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91.
Value of the D-dimer test in diagnosing deep vein thrombosis in rehabilitation inpatients 总被引:3,自引:0,他引:3
Akman MN Cetin N Bayramoglu M Isiklar I Kilinc S 《Archives of physical medicine and rehabilitation》2004,85(7):1091-1094
OBJECTIVE: To assess the utility of the D-dimer test-a widely available, less costly, and less time-consuming test than others used to diagnose or exclude deep vein thrombosis (DVT) and pulmonary embolism. DESIGN: Blind comparison. SETTING: An inpatient rehabilitation facility in Turkey. PARTICIPANTS: Sixty-eight consecutive inpatients being rehabilitated after stroke, spinal cord injury, hip arthroplasty, or traumatic brain injury. INTERVENTIONS: A latex D-dimer assay was performed on each patient at admission and then weekly throughout the hospital stay. Color Doppler ultrasonography of the lower limbs was also done for each patient at admission and was repeated when indicated by clinical signs and symptoms of DVT or by elevated D-dimer levels.Main outcome measures Patients' clinical findings, D-dimer test results, and ultrasonography results were recorded. Sensitivity, specificity, and positive and negative predictive values were calculated for the D-dimer test, each clinical finding, and combinations of D-dimer results and clinical findings in relation to DVT diagnosis. RESULTS: The sensitivity and negative predictive value of the D-dimer test were high, at 95.2% and 96.2%, respectively. The specificity and positive predictive value were low, at 55.3% and 48.7%, respectively. No single clinical finding was reliably diagnostic for DVT. CONCLUSIONS: The D-dimer assay is a reliable method for ruling out DVT. In the rehabilitation setting, it can be used as a routine screening test or to assess cases of suspected DVT. D-dimer testing may reduce the need for sophisticated, time-consuming, and expensive diagnostic workup of rehabilitation inpatients, a group that is at increased risk for DVT. 相似文献
92.
Effects of alendronate sodium therapy on carotid intima media thickness in postmenopausal women with osteoporosis 总被引:3,自引:0,他引:3
Osteoporosis and cardiovascular disease are major health problems that lead to morbidity and mortality. Bisphosphonates are
among the drugs used most frequently worldwide to treat osteoporosis, especially in older women. B-mode ultrasonography has
recently become a valuable tool for early diagnosis of atherosclerotic disease because of its ability to measure carotid artery
intima media thickness (CIMT). The purpose of the present study was to investigate whether alendronate sodium therapy has
an effect on CIMT in postmenopausal women with osteoporosis. A total of 71 postmenopausal women with osteoporosis were evaluated
before and after they began taking alendronate sodium; follow-up was provided for an average of 13±2 mo. Osteoporosis was
diagnosed with the use of dual-energy x-ray absorptiometry, and therapy with alendronate sodium was begun at a dose of 70
mg/wk. For CIMT, B-mode ultrasonography was performed on the right and left middle and distal main carotid arteries. Before
alendronate sodium therapy was initiated, the average CIMT value was 0.734±0.121 mm; after therapy, the average CIMT was 0.712±0.111
mm. This difference was not confirmed to be statistically significant. Treatment of osteoporosis does not seem to have an
effect on CIMT, which is an early marker of atherosclerosis. 相似文献
93.
Ahmet Yilmaz Coban Ismail Ceyhan Meltem Uzun Gonca Erkose Genc Can Bicmen Nuri Ozkutuk Suheyla Surucuoglu Ozlem Yanar Gonul Aslan Nurbanu Kurnaz Yeliz Tanriverdi Cayci 《Indian journal of medical microbiology》2022,40(1):127-131
PurposeThe aim of this multicenter study is to evaluate AYC.2.2 agar for the isolation of mycobacteria from clinical samples.MethodsTotally 5559 media were tested in 7 centers. AYC.2.2 agar media for the study were prepared by C1 and sent to other centers under appropriate conditions. Other media except AYC.2.2 agar were purchased commercially.The media were subjected to routine laboratory operations in the center where they were sent. After the samples received for routine processing (in all centers, samples were processed with the same method (NALC-NaOH)), they were cultivated on routine media and AYC.2.2 agar afterward.ResultsC1: Average growth time was determined as 12.74±3.74 days with MGIT 960 system; 24.42±4.75 days with LJ and 24.37±4.96 days with AYC.2.2 agar. C2: Average growth time was determined as 18.25±9.32 days with TK-Medium, 28.73±7.44 days with LJ, and 31.72±6.35 days with AYC.2.2 agar. C3: Average growth time was determined as 20.48±7.24 days with Ogawa medium, 20.74±7.12 days with LJ, and 20.26±7.43 days with AYC.2.2 agar. C4: Average growth time was determined as 15.27±6.37 days with MGIT 960 system, 22.14±9.1 days with LJ, and 22±8.45 days with AYC.2.2 agar. C5: Average growth time was determined as 13±4.24 days with MGIT 960 system, 32.16±6.23 days with LJ, and 33±5.73 days with AYC.2.2 agar. C6: Average growth time was determined as 9±3.11 days with MGIT 960 system, 18.68±5.32 days with LJ, and 18.34±4.63 days AYC.2.2 agar. C7: Average growth time was determined as 14.74±7.65 with MGIT 960 system, 26.01±8.21 days with LJ, and 26.24±7.88 days with AYC.2.2 agar.ConclusionsIn conclusion, similar results were obtained with LJ and Ogawa media and AYC.2.2 agar. Furthermore, more studies should be conducted for isolation of M. tuberculosis and performing antibiotic susceptibility tests using AYC.2.2 agar before it can be used as a routine media in the laboratories. 相似文献
94.
