乌鲁木齐机场GNSS地基增强I类精密进近研究与实现

2019 年民航局发布《中国民航北斗卫星导航系统应用实施路线图》，推动北斗卫星导航系统民航应用。为研究融合北斗卫星的地基增强系统(GBAS)新技术在乌鲁木齐“智慧机场”的应用，对 GBAS 的发展研究现状进行了说明，论证了乌鲁木齐机场 GBAS 建设的必要性和可行性，在此基础上完成了 GBAS 技术方案，满足 GNSS 地基增强 I 类精密进近的技术需求，为后续乌鲁木齐机场 GBAS 的相关建设提供了重要的理论依据。     

机载远程探测用高能量双波长激光器研究

激光器是机载远程光电探测系统的重要组成部分,其性能直接决定系统应用效果.首先从激光测距方程出发,分析不同探测体制以及双波长探测需求;然后针对半导体泵浦固体激光器进行研究,并对不同双波长实现方式进行了分析;最后通过试验验证,实现了高能量双波长激光输出.试验结果表明:通过主动电光调Q技术和LD侧面泵浦共腔谐振技术,可以实现高重频窄脉宽1.064μm和1.57μm双波长激光输出.     

影响荔枝酒发酵过程中挥发酸的因素

挥发酸的控制是荔枝酒的生产过程中的重要技术瓶颈,发酵过程易造成荔枝果酒挥     

装配式建筑电气设计关键技术分析

介绍装配式建筑电气设计中的管线分离SI体系、模块化机电设计、集成机电部品、装配式建筑防雷接地系统等关键技术,并进行简要分析.     

建筑工业化产品的系统论与装配式住宅设计

从建筑工业化产品的系统论出发,聚焦建筑设计方法与策略,结合装配式建筑系统集成特征,提出装配式建筑设计七个方面的设计策略,并分析其思路和相关手法.     

The effect of alkali metal oxide on the properties of borosilicate fireproof glass: Structure,thermal properties,viscosity, chemical stability

The purpose of the current work was to research the effect of alkali metal oxide on the structure, thermal properties, viscosity and chemical stability in the glass system (R₂O–CaO–B₂O₃–SiO₂) systematically. Because the glass would emulsify when Li₂O was added to the glass batch, this article did not discuss Li₂O. The results showed that when the amount of Na₂O was less than 4 mol.%, there was a higher interconnectivity of borate and silicate sub-networks in glass, as more mixed Si–O–B bonds were present in glass. The glass samples exhibited excellent thermal properties and chemical stabilities. As the amount of Na₂O exceeded 4 mol.%, the interconnectivity of borate and silicate sub-networks was weakened. The thermal properties and chemical stabilities of the glass samples were reduced. The connectivity of the silicate sub-network was weakened slightly as the Na/K ratio varied, and the coefficient of thermal expansion (CTE) of the glass samples gradually increased, and the resistance to thermal shock (RTS) value gradually decreased. Moreover, the viscosity of the glass samples decreased with the ratio of Na/Si and Na/K increased.     

高稳高效海上风电安装平台关键制造技术研究

海上风电作为可再生清洁能源之一,受到世界各国的高度重视与大力发展。我国将海上风电提升至解决能源危机、减缓气候变化、调整能源结构的国家战略高度,到2030年我国单位国内生产总值二氧化碳排放将比2005年下降65%以上,非化石能源占一次能源消费比重将达到25%左右。安装平台不足将是我国海上风电场无法如期建成投产的主要障碍。对自升自航式海上风电安装平台系列高端装备及其设计制造的三大技术难题——腿站立作业易“失稳”、大平台大跨距大倾覆力矩自升易“失控”、高空吊装巨型叶片逾百螺栓精准定位易“失准”,以及焊缝缺陷修复和局部裂纹损伤的激光锻造修复再制造进行了介绍,研制的具有不同规格的系列装备在中国、英国、丹麦、德国等国家的著名海上风电场建设应用情况良好。     

凌庄子水厂保水堰流量系数试验

凌庄子水厂蓄水池进水口处有一保水堰,为非标准薄壁堰,不能使用已有堰流公式对其过流量进行准确计算。为了得出较为精确的过流流量,按照重力相似准则制作几何比尺为1∶5的模型进行试验研究。在已有自由出流公式的基础上,对自由出流流量系数进行修正并对淹没情况下流量变化过程进行研究。对该非标准堰自由出流流量系数的实测值与经验值进行分析比较,发现堰板槽降低了实际自由出流过流能力。淹没出流的流量系数主要与下游尾水位有关,试验中形成的淹没式堰流受实际堰型尺寸影响,下游尾水位和堰上水位近似相等,不完全适用已有淹没出流流量公式,通过试验给出了修正淹没系数随h/p的变化关系。结果表明利用堰前、堰后水位初步计算过流流量是可行的,可为该工程提供参考,也可为实际工程中非标准矩形堰的流量计算提供思路。     

基于网络的决策支持系统在水资源管理中的应用

综述了决策支持系统(DSS)与基于网络的决策支持系统(Web-based DSS)在水资源管理中的应用概况,通过对二者进行比较,指出Web-based DSS具有便于系统更新维护、降低用户使用门槛、扩展用户沟通渠道等优势。对Web-based DSS涉及的基础应用开发、多源信息采集与集成、多模块并行耦合、决策效果评估等关键技术进行了分析,探讨了Web-based DSS在多源异构大数据环境下面临的问题与挑战。     

AQP3 Increases Intercellular Cohesion in NSCLC A549 Cell Spheroids through Exploratory Cell Protrusions

Tumor cell aggregation is critical for cell survival following the loss of extracellular matrix attachment and dissemination. However, the underlying mechanotransduction of clustering solitary tumor cells is poorly understood, especially in non-small cell lung cancers (NSCLC). Here, we examined whether cell surface protrusions played an important role in facilitating the physical contact between floating cells detached from a substrate. We employed poly-2-hydroxyethyl methacrylate-based 3D culture methods to mimic in vivo tumor cell cluster formation. The suprastructural analysis of human NSCLC A549 cell spheroids showed that finger-like protrusions clung together via the actin cytoskeleton. Time-lapse holotomography demonstrated that the finger-like protrusions of free-floating cells in 3D culture displayed exploratory coalescence. Global gene expression analysis demonstrated that the genes in the organic hydroxyl transport were particularly enriched in the A549 cell spheroids. Particularly, the knockdown of the water channel aquaporin 3 gene (AQP3) impaired multicellular aggregate formation in 3D culture through the rearrangement of the actomyosin cytoskeleton. Moreover, the cells with reduced levels of AQP3 decreased their transmigration. Overall, these data indicate that cell detachment-upregulated AQP3 contributes to cell surface protrusions through actomyosin cytoskeleton remodeling, causing the aggressive aggregation of free-floating cells dependent on the property of the substratum and collective metastasis.