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81.

Context

Adopting IT innovation in organizations is a complex decision process driven by technical, social and economic issues. Thus, those organizations that decide to adopt innovation take a decision of uncertain success of implementation, as the actual use of a new technology might not be the one expected. The misalignment between planned and effective use of innovation is called assimilation gap.

Objective

This research aims at defining a quantitative instrument for measuring the assimilation gap and applying it to the case of the adoption of OSS.

Method

In this paper, we use the theory of path dependence and increasing returns of Arthur. In particular, we model the use of software applications (planned or actual) by stochastic processes defined by the daily amounts of files created with the applications. We quantify the assimilation gap by comparing the resulting models by measures of proximity.

Results

We apply and validate our method to a real case study of introduction of OpenOffice. We have found a gap between the planned and the effective use despite well-defined directives to use the new OS technology. These findings suggest a need of strategy re-calibration that takes into account environmental factors and individual attitudes.

Conclusions

The theory of path dependence is a valid instrument to model the assimilation gap provided information on strategy toward innovation and quantitative data on actual use are available.  相似文献   
82.
For evaluating visual-analytics tools, many studies confine to scoring user insights into data. For participatory design of those tools, we propose a three-level methodology to make more out of users' insights. The Relational Insight Organizer (RIO) helps to understand how insights emerge and build on one each other.  相似文献   
83.
Massimo Ficco  Stefano Russo 《Software》2009,39(13):1095-1125
Location‐aware computing is a form of context‐aware mobile computing that refers to the ability of providing users with services that depend on their position. Locating the user terminal, often called positioning, is essential in this form of computing. Towards this aim, several technologies exist, ranging from personal area networking, to indoor, outdoor, and up to geographic area systems. Developers of location‐aware software applications have to face with a number of design choices, that typically depend on the chosen technology. This work addresses the problem of easing the development of pull location‐aware applications, by allowing uniform access to multiple heterogeneous positioning systems. Towards this aim, the paper proposes an approach to structure location‐aware mobile computing systems in a way independent of positioning technologies. The approach consists in structuring the system into a layered architecture, that provides application developers with a standard Java Application Programming Interface (JSR‐179 API), and encapsulates location data management and technology‐specific positioning subsystems into lower layers with clear interfaces. In order to demonstrate the proposed approach we present the development of HyLocSys. It is an open hybrid software architecture designed to support indoor/outdoor applications, which allows the uniform (combined or separate) use of several positioning technologies. HyLocSys uses a hybrid data model, which allows the integration of different location information representations (using symbolic and geometric coordinates). Moreover, it allows support to handset‐ and infrastructure‐based positioning approaches while respecting the privacy of the user. The paper presents a prototypal implementation of HyLocSys for heterogeneous scenarios. It has been implemented and tested on several platforms and mobile devices. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
84.
Extensible Markup Language (XML) and the XML Path Language (XPath) are introduced with software examples demonstrating how one can use them to write laboratory data management programs. Topics explored include XML document creation, manipulation, and searching. Programming examples make use of the Microsoft® XML Parser library and the Visual Basic programming language. The problem of managing microplate screening data is used as an illustration. Source code for all examples can be downloaded from http://www.labprogrammer.net.  相似文献   
85.
Providing appropriate methods to facilitate the analysis of time-oriented data is a key issue in many application domains. In this paper, we focus on the unique role of the parameter time in the context of visually driven data analysis. We will discuss three major aspects - visualization, analysis, and the user. It will be illustrated that it is necessary to consider the characteristics of time when generating visual representations. For that purpose we take a look at different types of time and present visual examples. Integrating visual and analytical methods has become an increasingly important issue. Therefore, we present our experiences in temporal data abstraction, principal component analysis, and clustering of larger volumes of time-oriented data. The third main aspect we discuss is supporting user-centered visual analysis. We describe event-based visualization as a promising means to adapt the visualization pipeline to needs and tasks of users.  相似文献   
