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11.
BACKGROUND: Gastric sucrose permeability is a noninvasive marker that reliably increases in association with gastrointestinal injury due to use of nonsteroidal antiinflammatory drugs. Despite the effect of Helicobacter pylori infection on the gastric mucosa, in a previous study we were unable to demonstrate that H. pylori infection was associated with abnormal gastric sucrose permeability. Our goal in this study was to explore further whether H. pylori infection changed gastric permeability; therefore, we evaluated the effect of treatment of H. pylori infection on gastric permeability to sucrose and the relation of sucrose permeability to density of polymorphonuclear leukocytes. MATERIALS AND METHODS: Five hundred milliliters of a solution containing 100 gm of sucrose was ingested by the subject at bedtime. Overnight urine was collected and assayed for sucrose by high-performance liquid chromatography. Sucrose permeability was assessed both before and approximately 4 weeks after anti-H. pylori therapy. RESULTS: Seventeen asymptomatic H. pylori-infected volunteers participated; 8 were cured. Sucrose permeability was in the range commonly found in normal controls both before and after anti-H. pylori therapy (mean excretion, 76.3 mg; range, 13-171 mg). Gastric sucrose permeability correlated with the density of polymorphonulcear cell infiltration of the mucosa. Cure of the H. pylori infection was associated with a small but significant decrease in sucrose permeability (98.8 +/- 18 mg to 51.7 +/- 9.8 mg (p = .01). Sucrose permeability was greater in those with a high density of mucosal polymorphonuclear cells compared to those with lower scores (119.5 +/- 4 vs 71.4 +/- 13 for those with scores > or = 5 compared to scores < or = 4; p = .023). Failed therapy resulted in an increase in the mucosal density of polymorphonuclear infiltration and sucrose permeability (56.4 +/- 13 mg-99.7 +/- 19 mg pretreatment vs posttreatment, respectively; p = .031). CONCLUSION: H. pylori gastritis causes a small but measurable increase in gastric permeability to sucrose that may reflect epithelial transmigration of neutrophils.  相似文献   
12.
The purpose of this study is to examine the interface between financial strain, informal received economic support, informal anticipated financial support, and psychological distress in later life. Data provided by a large probability sample of older adults in the People's Republic of China reveal that the relationship between financial difficulty and psychological distress is stronger for older adults who receive more economic assistance. However, the results involving anticipated support are in the opposite direction. More specifically, the association between financial problems and psychological distress is lower for older adults who believe that others stand ready to help in the future should the need arise. A detailed theoretical rationale is developed to explain these results. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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14.
随着油田开发时间的延长,油水井井下套管的损坏将越来越严重,套管故障井将越来越多,为了恢复套损井生产,将套管损坏所造成的损失降到最低,在配套波纹管补贴,水动力补贴,爆炸补贴等专门修套技术的基础上,通过认真调查研究,又配套了操作方便简单,适用套管损坏类型广的自动力套管补贴加固技术,使各种套管变形,套管断错(错开没有位移或位移量不大时)、套管破裂,误射孔井段封堵,已射开水层封堵等修井作业的难度进一步降低,从而进一步提高了修复井综合开发经济效益。  相似文献   
15.
任翠枝 《山西建筑》2002,28(6):133-134
阐述了会计信息失真的表现形式及其危害性,从会计自身、内控制度、外部审计、道德观念、执法等方面分析了会计信息失真的原因,并从完善法规制度、实行会计委派制、健全会计监督体系、加强立法和执法力度、更新观念、提高素质等方面提出了治理会计信息失真的办法,从根本上杜绝会计信息失真的现象。  相似文献   
16.
中厚板轧制边部不均匀变形机理的探讨   总被引:1,自引:0,他引:1  
通过分析宽中厚板轧制过程中的边部不均匀变形,探讨了其影响因素及大宽度板“切边纵裂”的产生原因,提出了解决问题的具体办法。  相似文献   
17.
我国信息安全产品认证管理委员会的成立,标志着建立统一的信息安全认证认可体系的工作进入了实质性的实施阶段。有关高层主管纵论统一认证认可的意义、目标和希望,并勾勒出五年发展的大体框架。  相似文献   
18.
Carboxyl‐terminated butadiene‐acrylonitrile rubber (CTBN) has often been used to improve the toughness of cyanate ester (CE) resin while sacrificing modulus and thermostability. In this paper, the addition of the appropriate amount of epoxy resin (EP) to the CE/CTBN system is shown to not only increase the modulus and thermostability of the blend, but also improve the toughness. The values of impact strength showed a maximum for the CE/CTBN/EP 100/5/5 blend. The temperature of 10 % weight loss (T10) improves from 376 °C for CE/CTBN 100/5 to 407 °C for the CE/CTBN/EP 100/5/2.5 blend. It is proposed that addition of the appropriate amount of EP can decrease the mobility and increase the stability of CTBN via the reaction between the terminal carboxyl group of CTBN and the hydroxyl group of EP. But a very high EP concentration will decrease the crosslinking density of CE, consequently reducing the mechanical properties and thermostability of the blends. Copyright © 2004 Society of Chemical Industry  相似文献   
19.
A multi-channel continuous toxicity monitoring system developed in our laboratory, based on two-stage mini-bioreactors, was successfully implemented in the form of computer-based data acquisition. The multi-channel system consists of a series of a two-stage minibioreactor systems connected by a fiber optic probe to a luminometer, and uses genetically engineered bioluminescent bacteria for the detection of the potential toxicity from the soluble chemicals. This system can be stably and continuously operated due to the separation of the culture reactor from the test reactor and accomplish easy and long-term monitoring without system shut down by abrupt inflows of severe polluting chemicals. Four different recombinant bioluminescent bacteria were used in different channels so that the modes of the samples toxicities can be reasonably identified and evaluated based upon the response signature of each channel. The bioluminescent signatures were delivered from four channels by switching one at once, while the data is automatically logged to an IBM compatible computer. We also achieved the enhancement of the system through the manipulation of the dilution rate and the use of thermo-lux fusion strains. Finally, this system is now being implemented to a drinking water reservoir and river for remote sensing as an early warning system.  相似文献   
20.
Most algorithms on receiver autonomous integrity monitoring (RAIM) are under the assumption of a single-satellite fault, because there is an extremely small probability that significant simultaneous multiple-satellite faults may occur. However, after the implementation of the Galileo system in a few years, there will be more satellites in view for the user to utilise together with GPS satellites, and a combination of them will bring better performance for RAIM. On the other hand, with the help of wide area augmentation system and the use of dual-frequency operation, pseudo-range errors will be reduced greatly. Thus, tighter alert limits are required for RAIM, and formerly `small' errors should not be neglected. All of those factors make it necessary to consider simultaneous multiple-satellite faults. A detailed theoretical analysis of RAIM under the condition of two-satellite faults for both vertical and horizontal directions is presented. The characteristic/max slopes for every pair of satellites are then deduced in order to calculate the tighter vertical/horizontal protection level for RAIM  相似文献   
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