全文获取类型
收费全文 | 5300篇 |
免费 | 439篇 |
国内免费 | 22篇 |
学科分类
医药卫生 | 5761篇 |
出版年
2024年 | 6篇 |
2023年 | 77篇 |
2022年 | 45篇 |
2021年 | 234篇 |
2020年 | 148篇 |
2019年 | 205篇 |
2018年 | 206篇 |
2017年 | 150篇 |
2016年 | 181篇 |
2015年 | 193篇 |
2014年 | 224篇 |
2013年 | 296篇 |
2012年 | 437篇 |
2011年 | 456篇 |
2010年 | 244篇 |
2009年 | 201篇 |
2008年 | 362篇 |
2007年 | 321篇 |
2006年 | 370篇 |
2005年 | 324篇 |
2004年 | 299篇 |
2003年 | 271篇 |
2002年 | 191篇 |
2001年 | 29篇 |
2000年 | 15篇 |
1999年 | 34篇 |
1998年 | 40篇 |
1997年 | 30篇 |
1996年 | 21篇 |
1995年 | 29篇 |
1994年 | 16篇 |
1993年 | 12篇 |
1992年 | 19篇 |
1991年 | 13篇 |
1990年 | 8篇 |
1989年 | 11篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 6篇 |
1980年 | 2篇 |
1976年 | 2篇 |
1971年 | 2篇 |
1967年 | 2篇 |
1933年 | 1篇 |
1930年 | 1篇 |
1924年 | 1篇 |
1906年 | 1篇 |
排序方式: 共有5761条查询结果,搜索用时 15 毫秒
91.
92.
José M. de la Torre Hernández Salvatore Brugaletta Joan A. Gómez Hospital José A. Baz Armando Pérez de Prado Ramón López Palop Belen Cid Tamara García Camarero Alejandro Diego Hipólito Gutiérrez José A. Fernández Diaz Juan Sanchis Fernando Alfonso Roberto Blanco Javier Botas Javier Navarro Cuartero José Moreu Francisco Bosa Antonio J. Domínguez 《Revista espa?ola de cardiología》2019,72(12):1005-1011
Background and objectivesPatients older than 75 years with ST-segment elevation myocardial infarction undergoing primary angioplasty in cardiogenic shock have high mortality. Identification of preprocedural predictors of short- and long-term mortality could be useful to guide decision-making and further interventions.MethodsWe analyzed a nationwide registry of primary angioplasty in the elderly (ESTROFA MI + 75) comprising 3576 patients. The characteristics and outcomes of the subgroup of patients in cardiogenic shock were analyzed to identify associated factors and prognostic predictors in order to derive a baseline risk prediction score for 1-year mortality. The score was validated in an independent cohort.ResultsA total of 332 patients were included. Baseline independent predictors of mortality were anterior myocardial infarction (HR 2.8, 95%CI, 1.4-6.0; P = .005), ejection fraction < 40% (HR 2.3, 95%CI, 1.14-4.50; P = .018), and time from symptom onset to angioplasty > 6 hours (HR 3.2, 95%CI, 1.6-7.5; P = .001). A score was designed that included these predictive factors (score “6-ANT-40”). Survival at 1 year was 54.5% for patients with score 0, 32.3% for score 1, 27.4% for score 2 and 17% for score 3 (P = .004, c-statistic 0.70). The score was validated in an independent cohort of 124 patients, showing 1-year survival rates of 64.5%, 40.0%, 28.9%, and 22.2%, respectively (P = .008, c-statistic 0.68).ConclusionsA preprocedural score based on 3 simple clinical variables (anterior location, ejection fraction < 40%, and delay time > 6 hours) may be used to estimate survival after primary angioplasty in elderly patients with cardiogenic shock and to guide preinterventional decision-making. 相似文献
93.
