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661.
Dilip Kumar Malipatlolla Sravani Devarakonda Piyush Patel Fei Sjberg Ana Rascn Rita Grandr Viktor Skokic Marie Kalm Jolie Danial Eva Mehdin Malin Warholm Henrietta Norling Andrea Stringer Malin E. V. Johansson Margareta Nyman Gunnar Steineck Cecilia Bull 《International journal of molecular sciences》2022,23(1)
Dietary fiber is considered a strong intestinal protector, but we do not know whether dietary fiber protects against the long-lasting mucosal damage caused by ionizing radiation. To evaluate whether a fiber-rich diet can ameliorate the long-lasting pathophysiological hallmarks of the irradiated mucosa, C57BL/6J mice on a fiber-rich bioprocessed oat bran diet or a fiber-free diet received 32 Gray in four fractions to the distal colorectum using a linear accelerator and continued on the diets for one, six or 18 weeks. We quantified degenerating crypts, crypt fission, cell proliferation, crypt survival, macrophage density and bacterial infiltration. Crypt loss through crypt degeneration only occurred in the irradiated mice. Initially, it was most frequent in the fiber-deprived group but declined to levels similar to the fiber-consuming group by 18 weeks. The fiber-consuming group had a fast response to irradiation, with crypt fission for growth or healing peaking already at one week post-irradiation, while crypt fission in the fiber-deprived group peaked at six weeks. A fiber-rich diet allowed for a more intense crypt cell proliferation, but the recovery of crypts was eventually lost by 18 weeks. Bacterial infiltration was a late phenomenon, evident in the fiber-deprived animals and intensified manyfold after irradiation. Bacterial infiltration also coincided with a specific pro-inflammatory serum cytokine profile. In contrast, mice on a fiber-rich diet were completely protected from irradiation-induced bacterial infiltration and exhibited a similar serum cytokine profile as sham-irradiated mice on a fiber-rich diet. Our findings provide ample evidence that dietary fiber consumption modifies the onset, timing and intensity of radiation-induced pathophysiological processes in the intestinal mucosa. However, we need more knowledge, not least from clinical studies, before this finding can be introduced to a new and refined clinical practice. 相似文献
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Radiative transfer computations are carried out to describe the intrinsic and effective optical properties of light diffusing and absorbing materials consisting of anatase titania pigments hosted in an electrolyte medium. The intrinsic visible absorption of some of the pigments has been increased by coating them with an absorbing dye monolayer. A multiple scattering approach is applied to compute average path-length parameters and forward-scattering ratios used in four-flux radiative transfer calculations. It is shown that the effective absorption coefficient of the inhomogeneous medium is maximized when the size of the pigments is around 12 nm in diameter, and the effective scattering coefficient is optimized for diameters of the pigments around 250 nm. The intrinsic solar absorptance of the medium is optimized when the diameter of the pigments is around 60 nm. 相似文献
664.
The preparation of starch carbamates of wrinkled pea starch in homogeneous phase catalysed by dibutyltin dilaurate in DMSO as solvent is described. The empfloyed isocyanates have linear alkyl chains with 7, 9, 11, 15 or 18 carbon atoms. Starch carbamates with equal degrees of substitution and different alkyl chains lengths were synthesised in a reaction flask. The preparation of carbamates with equal alkyl chain length and different degrees of substitution was also possible. The structures of the polymers were characterised by elemental analysis, IR‐ and 1H‐NMR‐spectroscopy. The behaviour of the prepared starch carbamates under thermal loading was investigated by using Differential Scanning Calorimetry (DSC) and a hot press. In addition, for 1‐undecyl isocyanate the starch carbamate was prepared both in a kneader and an extruder. The differences in reaction conditions and the results were discussed. 相似文献
665.
Randi Seljsen Gunnar B Bengtsson Halldor Hoftun Gjermund Vogt 《Journal of the science of food and agriculture》2001,81(4):436-447
Carrots harvested by hand or machine and given additional mechanical stress by shaking in a transport simulator were analysed for taste, flavour and content of sugars, terpenes, 6‐methoxymellein and ethanol as well as for ethylene production and respiration. Carrots stressed by shaking had higher ethylene production and respiration, higher content of ethanol and 6‐methoxymellein and lower levels of total terpenes, several individual terpenes and sugars. This corresponded to a higher sensory score for ethanol flavour and odour, bitter taste, earthy flavour, terpene flavour, aftertaste and sickeningly sweet taste and a lower score for acidic taste and sweet taste as measured by an expert taste panel. Ethanol content was highly correlated with ethanol flavour and odour and sickeningly sweet taste. Of five varieties tested, ‘Bolero’ ‘Panter’ and ‘Yukon’ were most sensitive to mechanical stress, whereas ‘Napa’ and ‘Newburg’ were most resistant. Hand‐harvested carrots were not significantly different from machine‐harvested carrots as regards chemical or sensory variables. Principal component analysis showed only slightly different placing of these samples in the score plot. A digital carrot could monitor the degree of mechanical stress to which the carrots were subjected. © 2001 Society of Chemical Industry 相似文献
666.
