Sequential Interaction of Enamine with O,O -Dialkyldithiophosphoric Acid and Electrophilic Reagent

The adduct of O, O-dialkyldithiophosphoric acid and enamine reacts exothermically with an electrophilic reagent. In the case of sulfenyl bromide, the iminium salt reduced at the C-Br bond and bis(dialkoxythiophosphorylthio)-disulfide have been formed, experimentally evidencing the reaction of 2-halogenated ald- and ketimines with dithioic acid via the intermediate formation of enamine.     

Synthesis of (4-hydroxy-3,5-di-tert-butylphenyl)-chloromethanediphenylphosphine oxide and its reactions with aprotic nucleophilic reagents

Reaction of (4-hydroxy-3,5-di-tert-butylphenyl)chloromethanediphenylchlorophosphonium chloride with trimethyl orthoformate affords (4-hydroxy-3,5-di-tert-butylphenyl)chloromethanediphenylphosphine oxide. The latter undergoes dehydrochlorination under the action of trimethyl orthoformate and O-methyl diethylphosphinate, and with diphenylchloro- and triphenyl phosphines it gives the corresponding phosphonium salts.     

Phosphatidylinositol of the flowers of cotton plants of variety S-4880

Institute of Chemistry of Plant Substances, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 691–693, September–October, 1990.     

The Highly Regioselective Synthesis of Novel Imidazolidin-2-Ones via the Intramolecular Cyclization/Electrophilic Substitution of Urea Derivatives and the Evaluation of Their Anticancer Activity

A series of novel 4-(het)arylimidazoldin-2-ones were obtained by the acid-catalyzed reaction of (2,2-diethoxyethyl)ureas with aromatic and heterocyclic C-nucleophiles. The proposed approach to substituted imidazolidinones benefits from excellent regioselectivity, readily available starting materials and a simple procedure. The regioselectivity of the reaction was rationalized by quantum chemistry calculations and control experiments. The anti-cancer activity of the obtained compounds was tested in vitro.     

Synthesis and Properties of [4-(Diethylamino)phenyl]dichlorophosphine

Russian Journal of General Chemistry - [4-(Diethylamino)phenyl]dichlorophosphine synthesized for the first time has reacted with trialkyl orthoformate and ethylene oxide in the presence of ethyl...     

Synthesis of functionally substituted benzaldehydes

A new method of synthesis of functionally substituted benzaldehydes by catalytic debromometoxylation of dibromomethylarenes with benzaldehyde dimethyl acetal has been suggested. Anhydrous zinc chloride has been used as a catalyst. Being soft Lewis acid, it formed no strong complex with aldehyde group and other functional groups. The initial acetal has been readily recovered by the treatment of benzaldehyde isolated from the reaction mixture with trimethyl orthoformate.     

Approximate symmetries and solutions of the Kompaneets equation

Different approximations of the Kompaneets equation are studied using approximate symmetries, which allows consideration of the contributions of all terms of this equation previously neglected in the analysis of the limiting cases.