斗晏水电站混凝土面板堆石坝趾板设计

阐述了江西省重点建设项目斗晏水电站混凝土面板堆石趾板设计，并重点介绍较大断层上趾板设计处理方式。     

中国城市水利面临的严峻形势

我国许多城市的发展特点是城市水利的发展现状令人堪忧，本文从城市人口、水资源、防洪、水环境、管理体制等方面分析了我国城市水利面临的严峻形势，并就水资源、城市防洪标准等方面提出了相应的对策。     

沥青延度与流变特性关系研究分析(一)

通过对两种基质沥青进行不同温度及不同速率下的延度试验，找出它们的流变特性，并从微观上进行分析，最后与路用性能相联系，又通过TFOT试验找出流变特性对耐老化性之间的关系，最后得出，沥青的流变特性可通过延度试验来表征，它能够较好地反映沥青的路用性能。     

气动汽车发动机工作循环的理论分析

城市污染和石油资源的匮乏使得人们在不断地寻求不用直接燃油或燃气的新型动力机械。气动汽车发动机就是其中的一类,它是以压缩空气、液氮或液态空气作为工作介质,可以实现零排放,是真正意义的环保动力。从理论分析的角度,对压缩空气发动机和液氮发动机的工作循环进行了分析讨论,采用不同概念计算了两者的可用能,并着重分析了膨胀初始压力和温度对输出功的影响,还探讨了液氮发动机工作循环的优化途径。     

纵横波测井资料在储层评价中的应用

将弹性波基础理论，Gasman理论，Biot理论和实验研究结果相结合，探讨了沉积岩地层中速度和弹性模量，弹性模量和孔隙度，剪切模量和孔隙度，速度和孔隙度，孔隙度和Biot系数之间的关系，利用从各种声学测井资料中提取出的P波和S波时差（或速度）定量评价地层孔隙度和骨架物质，辅以泥质指示测井曲线，可以计算地层孔隙度，饱和度，岩性等参数，在M，Krief方法的基础上，采用优化算法寻求适合于任何岩性地层的孔隙度与Biot系数之间的关系式，提高了Biot系数的计算精度，该评价方法有坚实的实验基础和理论基础，评价结果与实验室岩心分析数据吻合。     

中国石油未来油气勘探重点领域分析

根据近几年来的研究认识与勘探成果分析,未来几年中国石油油气勘探主要集中于如下五大重点领域:大面积低渗透岩性油气藏、成熟区复杂隐蔽油气藏、前陆盆地复杂构造油气藏、海相碳酸盐岩油气藏和渤海湾滩海第三系油气藏。     

硬脆性无机材料激光成形加工研究与应用现状

硬脆性无机材料激光成形加工是激光加工技术最有前途的领域之一。本文综述了国内外在硬脆性无机材料的激光成形加工方面的研究成果和应用状况，并展望了无机材料激光成形加工的研究与应用前景。     

MEMS光开关及其与光纤组装方式的研究

光开关是一种在光路中应用极其广泛的光无源器件,可用于扫描、投影、通讯等多种不同的领域,其中用于全光通讯中连接光纤之间的光开关日渐成为人们关注的焦点.高性能、低成本、又能大量生产的MEMS光开关很好地满足了全光网络对器件的要求.本文对这种MEMS光纤光开关的类型、特点以及研究现状进行了介绍,并给出了MEMS光开关与输入输出光纤的组装与自组装以及主要方式.     

Analysis on the effectiveness of the 20-H rule for printed-circuit-board layout to reduce edge-radiated coupling

This paper presents the quantified study of the electromagnetic radiation mechanism of the 20-H rule using a numerical approach that has not yet been systematically addressed. The 20-H rule is a rule-of-thumb layout technique recommended to minimize radiated fields propagating from the edges of a printed circuit board (PCB) coupling onto nearby structures. Propagating electromagnetic fields may corrupt adjacent cable assemblies, sheet metal enclosures, and aperture openings. The magnitude of this design rule is investigated using the full-wave finite-difference time-domain (FDTD) method. An analysis on whether benefits exist from use of this rule is examined and under what conditions the rule is valid when correctly implemented. The purpose of this paper is to provide insight into the validity of the 20-H rule, recognizing that every PCB will have different simulation results. FDTD is used to capture a snapshot view of field propagation. This view allows one to determine the validity of the 20-H rule at a single point of time within a dynamic structure and what may be expected when digital components are finally added to a PCB assembly, which generally negates simulated results.     

Influence of CYP3A5 polymorphism on tacrolimus blood concentrations in renal transplant patients

Objective Tacrolimus is an immunosuppressive drug with narrow therapeutic range and wide interindividual variation in its pharmacokinetics. Tacrolimus is a substrate of cytochrome P450(CYP)3A5. The aim of this study was to evaluate whether the A6986G polymorphism is associated with tacrolimus concentration /dose ratio. Methods Fifty-two Chinese renal transplant patients were enrolled in this study. Their body weight, dosage and concentration of tacrolimus were observed. CYP3A5 genotype was determined by polymerase chain reaction followed by restriction fragment length polymorphism analysis. Results A significant association was found between tacrolimus levels per dose/kg/d and CYP3A5 gene A6986G polymorphism (P<0.001). The CYP3A5 * 3 * 3 patients have a significantly higher tacrolimus level/dose than CYP3A5 * 1 * 1 and CYP3A5 * 1 * 3. Conclusions CYP3A5 gene A6986G polymorphism is associated with tacrolimus pharmacokinetics and dose requirements. Pharmacogenetic methods could be employed prospectively to help the dose selection and to individualize immunosuppressive therapy according to the result. Foundation item: Project (03GZ3072) supported by the Science and Technology Department of Hunan Province; project (2004035206) supported by the China Postdoctoral Foundation and project (30300383) supported by the National Natural Sciences Foundation of China