排序方式: 共有90条查询结果,搜索用时 15 毫秒
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Banafsheh Kadkhodaei Alexandra Alvarsson Nicoletta Schintu Daniel Ramsk?ld Nikolaos Volakakis Eliza Joodmardi Takashi Yoshitake Jan Kehr Mickael Decressac Anders Bj?rklund Rickard Sandberg Per Svenningsson Thomas Perlmann 《Proceedings of the National Academy of Sciences of the United States of America》2013,110(6):2360-2365
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Validation of a Novel Digital Tool in Automatic Scoring of an Online ECG Examination at an International Cardiology Meeting 下载免费PDF全文
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Mehrnaz Rasoolinajad Nasrin Abedinia Ahmad Ali Noorbala Minoo Mohraz Banafsheh Moradmand Badie Abdulqader Hamad Leyla Sahebi 《AIDS and behavior》2018,22(12):3773-3782
People living with HIV/AIDS (PLHA) face several challenges in terms of the medical management of their disease. Alongside this are stigma, discrimination and psychosocial issues associated with HIV infection. In this study, the relationships associated with HIV-related stigma, mental health and quality of life for HIV-positive patients were investigated. This cross-sectional study examined a sample of 450 HIV positive patients from the Infectious Diseases and Behavioral Health Clinic of Imam Khomeini Hospital in the city of Tehran, Iran. PLWHA completed Socio-Demographic Characteristics, Berger Scale Stigma (BSS), General Health Questionnaire (GHQ-28), WHO Quality of life-BREF (WHOQOL-BREF) and Philips Social Support Appraisals (SSA). Stigma was significantly correlated with psychological variables, social support, and quality of life. A prevalence of psychiatric disorders was reported by 78.8%. Findings suggested that psychosocial interventions reduce HIV related stigma, address psychological disorders and build social support to improve quality of life for people living with HIV. 相似文献
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Ali Bidari Morteza Hassanzadeh Banafsheh Ghavidel Parsa Nahid Kianmehr Ali Kabir Sara Pirhadi Mohammad Sayfi Mehrangiz Toutounchi Fariba Fattahi Fereidoon Zandi Karimi 《Rheumatology international》2013,33(12):2999-3007
The aim of this study was to validate the 2010 American College of Rheumatology (ACR) preliminary criteria for fibromyalgia (FM) in an Iranian population. In this multicenter prospective study, we enrolled 168 FM patients and 110 controls. All participants underwent dolorimetry examination by study assessors and completed a questionnaire containing variables of both the ACR 2010 preliminary and ACR 1990 criteria. We compared the performance of the ACR 2010 criteria with the expert diagnosis as well as the ACR 1990 criteria. Receiver operator characteristic analyses and Youden index were used to evaluate the test characteristics of a set of different cutoff points for two subcomponents of ACR 2010 criteria including widespread pain index (WPI) and symptom severity (SS) scale. Considering expert diagnosis as the gold standard, the ACR 2010 criteria showed comparable specificity with ACR 1990 (92.8 vs. 88.3 %, P = 0.073), but lower sensitivity (58.9 vs. 71.4 %, P = 0.003) and a tendency for lower accuracy (72.4 vs. 78.4 %, P = 0.105). Applying the ACR 1990 criteria as the gold standard, we observed a trend toward an increase in overall accuracy (72.4 vs. 79.1 %, P = 0.064). Optimal test characteristics were achieved for WPI ≥6 and SS scale score ≥4 and improved sensitivity and accuracy of ACR 2010 criteria when compared to expert, 76.1 and 81.7, respectively. The preliminary ACR 2010 criteria performed less desirably in terms of sensitivity in our set of Iranian patients. Selecting lower cutoff points as WPI ≥6 and SS scale score ≥4 improved the diagnostic values of the criteria. 相似文献
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Nasser Shakhssalim Kobra Roohi Gilani Mahmoud Parvin Peyman Mohammadi Torbati Amir H. Kashi Mohaddeseh Azadvari Banafsheh Golestan Abbas Basiri 《Urological research》2011,39(1):1-7
