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11.
In this study, we investigated surface and biological properties of Ag–Sr-doped mesoporous bioactive glass nanoparticle (Ag–Sr MBGN) loaded chitosan/gelatin coatings deposited by electrophoretic deposition (EPD) on 316L stainless steel. The EPD parameters, that is, deposition time, applied voltage, and distance between the electrodes was optimized by the Taguchi design of experiment (DoE) approach. Scanning electron microscopy (SEM) images illustrated the spherical morphology of the synthesized Ag–Sr MBGNs with the mean particle size of 160 ± 20 nm. Energy-dispersive X-ray (EDX) spectroscopy results confirmed the presence of Ag and Sr in the synthesized MBGNs. Optimum EPD parameters determined by DoE approach were 5 g/L of Ag–Sr MBGNs, deposition time of 5 min, and applied voltage of 30 V. SEM images confirmed that the coatings were fairly homogenous. Fourier-transform infrared spectroscopy and EDX results confirmed the presence of chitosan, gelatin, and Ag–Sr MBGNs in the coatings. Chitosan/gelatin/Ag–Sr MBGN composite coatings exhibited suitable wettability for the protein attachment and proliferation of osteoblast cells. The composite coatings exhibited suitable adhesion strength with the substrate. The coatings developed HA crystals upon immersion in simulated body fluid. The results of the turbidity test confirmed that the coatings are antibacterial to the Escherichia coli cells.  相似文献   
12.
The dynamic pressure distribution on a rectangular plate attached to a rigid wall and supporting an infinitely large extent of fluid subjected to a harmonic ground excitation is evaluated in the time domain. Governing equations for the fluid domain are set considering the compressibility of the fluid with negligibly small change in density and a linearized free surface. A far boundary condition for the three-dimensional fluid domain is developed so that the far boundary is truncated at a closer proximity to the structure. The coupled problem is solved independently for the structure and the fluid domain by transferring the acceleration of the plate to the fluid and pressure of the fluid to the plate in sequence. Helmholtz equation for the three-dimensional fluid domain and Mindlin's theory for the two-dimensional plate are used for the solution of the interacting domains. Finite element technique is adopted for the solution of this problem with pressure as nodal variable for the fluid domain and displacement for the plate. The time dependent equations are solved in each of the interacting domain using Newmark-b method. The effectiveness of the technique is demonstrated and the influences of surface wave, exciting frequency and flexibility of the plate on dynamic pressure are investigated.  相似文献   
13.
Yasser Kiani 《热应力杂志》2013,36(12):1495-1518
Based on the uncoupled thermoelasticity assumptions, axisymmetric thermally induced vibrations of a circular plate made of functionally graded materials (FGMs) are analyzed. Each thermomechanical property of the circular plate is assumed to be functions of temperature and thickness coordinate. Solution of the transient one-dimensional heat conduction equation with the arbitrary type of time-dependent boundary conditions is carried out employing the central finite difference method combined with the Crank–Nicolson time marching scheme. Afterwards, with the establishment of the associated Hamilton's principle and the accountancy of the von Kármán type of geometrical non-linearity, the motion equations are obtained with the aid of the conventional multi-term Ritz method. The solution of highly coupled non-linear motion equations is obtained utilizing a hybrid iterative Newton–Raphson–Newmark scheme. After validating the developed computer code, some parametric studies are accomplished to show the influences of various involved parameters. It is shown that temperature dependency, geometrical non-linearity, plate thickness, power law index, and the type of thermal in-plane and out-of-plane mechanical boundary conditions, all affect the temporal evolution of plate characteristics.  相似文献   
14.
In speech enhancement, having an accurate estimation of the power of the speech and noise signals forming the noisy observation is critical, as it can highly affect the performance of the enhancement algorithm. A method is introduced in which the distributions of the power of the speech and noise periodograms are modeled using the Gamma distribution to extract their shape parameters. These shape parameters are later used in the observed noisy speech to estimate the power when forming speech and noise periodograms. This method results in more accurate and faster power estimation with respect to the well‐known minimum statistics power estimation algorithm and together with the maximum a posteriori speech enhancement algorithm exhibits good speech enhancement performance.  相似文献   
15.
Grapefruit juice is consumed widely in today's health conscious world as a protector against cardiovascular diseases and cancers. It has however, been found to be an inhibitor of the intestinal cytochrome P – 450 3A4 system, which is responsible for the first pass metabolism of many drugs. The P – glycoprotein pump, found in the brush border of the intestinal wall which transports many of these cytochrome P – 450 3A4 substrates, has also been implicated to be inhibited by grapefruit juice. By inhibiting these enzyme systems, grapefruit juice alters the pharmacokinetics of a variety of medications, leading to elevation of their serum concentrations. Most notable are its effects on the calcium channel antagonist and the statin group of drugs. In the case of many drugs, the increased serum concentration has been found to be associated with increased frequency of dose dependent adverse effects. In this review, we have discussed the phytochemistry of grapefruit juice, the various drugs involved in the drug – grapefruit juice eraction with their mechanisms of action and have presented the clinical implications of these interactions.  相似文献   
16.
ZrP2O7 nanoparticles as an efficient catalyst have been used for the preparation of benzopyrano[2,3-b]pyridines from the four-component condensation reaction of salicylalde-hydes, thiols, and 2 equiv. of malononitrile under reflux conditions in ethanol in excellent yields and short reaction times.  相似文献   
17.
This paper presents a low voltage low noise open loop automatic amplitude control method for voltage-controlled oscillators (VCO’s). In this method a feedback mechanism keeps the VCO at its optimum amplitude over temperature and process variations and then the loop is broken to avoid noise injection form the control circuitry to the VCO. The loop does not add extra noise to the VCO. Based on the proposed method, a low voltage low noise LC-VCO was designed for a low phase noise application in TSMC 0.18 micron RFCMOS technology. Simulations show considerable improvement in the phase noise with the application of the proposed method.  相似文献   
18.
Multimedia Tools and Applications - Isolated hand sign language recognition from video is a challenging research area in computer vision. Some of the most important challenges in this area include...  相似文献   
19.
The Journal of Supercomputing - Graphics processing units (GPUs) are powerful in performing data-parallel applications. Such applications most often rely on the GPU’s memory hierarchy to...  相似文献   
20.
The Journal of Supercomputing - Agile software development (ASD) and software product line (SPL) have shown significant benefits for software engineering processes and practices. Although both...  相似文献   
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