hypothesis has been explored: whether mere communication activities may induce learning. Fifty individuals in seven ongoing software development projects in four organizations were examined. For each project, two meetings in which clients and developers participated were observed. The empirical results demonstrated that stakeholders in an ISD process who have engaged in CE themselves are more likely to experience MB learning; and that mere communication does not account for MB learning. An insignificant link between CE and MM learning was found. This study deepens our understanding about IS–user interactions. Limitations of the current research and implications for future research are discussed.     

Efficient Total Chemical Synthesis of 13C=18O Isotopomers of Human Insulin for Isotope‐Edited FTIR

Isotope‐edited two‐dimensional Fourier transform infrared spectroscopy (2 D FTIR) can potentially provide a unique probe of protein structure and dynamics. However, general methods for the site‐specific incorporation of stable ¹³C=¹⁸O labels into the polypeptide backbone of the protein molecule have not yet been established. Here we describe, as a prototype for the incorporation of specific arrays of isotope labels, the total chemical synthesis—via a key ester insulin intermediate—of 97 % enriched [(1‐¹³C=¹⁸O)Phe^B24] human insulin: stable‐isotope labeled at a single backbone amide carbonyl. The amino acid sequence as well as the positions of the disulfide bonds and the correctly folded structure were unambiguously confirmed by the X‐ray crystal structure of the synthetic protein molecule. In vitro assays of the isotope labeled [(1‐¹³C=¹⁸O)Phe^B24] human insulin showed that it had full insulin receptor binding activity. Linear and 2 D IR spectra revealed a distinct red‐shifted amide I carbonyl band peak at 1595 cm^?1 resulting from the (1‐¹³C=¹⁸O)Phe^B24 backbone label. This work illustrates the utility of chemical synthesis to enable the application of advanced physical methods for the elucidation of the molecular basis of protein function.     

Digital canvas removal in paintings

The periodic structure of the underlying support of paintings on canvas can become quite prominent and disturbing in high resolution digital recordings. In this paper, we construct a new model and method for the digital removal of canvas which is considered as a noise component superimposed on the painting artwork. The high resolution of the images prohibits the efficient application of existing adaptive denoising filters. Hence, a two-step approach is proposed. First a (smoothing) Wiener filter is applied to the complete image. The second step consists of a spatially adaptive extension with low-complexity to obtain a generic digital canvas removal filter.     

Development and evaluation of an intervention to reduce rip current related beach drowning

The objective of this research was to evaluate a campaign to improve beachgoer recognition of calm-looking rip currents, known to contribute to surf drowning. Posters, postcards, and brochures conveying the message “Don’t get sucked in by the rip” were distributed in an intervention area. Beachgoers were interviewed in this and a similar control area one year before and immediately after the intervention (respective response rates: 69.9% and 82.3%), Consenting respondents were sent follow-up questionnaires after approximately 6 months and 55% responded. In the intervention area, 28.8% of post-intervention, and 57.2% of follow-up respondents, had seen our campaign. At post-intervention, intervention respondents demonstrated improvement (relative to baseline) in intentions to swim away from a calm-looking rip, ability and confidence in identifying a rip, intention never to swim at unpatrolled beaches, and responses to being caught in a rip, compared to the control respondents. Similar improvements were observed post-intervention for respondents in the intervention area who had seen our campaign (relative to those who had not), and at 6 month follow-up for intervention respondents (relative to control respondents). The relatively brief print-based campaign was effective in warning beachgoers about calm-looking rips.