乌拉地尔治疗高血压急症的疗效观察

目的:观察静脉注射剂乌拉地尔对高血压急症的疗效。方法:选择89例高血压急症女性患者,静脉使用乌拉地尔治疗,并记录用药后5min、0.5h、1h、2h、4h、6h、12h及24h血压及心率。结果:89例患者在用药后5min内血压明显下降,收缩压由(218.2±14.7)mmHg降至(201±13.3)mmHg(1mmHg=0.133kPa),P<0.01,舒张压由(119.3±6.7)mmHg降至(109.7±5.4)mmHg,P<0.01。显效率100%。仅有2例出现头晕,但可耐受。结论:静脉使用乌拉地尔降低血压起效迅速、疗效肯定、使用安全、简单、副作用轻微,可作为高血压急症的首选药。     

乌拉地尔治疗老年高血压急症

目的 :观察乌拉地尔治疗老年高血压急症的降压作用。方法 :对 47例高血压急症患者给予乌拉地尔 12 .5～ 2 5mg加生理盐水 10ml稀释后 3～ 5分钟内静注 ,必要时 10分钟后再重复注射 1次 ,然后将 5 0mg乌拉地尔加入 2 5 0ml液体中以 0 .1～ 0 .4mg/min速度静滴 ,观察用药后 5min、15min、30min、1h、2 4h血压、心率变化 ,同时记录用药量、临床表现和不良反应。结果 :给药后 5min血压开始下降 (P <0 .0 5 ) ,至 6 0min降至理想血压 (P <0 .0 1) ,总有效率 10 0 %。心率随血压下降而减慢 (P <0 .0 5 )。结论 :乌拉地尔降压作用迅速而平稳 ,剂量容易掌握 ,不良反应少 ,可以作为老年高血压急症的首选降压药     

乌拉地尔静脉注射治疗高血压急症的疗效观察

目的：观察乌拉地尔静脉注射治疗高血压急症的疗效及安全性。方法：22例高血压急症患者静脉注射乌拉地尔25mg(5min内）、随后以100－200μg/min静滴维持，观察用药前后血压、心率变化。结果：用药后5min血压明显下降，30min达到高峰并维持稳定，有效率100％，心率无明显变化。结论：乌拉地尔治疗高血压急症降压效果确切，副作用少，不影响心率。     

乌拉地尔治疗高血压急症的疗效观察

目的观察静脉注射剂乌拉地尔对高血压急症的疗效.方法选择89例高血压急症女性患者,静脉使用乌拉地尔治疗,并记录用药后5min、0.5h、1h、2h、4h、6h、12h及24h血压及心率.结果89例患者在用药后5min内血压明显下降,收缩压由(218.2±14.7)mmHg降至(201±13.3)mmHg(1mmHg=0.133kPa),P＜0.01,舒张压由(119.3±6.7)mmHg降至(109.7±5.4)mmHg,P＜0.01.显效率100%.仅有2例出现头晕,但可耐受.结论静脉使用乌拉地尔降低血压起效迅速、疗效肯定、使用安全、简单、副作用轻微,可作为高血压急症的首选药.     

盐酸乌拉地尔治疗高血压急症40例临床疗效及安全性的观察

目的:评估盐酸乌拉地尔治疗高血压急症的临床疗效及安全性。方法:选取本院2010年12月1日～2011年11月31日1年内急诊及ICU重症高血压患者40例,其中男性26例,女性14例,给予盐酸乌拉地尔静滴或静推等治疗,观察用药后15、30、60、120 min的血压,心率变化及不良反应。结果:与用药前比较,用药后15、30、60、120 min的收缩压,舒张压明显下降,差异有统计学意义(P<0.05)。用药前后,心率略减慢,有差异但无统计学意义。其中有3例有头晕及恶心等不良反应,均能耐受。治疗后27例显效,12例有效,1例无效。结论:乌拉地尔治疗高血压急症疗效快,显效率高,不良反应轻微,可作为高血压急症的首选用药。     