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96.
Huseyin Demirors Esra Circi Rahmi Can Akgun Nefise Cagla Tarhan Nuri Cetin Sercan Akpinar Ismail Cengiz Tuncay 《International orthopaedics》2010,34(4):531-536
The aim of this study was to investigate the correlation of tendon integrity following open cuff repairs with functional and
isokinetic strength measurements. Twenty-six shoulders of 25 patients were included in this study. At the final follow-up,
14 repairs (53.8%) were intact and 12 repairs (46.2%) had failed on magnetic resonance imaging (MRI). Mean UCLA score at latest
follow-up was 28.5 and mean Constant score was 80.3. Constant scores were found to be significantly low for the failed group.
Age was found to be significantly related to failed repair. Fatty infiltration stage in the failed repair group was significantly
high, and a strong positive correlation for both groups existed pre and postoperatively. When both groups were compared, the
failed group was found to have significantly low measurements at extension and internal rotation. Despite high failure rates,
functional results were satisfactory. Increased age and fatty infiltration stage decrease success. 相似文献
97.
98.
Mahmut Acikel MD Nuri Kose MD Alpay Aribas MD Hasan Kaynar MD Serdar Sevimli MD Yekta Gurlertop MD M.Kemal Erol MD 《Clinical cardiology》2010,33(8):E13-E18
Background
Pulmonary hypertension (PH) caused by chronic obstructive lung disease (COLD) essentially involves the right heart. Also left ventricular (LV) systolic and diastolic functions may be affected.Objectives
The aim of this study was to investigate the effect of on LV diastolic function in patients with COLD.Methods
A total of 47 patients with COLD and 20 controls were included in this study. All patients underwent Doppler echocardiography, tissue Doppler imaging examinations and right cardiac catheterization. The patients were divided into 2 subgroups according to mean pulmonary arterial pressure (mPAP): patients without PH (group1, n = 25) and with PH (group 2, n = 22). The following measurements were taken: peak velocity of early diastolic filling (E), peak late filling with atrial contraction (A), E/A ratio, deceleration time (DT) of E, isovolumic relaxation time (IVRT), early (Em) and late (Am) diastolic mitral lateral annulus velocity.Results
Mitral E/A < 1 and Em < 8 cm/sec were higher in group 2 than in group 1 and the control group. There were significant correlations between mPAP and both mitral E/A (r:? 0.60) and Em (r:? 0.45). In multivariate model, mPAP was not found to be significant on mitral E/A ratio < 1, but there was a significant effect on mitral Em < 8 cm/sec (odds ratio [OR]:1.14, P < 0.05).Conclusion
This study shows that LV diastolic dysfunction in COLD is closely correlated to PH levels. Although increased mPAP may affect the mitral E/A ratio, it seems to have no effect on mitral E/A < 1, whereas it has an independent effect on Em < 8 cm/sec. Copyright © 2010 Wiley Periodicals, Inc.99.
Bezer M Saygi B Aydin N Kucukdurmaz F Ekinci G Guven O 《Archives of orthopaedic and trauma surgery》2009,129(8):1017-1024
Background The combination of the reconstruction of the coracoclavicular ligaments with the resection arthroplasty of the distal end
of the clavicle is a commonly used technique in acromioclavicular separations.
Hypothesis The purpose of the current study was to quantify the reduction parameters using 3-D CT and to analyze their effects on clinical
outcomes.
Study design Case series.
Methods The patients with chronic symptoms after acromioclavicular dislocation (type III) were treated with reconstruction of the
coracoclavicular ligaments. The average follow-up was 69.5 months. The patient group consisted of 21 men and 8 women. The
initial treatment at the time of injury was nonoperative in 26 of 29 patients. CT was used to document anteroposterior (APD),
craniocaudal (CCD) and mediolateral (MLD) acromioclavicular reduction parameters. Constant Shoulder scoring system was used.
Results The mean preoperative Constant score was 56.62 ± 18.63 points while the postoperative score was 89.93 ± 10.79 points. The
mean APD was 9.2 mm, the mean CCD was 1.1 mm and the mean MLD was 8.4 mm. There was no correlation between the APD, MLD and
the Constant Scores. However, an inverse correlation between the CCD and the postoperative Constant Scores was found.
Conclusions CCD plays an important role on the postoperative function. If the CCD is larger, the Constant score is lower.
Clinical relevance The reduction loss is a distinctive parameter of the functional outcome, even when the reconstructed coracoclavicular ligament
is intact. Secure fixation may be achieved with techniques preserving CCD. 相似文献
100.
This study aims to identify the effect of stiffness on renal artery Doppler sonograms by using a curve fitting approach. The
study includes 20 patients with suspected renovascular hypertension. Each patient underwent recordings during renal artery
examinations before and after administration of Captopril 25 mg (Kapril tablet, MN Pharmaceuticals, Istanbul, Turkey). Doppler
signals were analyzed with short time Fourier transformation, followed by curve fitting to sonograms using Savitzky–Golay
method. Doppler parameters obtained from pre- and post-Captopril curve-fitted sonograms were statistically compared with “Paired-Samples
t-Test”. Captopril administration resulted in a significant decrease in the mean frequency and a significant increase in Pulsatility
Index of the periods. No significant difference was detected between maximum systolic and minimum diastolic frequencies, Resistivity
Index, and the Acceleration Index. The computational approach in this study appears to be promising. 相似文献