86.
87.
Cytidine deaminase (CDA) is a cytosolic metalloprotein whose functional unit can be either a homotetramer (T-CDA) or a homodimer (D-CDA), depending on the species. In 1994, the first crystal structure of the dimeric Escherichia coli CDA has been published. However, a crystal structure of a tetrameric CDA was not determined until 2002. Prior to the disclosure of the experimentally elucidated structure of a tetrameric CDA, we derived a homology model of the human T-CDA employing the crystal structure of the dimeric E. coli CDA as a template. The comparison of our theoretical model with the crystal structure of the human T-CDA, subsequently published in 2004, validates our prediction: not only of the structural features of the monomer and the details of the binding site, but also the multimeric arrangement of the subunits were determined with high accuracy in our model. By means of a phylogenetic analysis conducted on CDAs from various organisms, we demonstrate that the E. coli CDA is one of the furthest known homologues of the human enzyme. Nonetheless, despite the evolutionary distance and, more importantly, the different multimeric arrangement of their functional units, the E. coli CDA proved to have all the necessary information to accurately infer the structure of its human homologue.  相似文献   
88.
In patients with severe drug-resistant partial epilepsy, undergoing Stereo-EEG investigations, spatial definition of the "epileptogenic area" is mainly based on spontaneous seizures recordings, but also on seizures induced by intracerebral electrical stimulation (ES). Only "trains" ES (TES, 50 pps) are currently used with this aim; "shocks" ES (SES, 1 pps) are principally applied to localize motor pathways. We have shown, during a prospective study concerning 10 temporal lobe epileptic patients, that SES could frequently induce seizures, especially when stimulation is applied in the anterior part of the Ammon's horn. Even if its efficacy seems lower than by TES, this kind of stimulation, in the majority of the cases, does reproduce isolated ictal subjective symptomatology, allowing the visualization of the progressive organisation of ictal electrical discharges, and avoids "unexpected" ("false positive"?) clinical responses.  相似文献   
89.
Spinal ganglion (SG) neurons are subdivided, on the basis of their cytoplasmic aspect at light and electron microscopy, into dark (D) and light (L) neurons. Numerous efforts have been made to find specific markers able to identify D and L neuronal cytotypes. The isolectin B4 (IB4), utilized to identify nonpeptidergic D neurons in mice, unfortunately, has not proved as effective in other species. The 200-kDa neurofilament protein (NF200) is considered as a typical marker of L neurons in the rat, cat, and chick. The aim of this study was to analyze the histological, morphometric, and neurochemical characteristic of NF200-immunoreactive (IR) horse SG neurons, to better characterize them morphologically and functionally. NF200-IR neurons showed two levels (strong and weak) of staining intensity. Most (84%) strongly stained NF200-IR neurons corresponded to L neurons, and showed similar bimodality as in the size distribution study, which seems to indicate a third population of neurons, in addition to the two populations (small and large) previously identified. In triple-staining experiments where NF200 was colocalized with IB4, substance P (SP), and neuronal nitric oxide synthase (nNOS) neuronal markers, most NF200-IR neurons were single stained. On the contrary, most IB4-, SP-, and nNOS-stained neurons were triple labeled and almost equally subdivided between strong and weak NF200-IR with the latter being always smaller in size than strong NF200-IR neurons. In conclusion, horse SG neurons display significant morphometric and neurochemical differences compared with those of rodents.  相似文献   
90.
An experimental evaluation of insulation effectiveness, pull-down times and effectiveness of a mechanical refrigeration unit was performed on five refrigerated panel vans. Additionally, a mapping of temperature variability in the cargo space was carried out during a simulated journey encompassing several door openings. The temperature variability measured in the vans was neither correlated to the effectiveness of the insulation nor the time required to achieve complete cooling of the cargo space. These criteria are common thermal performance indicators used to evaluate refrigerated vehicles in international standards. The efficiency of insulation was correlated to the pull-down times, presenting the possibility of calculating the former as a function of the latter. The temperature variability was correlated with the time required for the unit to recover temperature control after a door opening and the difference between the maximum and minimum temperatures reached during a door opening cycle.  相似文献   
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