乌拉地尔和硝普钠治疗高血压急症的疗效观察

目的观察经微量泵静脉注射乌拉地尔和硝普钠治疗高血压急症的疗效。方法高血压急症84例随机分为乌拉地尔治疗组(n=43)和硝普钠对照组(n=41),两组经微量注射泵持续给药,盐酸乌拉地尔组:盐酸乌拉地尔100mg稀释于50ml生理盐水中微泵静脉注射,据血压调整速度。硝普钠组50mg加入5%葡萄糖50ml,0.25μg/kg·min开始,5min监测血压1次,据血压调整给药剂量;记录血压、心率、心电图等资料。结果盐酸乌拉地尔组43例(97.7%)显效,30min内收缩压从治疗前的(203.3±15.5)mmHg降至(167.2±16.4)mmHg(P<0.05),舒张压也显著下降[(124.6±13.9)mmHg∶(103.0±15.8)mmHg,P<0.05];两组显效率有显著差异(97.7%∶82.9%,P<0.05)。结论静脉应用盐酸乌拉地尔降血压疗效肯定,使用安全,副作用少,可作为高血压急症的首选药物。     

高血压患者行腹部急诊手术的麻醉处理

目的:探讨联合应用盐酸乌拉地尔和硝酸甘油治疗中重度高血压患者行上腹部全身麻醉急诊手术时控制血压的疗效和安全性。方法:ASA2~3级高血压患者25例,于诱导插管前及术毕拔管前,静注盐酸乌拉地尔,分别观察静注后至20 min时收缩压(SBP)、舒张压(DBP)、心率(HR)的变化。术中观察泵注硝酸甘油至60 min及停药后至30 min,SBP、DBP、HR的变化。结果:诱导插管前静注药物后2 min,SBP、DBP即显著下降,HR无明显改变,术毕拔管前静注药物后,SBP、DBP,显著下降,且维持至20 min。术中泵注硝酸甘油时,SBP、DBP显著下降,且维持至停药后30 min,而HR无显著改变。结论:联合应用乌拉地尔及硝酸甘油能有效控制血压,维持全麻诱导、拔管时血压、心率的平稳,维持术中血流动力学的稳定。     

乌拉地尔治疗高血压急症20例的疗效观察

1998年以来,我们用乌拉地尔治疗高血压急症20例,取得了较显著的降压效果,现报道如下。1　资料与方法11　一般资料　本组男性12例,女性8例。年龄45～72岁。均为高血压急症患者,其中高血压脑病15例,高血压危象4例,高血压性心脏病并急性左心衰1例。12　用药方法　乌拉地尔125～25ｍｇ用5%葡萄糖溶液10ｍＬ稀释后静注(3～5ｍｉｎ),必要时20ｍｉｎ后可重复1次。血压降至满意水平后将乌拉地尔50ｍｇ加入250ｍＬ葡萄糖液中以(01～02)ｍｇ/ｍｉｎ维持静滴,视患者血压水平调整输液速度,一般4～6ｈ后可用口服药物维持治疗。并同时根据高血压所致器官受…     

静脉应用乌拉地尔对老年高血压急症36例临床观察

目的观察静脉应用乌拉地尔对老年高血压急症的临床疗效.方法对36例老年高血压急症患者,采用乌拉地尔首次剂量25mg加入生理盐水20ml中静脉推注(时间＞15min),随后用100mg加入5%葡萄糖液或生理盐水250ml缓慢静滴,以10-30mg/h速度,根据血压调控滴速,连续心电监护,于用药前和用药后5、10、15、30 min及1、2、4、6h记录血压、心率及观察其不良反应.结果用药后5min时显效77.7%(28/36),30min时有效16.6%(6/36),总有效率94.4%.用药前后对比血压差异显著(P＜0.01),心率差异无显著变化(P＞0.05),未见明显不良反应.结论静脉应用乌拉地尔治疗老年高血压急症,起效快、降压平稳安全、疗效好,可作为急诊救治老年高血压急症的首选药物之一.     

乌拉地尔治疗老年人高血压急症首次剂量的选择

目的　观察乌拉地尔治疗老年人高血压急症的降压效果以及首次剂量的选择。方法　将 15 5例高血压急症患者随机分为两组 :A组 74例 ,将盐酸乌拉地尔首剂 2 5 0mg加入 0 9%氯化钠溶液 10ml中稀释后于 3～ 5min内静注。B组 81例 ,将乌拉地尔首剂 12 5mg加入 0 9%氯化钠溶液 10ml中稀释后于 3～ 5min内静注。观察两组患者用药前、用药后 30min血压、心率 (HR)的变化情况 ,同时记录用药量、临床表现和不良反应。结果　首次静脉注射2 5 0mg和 12 5mg的乌拉地尔疗效相当 ,而首次静脉注射 12 5mg组低血压发生率明显低于 2 5 0mg组 ,两组降压后心率降低不明显。结论　乌拉地尔降压作用迅速而平稳 ,不良反应少 ,常作为老年高血压急症的首选降压药 ,治疗的首次剂量以 12 5mg为宜。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.