CASE环境工具支持接口

本文首先简要讨论了ＣＡＳＥ环境工具技术接口的发展情况，然后具体讨论了工具支持接口的需求：分布式数据库、分布式体系结构和高级用户接口，由于分布式数据库是ＣＡＳＥ环境工具技术接口的核心，因而着重对它进行了讨论。     

Regulation of Kv4.2 and Kv1.4 K+ channel expression by myocardial hypertrophic factors in cultured newborn rat ventricular cells

Postnatal development and myocardial hypertrophy are associated with alterations in cardiac voltage-gated K+ channels. To investigate mechanisms underlying this K+ channel remodeling, expression of Kv4.2 and Kv1.4 K+ channel alpha-subunits was examined in cultured newborn rat ventricular myocytes by Western blot analysis using polyclonal antibodies against each of the subunits. At day 5 of cell culture, Kv1.4 protein was expressed at higher level than Kv4.2; as the age of culture progressed, Kv1.4 was significantly diminished while Kv4.2 increased with time in culture and became the predominant K+ channel protein. Such K+ channel isoform switch from Kv1.4 to Kv4.2 resembles that of the development in vivo. A 72-h treatment with exogenous triiodothyronine (T3, 0.1 microM) to cultured neonatal myocytes enhanced the expression of Kv4.2 by 73% and decreased the Kv1.4 expression by 22%. The effects of T3 were associated with an increase in the protein-to-DNA ratio indicating myocyte hypertrophy. On the other hand, a 72-h treatment with cardiac non-myocyte cell (NMC)-conditioned growth medium (NCGM) or phenylephrine (20 microM) induced similar cell hypertrophy, but in sharp contrast to T3, both markedly suppressed the Kv4.2 channel protein level. In addition, the trophic and the Kv4.2-downregulating effects of NCGM could be mimicked by exogenous endothelin-1 (0.1 microM), a paracrine factor secreted from cardiac NMCs. Our observations for the first time suggest that cardiac Kv4.2 and Kv1.4 K+ channel alpha-subunits are differentially regulated by a variety of myocardial hypertrophic factors. That T3 accelerated the developmental K+ channel isoform switch from Kv1.4 to Kv4.2 in vitro indicates the critical importance of thyroid hormone in postnatal K+ channel remodeling. Cardiac NMCs and alpha-adrenoceptor activation may contribute to the reduced outward K+ channel density in hypertrophied cardiomyocytes.     

层次式级联多网络模型及其性能

本文提出了一种层次式级联多网络结构，论述了其训练算法，并验证了该结构的收敛性。这种结构在处理高阶非线性分布数据的分类问题方面具有优良的性能，用北京谱仪事例过滤进行性能测试结果表明，其训练和泛化性能都优于单个ＢＰ网络。     

广义左,右线性递归规则组改写

本文从左，右线性递归规则组的定义出发，提出了广义左，右线性递归规则组的定义，放宽了左，右线性递归规则组寻规则形式的限制，扩展了Ｕｌｌｍａｎ提出的左，右线性递归规则组改写方法的适用范围。本文证明了由广义左，右线性递归规则组向左，右线性规则组转换的相容性，并给出了具体的转换算法。     

面向对象工程数据库管理系统O2S并发事务模型

Ｏ２Ｓ是我们在ＳＵＮ工作站上开发的一面向对象工程数据库管理。本文针对工程应用域事务的嵌套性，长时性，数据库逻辑分区性和涉及数据量大的四个显著特点，阐述了Ｓ２Ｓ的事务管理模型。对工程域事务的管理，数据库的恢复和封锁技术进行了讨论。     

ConcurrentC语言在分布式系统上的一种高效实现

本文介绍了ＣｏｎｃｕｒｒｅｎｔＣ语言在一分布式系统上的实现。该实现使用了不同于预编译法的编译器的构造方法，同时将Ｃｏｎｃｕｒｒｅｎｔ Ｃ语言中的进程实现为ＵＮＩＸ进程中的用户级线索，是ＣｏｎｃｕｒｒｅｎｔＣ语言在分布式系统上的一种高效实现。     

Nuclear proteins from liver and kidney bind a 37 bp sequence in the 5' upstream region of the mGAT1 gene

The mouse GABA transporter (mGAT1) gene has been shown to be exclusively expressed in brain by Northern and Western blot analyses. The interactions between the 5' flanking region of the mGAT1 gene and nuclear proteins from different mouse tissues were studied by means of gel-shift assay. Our results show that nuclear protein factors from non-nervous tissues can specifically recognize a 37 bp sequence that is conserved in the 5' flanking region between the human and mouse GAT1 genes. Similar nuclear protein factors were also found to exist in rat, rabbit and pig.     

火箭燃气射流对斜板冲击流场的数值模拟

采用高精度，高分辨率的二阶ＴＶＤ有限体积方法，对二维无粘射流冲击斜板的复杂流动场进行了数值模拟，得到了和实验规律相一致的计算结果。