The aim of this study is to investigate the serum levels of parathyroid hormone (PTH), calcitonin, 1,25 (OH)2 vitamin D3, estradiol and testosterone in male patients with active renal calcium stone disease compared with controls and
investigate their relationship with serum/urinary biochemistry. Male active renal calcium stone formers (ASF) were enrolled
from December 2008 to April 2009. Controls were selected from age and sex matched individuals. Two 24-h urine samples and
a blood sample were withdrawn from each participant while they were on free diet. Serum 1,25 (OH)2 vitamin D3 levels in the ASF and control groups were 127 ± 40 and 93 ± 35 pmol/l (p < 0.001). Serum levels of PTH, calcitonin, estradiol and testosterone were not statistically different between the ASF and
control groups (all p > 0.05). Serum 1,25 (OH)2 vitamin D3 was associated with higher urinary excretion of calcium and phosphorus in ASF patients. Serum levels of calcitonin
were related to less urinary excretion of calcium in the control group. Serum testosterone was related to higher urinary excretion
of uric acid in ASF patients and to higher urinary excretion of oxalate in the control group. 1,25 (OH)2 Vitamin D3 is an important hormone in the pathogenesis of recurrent renal calcium stone disease and could increase renal
stone risk by increasing the urinary excretion of calcium and phosphorus. There is a possibility of testosterone involvement
in the pathogenesis of renal stones through higher urinary uric acid and oxalate excretion. 相似文献
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Morphine is an analgesic widely used to alleviate cancer pain. In addition, the perioperative management of pain in cancer
surgery patients most often includes opioids. However, there are reports that these drugs may alter cancer recurrence or metastasis.
Several mechanisms have been proposed, such as the modulation of the immune response or cellular pathways that control the
survival and migratory behavior of cancer cells. The published literature, however, presents some discrepancies, with reports
suggesting that opioids may either promote or prevent the spread of cancer. It is of great importance to determine whether
opioids, in particular the most widely used, morphine, may increase the risk of metastasis when used in cancer surgery. This
review examines the available data on the effects of morphine which influence cancer metastasis or recurrence, including immunomodulation,
tumor cell aggressiveness, and angiogenesis, with special emphasis on recently published clinical and laboratory based studies.
We further discuss the parameters that may explain the difference between reports on the effects of morphine on cancer. 相似文献
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Ali Noorafshan Banafsheh Esmail-Zadeh Soghra Bahmanpour Aghdas Poost-Pasand 《Indian journal of gastroenterology》2005,24(3):104-107
BACKGROUND: Diabetes mellitus is associated with biochemical, physiological and pathologic alterations in the liver. We measured changes in structure of rat liver after streptozotocin injection, using stereology. METHODS: Livers of 36 streptozotocin-injected rats were removed after 4, 8 and 12 weeks. Liver volume and weight were measured, and volume-weighted mean volume of hepatocytes and their nuclei were estimated in periportal (Z1), interstitial (Z2) and perivenous (Z3) zones of liver acini. Volume of liver sinusoids was also estimated. RESULTS: Mean volume and weight of the liver were reduced by 15% and 12%, respectively at 4 and 8 weeks after injection. Mean hepatocyte volumes were reduced by approximately 30%, 31% and 24% in Z1, Z2 and Z3 at 4 weeks, 19% and 24% in Z2 and Z3 at 8 weeks, and 14% in Z1 at 12 weeks. Mean volume of hepatocyte nuclei was reduced by approximately 18% and 20% in Z2 and Z3 at 4 weeks, 23% in all three zones at 8 weeks, and 18%, 15% and 13% in Z1, Z2 and Z3, respectively, at 12 weeks. The absolute volume of the sinusoids decreased by 16.5% only at 4 weeks. CONCLUSION: Streptozotocin injection leads to early reduction in volume of hepatocytes, their nuclei and sinusoids in rat liver. 相似文献