Background: Adolescent substance use (SU) remains a serious problem. Inpatient, primary care, and self-treatment models for chemical dependency (CD) yield varying degrees of success impacting the sequelae of chronic or episodic SU. Relational engagement among adolescent substance users is a long known influential factor in the development, maintenance and transformation of addictive behaviors. Objectives: Following tenets of Relational-Cultural Theory and using the Relational Health Indices for Youth (RHI-Y), a validated survey tool for adolescents, we sought to measure relational health (RH) during times of transitions during CD treatment. This article addresses use of the tool and its potential for improving addictions research and practice. Methods: During 2015–2017 we explored differences in RH scores in adolescent girls entering inpatient CD treatment at three points: 51 at admission, 39 at discharge, and 13 at 3 months post-discharge. Data were analyzed using a generalized linear mixed model to compare changes in domain scores of RH. Results: Changes in RH scores were significant in the friend domain, but not the mentor and community domains. The RHI-Y shows promise in discerning RH change during transitions in CD treatment. 相似文献
94.
Calm to chaos: Engaging undergraduate nursing students with the complex nature of interruptions during medication administration 下载免费PDF全文
Carolyn Hayes RN BHSc Debra Jackson RN PhD FACN Patricia M. Davidson RN PhD John Daly RN PhD FACN Tamara Power RN PhD 《Journal of clinical nursing》2017,26(23-24):4839-4847
95.
Mario Amore Cecchini Maria Paula Foss Vitor Tumas Flávia A.P. Patrocinio Rodolfo D. Chiari-Correia Nathalia Novaretti Tamara R. Brozinga Valéria Santoro Bahia Leonardo Cruz de Souza Henrique Cerqueira Guimarães Paulo Caramelli Thais Bento Lima-Silva Luciana Cassimiro Sonia Maria Dozzi Brucki Ricardo Nitrini Sergio Della Sala Mario A. Parra Mônica Sanches Yassuda 《International journal of geriatric psychiatry》2020,35(11):1331-1340
96.
97.
Dora Fabijanovic Iris Zunic Tamara Nikuseva Martic Faruk Skenderi Ljiljana Serman Semir Vranic 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2016,124(11):942-949
Germ cell tumors of the testis are a heterogeneous group of neoplasms that affect male adolescents and young adults. Wnt signaling pathway components have been shown to be actively involved in normal and malignant germ cell differentiation and progression. In this study, we aimed to explore the expression patterns of the secreted frizzled‐related protein (SFRP) and Disheveled protein family (DVL) in a subset of testicular germ cell tumors. Eighty‐five formalin‐fixed, paraffin‐embedded tissue samples of the primary germ cell tumors of the testis were stained against SFRP1, SFRP3, DVL1, and DVL2 proteins using immunohistochemistry. SFRP1 and SFRP3 exhibited lower expression in both seminomas and mixed/non‐seminomatous tumors, compared with atrophic/benign tissue (p < 0.001). SFRP3 expression was lower than SFRP1 expression within the seminoma group (p = 0.004), but not within the mixed/non‐seminomatous group (p = 0.409). The majority of the tested cases (27/28, 96%) exhibited low DVL1 protein expression (median 0%, range 0–90%). In contrast, 20 out of 22 tested cases (91%) exhibited strong expression of DVL2 protein (median 80%, range 0–100%). No significant difference in DVL1 and DVL2 protein expression was observed between seminomas and mixed/non‐seminomatous tumors (p = 0.68 and 0.29). The secreted frizzled‐related protein and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors. 相似文献
98.
99.
100.
Rusman Tamara John Marie-Luise B. van der Weijden Mignon A. C. Boden Bouke J. H. van der Bijl Carmella M. A. Bruijnen Stefan T. G. van der Laken Conny J. Nurmohamed Mike T. van der Horst-Bruinsma Irene E. 《Clinical rheumatology》2020,39(5):1521-1529
Clinical Rheumatology - The primary aim is to evaluate signs of inflammation on MRI of sacroiliac joints (SIJ)/spine in inflammatory back pain (IBP) patients suspected of nr-axSpA with high disease... 相似文献