罕见小肠囊腺瘤1例报道

SUMMARY In recent years, there have been more and more reports about cystadenoma. Cystadenoma can occur in many parts of the body, and cystadenoma in different parts may show different clinical symptoms, however, some patients with cystadenoma have no symptoms. The vast majority of cystadenomas are benign lesions, but a small number of cystadenomas can be malignant. For example, a small number of ovarian cystadenomas and pancreatic cystadenomas may be malignant. This study reported a patient with small intestinal cystadenoma diagnosed by pathology. The patient's physical examination revealed a lesion in the left upper abdomen. He had only abdominal distension and no other discomfort. His laboratory examination results were basically normal, i.e. blood routine, urine routine, stool routine, liver function, kidney function, myocardial enzyme, tumor marker, etc. The patient underwent sectional small intestine resection and the pathological sample was analyzed. The histological findings of the resected intestinal sample were consistent with cystadenoma. Computed tomography scan of the abdomen was performed 4 months after the surgery. No recurrence of the tumor was found. The patient recovered in good condition. By consulting the literature, I found very few reports of small intestinal cystadenoma before, it was very rare. This article described the clinical manifestation, diagnosis and differential diagnosis, treatment and prognosis of a case of small intestinal cystadenoma, it suggested that cystadenoma can occur in the small intestine, other than the ovary, pancreas, liver, lung, thyroid, prostate, seminal vesicle, skin, etc. The cystadenoma in small intestine is easy to be mistaken with other tumors, such as small intestine stromal tumor, small intestine adenocarcinoma, small intestine lipoma, small intestine hemangiomas, etc., and it is difficult to fully confirm through imaging examinations, such as computed tomography and magnetic resonance imaging. Laparotomy and histopathological examination are necessary before definitive diagnosis. This disease can be treated by small bowel resection at the affected region and good prognosis can be achieved.     

骨转移癌疼痛的治疗进展

骨转移癌是肿瘤患者常见并发症,其发病率占全身转移癌的15%~20%,仅次于肺及肝转移癌的发病率。易发生骨转移癌的恶性肿瘤包括肺癌、乳腺癌、前列腺癌等,而疼痛是骨转移癌最常见的临床症状,早期症状隐匿,随着病情进展,症状逐渐加重,晚期疼痛剧烈,给肿瘤患者的生存质量带来严重威胁。因此,本研究通过检索国内外文献,系统介绍了西医及中医治疗骨转移癌疼痛的现状,以期为骨转移癌疼痛的临床治疗提供建议和参考。     

肺腺癌摄取骨显像剂99mTC-MDP一例

骨外组织(包括肺癌组织)摄取骨显像剂99mTC-MDP曾有报道[1-5],但肺腺癌摄取99mTC-MDP,尚无报道,现将本例报告如下:1临床资料患者,女性,69岁。主因“胸痛”并胸透发现右肺阴影,于2004年7月24日入院。胸部CT示:右肺下叶致密肿块,大小为5.0 cm×2.8 cm,肿块累及胸膜,边缘清晰,并见浅分叶征,未见胸水;同时,在CT引导下,行胸穿取肺组织活检,病理结果示:低分化腺癌,免疫组化示:CK7( )、CK14(-);核素全身骨扫描示:前位及后位,在第8、9肋骨处,均有局限性放射性浓聚,两者相比较,后位较前位浓;SPECT胸部断层发现,在右肺中下部靠近后胸部有…     

8例恶性肿瘤125Ⅰ粒子种植近距离放疗后近期18F-FDG PET/CT影像表现

放射性粒子治疗恶性肿瘤已取得较大成绩,对其疗效评价主要依靠CT测量大小估算局部控制率等方法,缺乏肿瘤生物代谢特征,更缺乏对肿瘤再分期的评价.     

从痰论治高黏滞血症

从病理特性、实质研究、差异表现、治疗效果、痰瘀相关5个方面来论述高黏滞血症与痰证的相关性,提出从痰论治高黏滞血症的观点.     

益气破瘀法对狼疮鼠血清IL-10与ILN-γ及肾脏病理的影响

目的:观察益气破瘀法对NZB/W F1狼疮鼠的疗效,并探讨其作用机制.方法:将NZB/W F1小鼠随机分为模型组、中药组、西药组与中西医结合组.分别以生理盐水、益气破瘀小复方和骁悉对其进行干预治疗.以双抗夹心ELISA法检测血清IL-10、IFN-γ水平,肾组织行常规HE染色.结果:中药组、西药组、中西医结合组与模型组相比,血清IL-10、IFN-γ均有显著降低(P＜0.01);各治疗组之间比较未见差异显著(P＞0.05).HE染色显示,中药组、西药组、中西医结合组肾脏病变与模型组相比,系膜细胞增生、系膜基质增宽等情况较轻,内皮下免疫复合物沉积较少,其中以中西医结合组病变最轻.结论:益气破瘀法能明显降低狼疮鼠血清IL-10、IFN-γ水平,延缓肾脏损害.采用中西医结合治疗的效果优于单用中药和单用西药.     

过氧化物还原酶4在胃癌中的表达及其意义的生物信息学研究

目的：通过生物信息学途径探究过氧化物还原酶4(peroxiredoxin 4,PRDX4)在胃癌（gastric cancer, GC）中的表达及其意义,并通过免疫组织化学检测63例GC患者肿瘤组织中PRDX4的表达情况。方法：从Ualcan数据库获取正常胃组织及原发性胃癌组织PRDX4表达数据,在LinkedOmics中检索PRDX4的共表达基因,并通过GO富集分析、KEGG通路分析确定这些基因参与的生物学过程及功能,利用STRING数据库分析相关基因编码蛋白的互作网络。最后利用GEPIA数据库分析PRDX4表达与胃癌患者预后的关系;纳入2022年1月至2022年10月在成都医学院第一附属医院就诊的63例GC患者,通过MaxVision法对GC肿瘤组织及其周围正常组织进行PRDX4表达情况的免疫组化染色并观察结果。结果：Ualcan数据库显示,与周围正常胃组织相比,PRDX4在GC组织中高度表达（P <0.05）,但尚未发现其表达与性别、肿瘤分化程度、肿瘤大小和淋巴结转移有关联。同时检索出PRDX4共表达基因主要与生物调节、代谢过程、刺激反应等分子生物学过程存在紧密联系,并与E...     

乌头,从毒药到良药

《三国演义》第七十五回中描述了华佗身负青囊,自江东乘小舟翩然而至,说“天下英雄关将军乃弩箭所伤,其中有乌头之药”,如不及时手术,手臂就会残废。紧接着又刻画了关羽一面下棋,一面接受神医华佗刮骨疗毒的精彩情节。