彩色多普勒超声对脑梗死患者颈动脉粥样硬化斑块的临床评价

目的 探讨脑梗死患者颈动脉粥样硬化病变特点,彩色多普勒超声对颈动脉粥样硬化斑块的临床诊断价值.方法 应用EUB-6500彩超仪器对36例脑梗死患者(脑梗死组)和48例正常人(对照组)进行颈动脉检查.结果 脑梗死组颈动脉粥样硬化斑块检出率显著高于对照组(P＜0.01),脑梗死组软斑比例显著大于对照组(P＜0.01 );脑梗死组左颈总动脉收缩期峰值流速(SPV)、舒张末期(EDV)较对照组明显减低(P＜0.05),阻力指数(RI)比对照组增高(P＜0.05).结论 脑梗死的发生、发展与颈动脉粥样硬化病变密切相关;彩色多普勒超声检查可为脑梗死预防与治疗提供参考.     

彩色多普勒超声对颈动脉粥样硬化与脑梗塞相关性的研究应用

目的 通过彩色多普勒超声对颈动脉粥样硬化的检测,评价颈动脉粥样硬化与脑梗塞的关系.方法 采用高频彩色多普勒超声检查55例脑梗塞患者的颈动脉,测量其内径、内-中膜厚度(IMT)、血流速度等参数,观察斑块的有无及形成情况,并以50例健康者作为对照组.结果 55例脑梗塞患者中,颈动脉粥样硬化斑块形成、管腔狭窄等血管异常者45例,检出率占87%;对照组中有IMT增厚和斑块形成者9例,占18%,二者比较有显著差异(P＜0.01).结论 颈动脉粥样硬化与脑梗塞密切相关,颈动脉粥样硬化斑块是引起脑梗塞的重要原因.高分辨力彩色多普勒超声诊断技术能早期发现颈动脉粥样硬化,有效判断狭窄程度,并对斑块进行分型,有利于临床选择治疗方案及估计预后,预防脑梗塞,提高病变治愈率.     

颈动脉粥样硬化预测冠心病的临床价值

目的 探讨颈动脉粥样硬化预测冠心病(CHD)的临床价值.方法 采用高分辨率超声测定86例CHD和46例正常对照者颈动脉内中膜厚度和斑块积分.结果 CHD组斑块发生率明显高于对照组(77.9%vs17.4%,P＜0.01).CHD多支病变组平均颈动脉内中膜厚度(mIMTc)较单支病变组明显增厚[(0.99+0.17)mm vs(0.85±0.15)mm,P＜0.01],其斑块积分也较单支病变组高[(2.68±1.82)vs(1.60±1.27),P＜0.05].以mIMTc≥0.85 mm预测CHD的有无,其敏感性为72.1%,特异性为76.1%,总符合率73.5%(97/132).结论 高频超声能准确测量颈动脉内中膜厚度及斑块情况,颈动脉粥样硬化与冠状动脉粥样硬化密切相关,颈动脉粥样硬化程度可间接反映冠状动脉病变的程度.     

脑梗塞与颈动脉粥样硬化斑块间的关系

目的 探讨颈动脉粥样硬化斑块好发部位、狭窄程度及与脑梗塞的关系.方法 对80例脑梗塞患者及正常对照组90例进行颈动脉超声检测,了解有无斑块形成及狭窄程度.结果 80例脑梗塞患者中发现颈动脉内存在不同程度的颈动脉粥样硬化斑块有72例且好发于颈动脉分叉部.正常对照组90例发现颈动脉粥样硬化25例,梗塞组与对照组比较,有显著差异（P＜0.01）.结论 颈动脉粥样硬化与脑梗塞密切相关.     

彩色多普勒超声对颈动脉粥样斑块与脑梗死的诊断价值

目的：探讨彩色多普勒超声对颈动脉粥样斑块与脑梗死的诊断价值。方法选择2011年10月～2013年10月长沙市第一医院收治的70例脑梗死患者和70例健康体检者,分别作为观察组和对照组。应用彩色多普勒超声仪对2组颈动脉内中膜厚度（IMT）、斑块类型、斑块形态,进行检测和比较。结果与对照组相比,观察组颈动脉粥样硬化斑块形成率显著升高（77.1% vs 24.3%）,并且斑块类型多为不稳定的软斑;与对照组相比,观察组颈动脉IMT明显增大（1.3±0.3） vs （0.7±0.2）,差异有统计学意义（P＜0.05）。结论颈动脉粥样斑块与脑梗死密切相关,颈动脉彩色多普勒超声检查能够明确脑梗死患者颈动脉粥样硬化斑块特征,具有较高的临床诊断价值。     

