蛋白组学方法应用于人肺癌组织蛋白表达的研究

采用蛋白组学方法,利用4例中国肺癌患者的切除肺癌组织测定了磷癌(SQCLC)的蛋白表达 从双向电泳(2-DEgel)切下53个点,49个蛋白与数据库搜索结果吻合。在鉴定的24个蛋白中,17个蛋白有报道是与肺癌相关的蛋白其7个蛋白与人类其它癌症相关。所建立的蛋白组学方法能够用于建立一种基于组织的化验方法,发现肺癌患者组织中表达的蛋白标记物以用于癌症的分子学诊断。     

试论伪造货币罪的犯罪构成要件

伪造货币罪是最严重的货币犯罪，具体表现为仿照真货币制造假货币的行为。该行为的特点是“无中生有”、“仿真造假”。其仿制的对象既包括人民币，又包括外币，但不包括信用货币。伪造货币罪在主观方面应以“意图流通”为必备条件。根据刑法规定，该罪的犯罪主体仅限于自然人，不包括单位。     

关于中国近代历史进程基本线索的理论

近代史进程基本线索的理论,是中国马克思主义史学理论建设史上的一项重大收获。这一探讨历经曲折的过程。20世纪30年代,中国马克思主义学者论证了中国近代史主线是反帝反封建革命的正确观点;50年代对近代史分期进行了热烈的争鸣,认识更加深入,尤其是以范文澜为代表的学者提出同时应以资本主义的发展来考察近代社会进程的看法,具有前瞻性意义;进入新时期以后,在解放思想、实事求是路线指引下,学者们从新颖的视角进行思考和分析,更有许多新的创获,胡绳、李时岳、陈旭麓、刘大年的主张尤有代表性,集广大近代史研究者的共同努力,最终得出"两个基本问题"的科学认识。总结这一探索历程有深刻的意义,证明中国马克思主义史家坚持革命性与科学性二者相结合,坚持从掌握充分的史料来科学地分析问题,这同死搬教条的做法完全不可同日而语。这一理论问题最终圆满解决,是近代史领域坚持解放思想,坚持以唯物史观原理分析中国实际问题的逻辑依归。     

Inference for the measurement of poverty in the presence of a stochastic weighting variable

Empirical applications of poverty measurement often have to deal with a stochastic weighting variable such as household size. Within the framework of a bivariate distribution function defined over income and weight, I derive the limiting distributions of the decomposable poverty measures and of the ordinates of stochastic dominance curves. The poverty line is allowed to depend on the income distribution. It is shown how the results can be used to test hypotheses concerning changes in poverty. The inference procedures are briefly illustrated using Belgian data. An erratum to this article can be found at     

Randomized response techniques for complex survey designs

Singh et al. ([13]) pointed out that the Randomized response (RR) technique proposed by Moors ([9]) is not desirable because it fails to protect the confidentiality of the respondents and they provided two alternative strategies free from the above drawback but limited to SRSWOR sampling only. In this paper, generalization of one of the strategies is provided for complex survey designs, wider class of estimators and for quantitative characteristics. Relative efficiency of the modified strategy is tested through empirical investigations. An erratum to this article is available at .     

The Best and Worst Times of Life: Narratives and Assessments of Subjective Well-Being by Anamnestic Comparative Self Assessment (ACSA) in the Eastern Cape,South Africa

The Anamnestic Comparative Self Assessment (ACSA) measure of subjective well-being (SWB) aims to reduce the problems of cultural bias and relativity to external standards by allowing people to define the endpoints or ‘anchors’ of the measurement scale. In medical terminology anamnestic denotes ‘based on memory’. The ACSA uses subjects’ memories of the best and worst periods in their lives to define the anchors of the scale. They then assess their current quality of life relative to these personal anchors. The South African pilot study tested the match between self-assessment of SWB with ACSA and the conventional single-item measures of life satisfaction and happiness used in the South African Quality of Life Trends Study and analysed the narratives of the best and worst times of life. The quota sample of 46 consisted of 26 residents of Makana district in the Eastern Cape Province, South Africa, and 20 patients undergoing treatment in the local TB hospital. Mean SWB ratings with all three measures of life satisfaction, happiness and ACSA were between 5 and 6 on a 0–10-point scale. Ratings on all three scales were positively correlated. However, on ACSA the TB patients rated their current SWB 1.84 points lower than the community respondents, suggesting a greater sensitivity of this measure. It was observed that the starting points of the life stories produced by respondents to define the anchor periods for ACSA were related to their current assessment of SWB. A typology was developed that combined the starting point of the life stories with current SWB. The majority of community respondents matched the ‘Achiever’ type who scored positively on ACSA (i.e., above the mid-point of the scale) and whose life stories started with the worst period of their lives and proceeded to the best period. The TB patients were the only respondents to represent the ‘Survivor’ type whose morale had recovered after misfortune in life. ‘Survivors’ started their narratives with the best period in their lives, then moved to the worst (often health-related) one, and gave positive ACSA ratings. Based on the qualitative analysis of narratives, it is concluded that ACSA is a sensitive measurement instrument and therefore particularly useful for monitoring the effects of treatments and social interventions in longitudinal studies. However, further research is required to verify its cross-cultural validity.

Does parents’ valuation of children’s health mimic their valuation of own health?

A single latent variable model of health status and therapeutic health care utilization is estimated for parents and own children of 6,557 US households. The equation system that identifies latent health status simultaneously determines a number of indicators of general health, including presence of morbidity symptoms, mobility limitations, medication needs, and utilization of therapeutic health care services. The main goal of the paper was to obtain an unbiased estimate of parents’ marginal substitution rate between own and child health. Results indicate that parents’ valuation of their children’s health exceeds their valuation of own health by almost twofold on average.

后现代国际私法理论探微

后现代国际私法理论是当代国际私法学的一种新兴理论 ,本文从其哲学渊源———后现代主义出发 ,评析其基本主张及其对当代国际私法发展的影响 ,并结合中国的具体理论与实践 ,探讨中国国际私法学对该理论的应对模式。