Two spring and two winter wheat cultivars were investigated for bread volume, grain protein concentration and mixogram index. Data for the weather conditions—mean day temperature per month, precipitation per month, and sun hours per month—were collected for the same period. Relationships between the quality factors were studied as well as relationships between these factors and weather conditions. The bread volumes varied from 910 to 1415 ml, and from 630 to 1067 ml for the spring and winter wheats, respectively. The grain protein concentrations were between 11.1 and 14.9% for the spring wheats, and between 10.6 and 16.7% for the winter wheats. Mixogram indexes varied from 110 to 156, and from 89 to 139, for spring and winter wheats, respectively. A strong correlation was found between the bread-making quality and the grain protein concentration and quality. The grain protein concentration and mixogram index accounted for 19% and 15% of the variation in bread volume, respectively. The climatic variables influenced on bread volume, and grain protein concentration and quality. The temperature, specially during the grain filling period, was the most important weather parameter, explaining 34% of the variation in grain protein concentration and 49% of the variation in mixogram index in spring wheat. The influence of the weather on the quality parameters, were more complex in the winter wheats. © 1998 Society of Chemical Industry. 相似文献
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669.
Soham Mukherjee Sarmad Naim Katea Emille M. Rodrigues Carlo. U. Segre Eva Hemmer Peter Broqvist Håkan Rensmo Gunnar Westin 《Small (Weinheim an der Bergstrasse, Germany)》2023,19(1):2203331
Nanocrystalline ZnO sponges doped with 5 mol% EuO1.5 are obtained by heating metal–salt complex based precursor pastes at 200–900 °C for 3 min. X-ray diffraction, transmission electron microscopy, and extended X-ray absorption fine structure (EXAFS) show that phase separation into ZnO:Eu and c-Eu2O3 takes place upon heating at 700 °C or higher. The unit cell of the clean oxide made at 600 °C shows only ≈0.4% volume increase versus undoped ZnO, and EXAFS shows a ZnO local structure that is little affected by the Eu-doping and an average Eu3+ ion coordination number of ≈5.2. Comparisons of 23 density functional theory-generated structures having differently sized Eu-oxide clusters embedded in ZnO identify three structures with four or eight Eu atoms as the most energetically favorable. These clusters exhibit the smallest volume increase compared to undoped ZnO and Eu coordination numbers of 5.2–5.5, all in excellent agreement with experimental data. ZnO defect states are crucial for efficient Eu3+ excitation, while c-Eu2O3 phase separation results in loss of the characteristic Eu3+ photoluminescence. The formation of molecule-like Eu-oxide clusters, entrapped in ZnO, proposed here, may help in understanding the nature of the unexpected high doping levels of lanthanide ions in ZnO that occur virtually without significant change in ZnO unit cell dimensions. 相似文献
670.
Hydropower is an important tool in the struggle for low-emission power production. In the Nordic countries, hydropower operating conditions are expected to change and work more in conjunction with intermittent power production. This in turn might increase the amount of hydropeaking events in the reaches downstream of hydropower plants. The current work investigates the influence of highly flexible, high-frequency hydropeaking on the hydrodynamics in the downstream reach. By quantifying four different dynamic stages in the study reach, the influence of the hydropeaking frequencies was investigated in the bypass reach of the Stornorrfors hydropower plant in the river Umeälven in northern Sweden. The hydrodynamics in the study reach were numerically modelled using the open source solver Delft3D. Eight different highly flexible future hydropeaking scenarios, varying from 12 to 60 flow changes per day, were considered. A method for identifying four hydropeaking stages—dewatering, dynamic, alternating and uniform —was introduced. The hydropeaking frequency directly decided the stage in most of the study reach. Furthermore, a Fourier analysis showed a significant difference between the stages and their corresponding power spectra. The classification of stages put forward in this work provides a novel, simple method to investigate the hydrodynamics due to hydropeaking in a river reach. 相似文献