彩色多普勒超声在脑梗死患者颈动脉粥样硬化诊断中的应用

目的：探讨彩色多普勒超声对脑梗死患者颈动脉粥样硬化的诊断价值.方法：对123例脑梗死患者及90名正常人的颈动脉内中膜厚度及斑块形成进行对比分析.结果：脑梗死患者颈动脉粥样硬化斑块形成检出率63.4％,单纯内膜增厚检出率21.9％;55岁以上组颈动脉斑块检出率明显高于55岁以下组（P＜0.05）.正常人颈动脉粥样硬化斑块形成检出率6.7％;单纯内膜增厚检出率11.1％;脑梗死组颈动脉粥样硬化斑块形成检出率高于对照组（P＜0.01）;脑梗死患者患有高血压病的颈动脉粥样硬化斑块检出率72.6％,患糖尿病的颈动脉粥样硬化斑块检出率60.0％,同时患有高血压及糖尿病颈动脉粥样硬化斑块检出率84.4％,明显高于无高血压及糖尿病患者（P＜0.01）.结论：彩色多普勒超声检查可早期发现脑梗死患者是否有颈动脉粥样硬化,以55岁以前为关键期,是一种无创、有价值的实用方法.     

颈动脉实时三维超声在冠心病危险评估中的应用价值

目的:探讨实时三维超声技术于颈动脉粥样硬化评估及间接对冠心病的病变程度的评估中的应用价值。方法:将100例疑似冠心病患者分为冠心病组和对照组(非冠心病组),均行冠脉造影检查,并进行颈动脉二维彩色多普勒超声和实时三维超声检查判断颈动脉斑块类型,分析其与冠状动脉病变支数、冠脉狭窄程度的关系,分析实时三维超声检查在冠心病危险评估中的作用。结果:两组颈动脉斑块比较差异有统计学意义(P0.05),且随着冠状动脉病变累及支数的增加,斑块检出率明显增加;多支病变组与单支病变组的颈动脉斑块比较差异有统计学意义(P0.05),病变支数越多者,颈动脉斑块发生率越高;且斑块多为软斑块、含有软斑块为主的混合性斑块。实时三维超声对软斑和混合斑检出率在单支病变组及多支病变组与二维超声比较差异均有统计学意义(P0.05)。因此颈动脉粥样斑块的存在可以预诊冠状动脉粥样硬化的存在,颈动脉粥样硬化与冠状动脉粥样硬化呈明显的相关性。对软斑、混合斑的检出率及斑块表面溃疡检出率方面实时三维与二维超声比较差异有统计学意义(P0.05)。实时三维超声对颈动脉斑块表面有无溃疡检测优于二维超声。结论:颈动脉实时三维超声检查,可间接评估冠状动脉粥样硬化程度,有效预测患者发生心血管不良事件的几率。     

老年脑梗死与颈动脉粥样硬化关系的研究

目的通过对颈动脉内中膜厚度的检测,以探讨颈动脉粥样硬化病变发生率与脑梗死的关系.方法采用B型超声测定颈动脉内中膜厚度和粥样硬化斑块指数.检测130例,脑梗死组65例,对照组65例.结果在脑梗死组颈动脉内中膜厚度明显大于对照组(P＜0.01),颈动脉管腔直径两组无显著性差异.动脉粥样硬化斑块检出率在两组中均以球部为最高,其次为颈总动脉和颈内动脉.脑梗死组颈总动脉硬化发生率、颈动脉硬化斑块指数均显著高于对照组(P＜0.01).结论颈动脉粥样硬化严重程度与脑梗死发生率呈正比.     

老年脑梗塞与颈动脉粥样硬化斑块关系的临床观察

目的探讨老年脑梗塞与颈动脉粥样硬化斑块的关系。方法应用彩色多普勒超声仪分别对100例老年脑梗塞患者(脑梗塞组)和50例非脑梗塞患者(对照组)的颈动脉进行检测,观察颈动脉粥样硬化斑块的发生及与血糖、血脂、血浆纤维蛋白原的关系。结果脑梗塞组患者颈动脉粥样硬化斑块发生率为79%,对照组为16%,两组差异有高度显著性(P<0.01)。高血压、血脂异常、糖尿病、LDL升高、高纤维蛋白原是老年脑梗塞颈动脉粥样硬化斑块形成的危险因素。结论颈动脉超声检查可及早发现颈动脉粥样硬化斑块,积极控制危险因素,对预防和治疗老年脑梗塞具有重要意义。     

彩色多普勒超声检查脑梗死患者颈动脉64例临床分析

目的分析研究彩色多普勒超声检查在脑梗死患者颈动脉粥样硬化斑块的临床诊断中的应用价值。方法对64例首次发病的脑梗死患者进行了颈动脉彩色多普勒超声检查,并与非脑梗死对照组进行对比分析。结果 64例脑梗死患者中有颈动脉粥样硬化斑块形成者51例,检出率达79.69%。颈动脉粥样硬化斑块好发于颈动脉分叉处。脑梗死组软斑所占比率明显大于对照组,而对照组扁平斑最多见。结论颈动脉硬化斑块的存在与脑梗死的发生关系密切,彩色多普勒超声能在早期检出斑块,且方法简单、快捷、无创,对颈动脉粥样硬化有很好的诊断价值,对预防和治疗脑梗死有重要的临床意义。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.