Vertical Vibration of a Flexible Plate with Rigid Core on Saturated Ground

In this paper, the vertical vibration of a flexible plate with rigid core resting on a semi-infinite saturated soil is studied analytically. The behavior of the soil is assumed to follow Biot’s poroelastodynamic theory with compressible soil skeleton and pore water, and the response of the time-harmonic excited plate is governed by the classical thin-plate theory. By virtue of the Hankel transform technique, the fundamental solutions of the skeleton displacements, stresses, and pore pressure are derived, and a set of dual integral equations associated with the relaxed boundary and completely drained condition at the soil-foundation contact interface are also developed. These governing integral equations are further reduced to the standard Fredholm integral equations of the second kind and solved by numerical procedures. Comparison with existing solutions for a rigid permeable plate on saturated soil confirms the accuracy of the present solution. Selected numerical results are presented to show the influence of the permeability, the size of the rigid core, and the plate flexibility on the dynamic interaction between the elastic plate with rigid core and the underlying saturated soil.     

煤气吹扫时惰性气体抑爆用量的优选

运用惰性气体消防抑爆理论，采用数学积分法计算出吹扫煤气设施时抑爆所需最少惰性气体需要量．     

Two distinct protein-protein interactions between the NIT2 and NMR regulatory proteins are required to establish nitrogen metabolite repression in Neurospora crassa

Unrecognized and untreated depression occurs frequently in Alzheimer's disease (AD) patients, adding to the agony already experienced by patient and caregiver. The authors screened AD patients living with a family caregiver for depression. Twelve patients with confirmed depression were treated in an open-label study with antidepressant medication, with dosage adjustment by a psychiatrist at Weeks 2, 4, 8, and 16. Data collection occurred at baseline, Week 4, and Week 16. Depression decreased significantly (p < .01). Contrary to expectations, patient functional capacity declined (p = .045). Cognition remained unchanged (p > .05). Caregiver burden, caregiver depressive symptomatology, and quality of life of patient and caregiver remained unchanged (p > .05). The authors conclude that depression in AD can be detected if a collateral source, such as the caregiver, is available. The depression can and should be treated. More research is needed to determine the impact on patient functioning, caregiver burden, caregiver depressive symptomatology, and quality of life of patient and caregiver.     

Effect of aromatic diamine extenders on the morphology and property of RIM polyurethane–urea

An aromatic diamine, CMOMDA, was synthesized and used as a chain extender for reaction injection molding (RIM) polyurethane–urea. The morphology and properties of CMOMDA-, DETDA-, and MDA-extended poly(ether–urethane–urea)s (PEUUs) were measured by IR, DSC, DMS, SEM, and tensile testing apparatus. Well-matched values of C_h and X_ut,b/C_h were necessary for aromatic diamine-extended PEUU. DSC and SEM showed that the aggregation state of hard segments might undergo some changes with increasing hard-segment content. © 1994 John Wiley & Sons, Inc.     

In-laboratory removal of femoral sheath following protamine administration in patients having intracoronary stent implantation

Two hundred twenty-eight patients with successful coronary stent implantation were randomized either to protamine administration and femoral sheath removal (group I, n = 117) or no heparin neutralization and delayed sheath removal (group II, n = 111). The hospital stay after treatment was shorter in patients receiving protamine; therefore, protamine use for neutralizing circulating heparin may be safely administered immediately after stent implantation.     

Characterization of a cartilage-derived 66-kDa protein (RGD-CAP/beta ig-h3) that binds to collagen

Malignant human gliomas are the most common forms of primary tumors in the central nerve system. Due to their location and invasive nature, treatment so far has been mainly palliative. Thus, understanding the molecular detail of tumor transformation and progression is crucial for developing effective therapeutic strategy for this fetal tumor. Among the genetic alternations found in these tumors, p53 inactivation and PDGF/PDGFR activation represent the early events, and the loss of chromosome 10 and gene amplification and rearrangement of EGFR represent the late events. Studies with both glioma cell lines and primary tumor tissues have strongly suggested that TGF-alpha and EGFR function as an important autocrine loop in supporting proliferation of human glioma, especially in high grade glioma, since elevated TGF-alpha expression is also found in these high grade tumors. Furthermore, down regulation of the expression of TGF-alpha by antisense constructs has been shown to inhibit several types of human tumor cell growth including glioma. Other means of therapeutic approaches using this autocrine loop as a target also include the use of monoclonal antibodies and their cytotoxic conjugated. Considerable understanding of the EGFR-mediated signal transduction pathways has become available recently, which including GRB2/mSOS1 mediated MAP kinase activation; JAK/STATs pathway; PLC-gamma pathway. However, much work still needs to be done before a specific component of these pathways can be applied for effective control of tumor growth in the clinic.     

The effect of grain-size on the stress and velocity fields ahead of a crack in a material which deforms by Coble creep

The stress and velocity fields ahead of a grain-boundary crack in a material which deforms by Coble creep are investigated for a series of grain sizes using the numerical analysis technique established by Cocks [1–3]. The numerical results are compared with the linear viscous fields obtained by the boundary element method and the finite element method. It is demonstrated that a detailed knowledge of the micromechanical processes of material transport and deformation are required to determine the stress and displacement fields for the grains which immediately surround the crack tip. But the response of the surrounding material can be adequately described from a conventional linear viscous analysis of the problem.     

二阶A型Cooper变换的增强型

对二阶Ａ型Ｃｏｏｐｅｒ变换进行增强，放宽可用性条件，并证明了其正确性，最后举例说明其应用。     

纸张背衬不同衬底时的光反射率的研究

从理论上研究了纸张背衬不同衬底的光反射率，得出下列表达式：Ｒｂ＝Ｒｏ＋（Ｒ∞－Ｒｏ）×（１／Ｒ∞－Ｒｏ）／（１／Ｂ－Ｒｏ）（Ｂ为衬底的光反射率），该式简单实用且物理意义明确。利用上述公式，可将Ｔａｐｐｉ标准列出的Ｔａｐｐｉ不透明度Ｃ０．８９的换算公式简化，并可从理论上定性地讨论纸张不透明度与印刷透印性的关系。     

米塔尔钢铁集团的全球并购发展战略

概述了米塔尔的并购经过和并购特点,着重探讨了米塔尔的管理模式、人员情况、钢铁厂布局、生产经营、主要战略伙伴、研发机构及其生产、采购与销售策略。系统地分析了米塔尔在中国的发展,指出米塔尔在全球钢铁业整合中处于领先地位,米塔尔来中国投资看中的是中国的原料和市场,且运作步伐明显加快,会对中国钢铁企业构成很大的威胁。