基于计量学的我国中药制药专利合作研究

以中国专利数据库为数据来源,采用科学计量学方法,对我国2000-2010年中药制药合作专利数据从授权量、地域分布、主体几方面进行分析,着重探讨合作研发问题,进而反映我国中药领域合作研发现状、合作研发模式及其特点。     

1999～2009年医学院校双语教学研究论文统计分析

目的统计医学院校双语教学研究论文的发表情况,确定核心作者、论文地区分布、论文多产单位分布等情况。方法采用文献计量学方法,对作者发文数量及合作情况、核心作者、地区分布、论文多产单位等进行统计分析。结果 1999~2009年共发表相关论文406篇。合作论文346篇,平均合作率85.22%,平均合作度3.31。发文2篇以上的作者仅11人,占第一作者总数的2.81%,说明未形成核心作者群。作者分布在27个省、自治区、直辖市,广东省作者排名第一,共发文40篇,占发文总数的9.85%。论文多产单位6个,发文95篇,占发文总量的23.4%。结论医学院校双语教学及研究广泛开展,但仍处于初步探索阶段,需进一步深入。     

《中国高等医学教育》杂志2000至2009年论文核心作者分析

运用文献计量学分析方法对2000至2009年《中国高等医学教育》杂志载文作者发文量、合作情况、地区分布、核心作者、论文高产单位等进行统计分析。结果显示,该刊载文的作者合作度和合作率不断提高该刊,拥有一支实力雄厚且趋于稳定的作者队伍,分布范围广,但地区不平衡差异较明显。需加强高校间医学人才的交流和全国医学资源共享。     

1989～2006年我国HIFU文献的定量分析

目的：依据文献计量学原理，探讨我国2006年前HIFU研究领域的文献，从文献量、作者、机构地区分布及文献的期刊分布情况，了解HIFU科研跨学科和地区情况、作者合作类型及特点，确定核心作者、核心机构和核心地区，表现HIFU研究发展的态势。方法：对维普资讯有限公司数据库中收录的2007年前有关超声聚焦文献的全部数据进行文献计量学分析。结果：2007年前共刊出HIFU论文833篇，合作论文686篇，合作率72．87％，合作度为2．78。独著论文312篇（37．45％）。重庆地区186篇（22．33％）居第一位。核心作者134人，发文410篇（49．22％）。高产机构10个，发文249篇（29．89％）。2000年以后，HIFU论文发文和作者合作情况发生了明显的变化，2000—2006年发文792篇HIFU文献中，作者3147人次，单篇论文平均作者数3．72，平均合著率为81．12％。结论：HIFU文献作者分布范围广，论文合作率较高，拥有一支实力雄厚，对刊物影响较大、造诣较深的核心作者群。各地区在HIFU学领域研究中科研力量分布不均衡，重庆地区的HIFU研究机构在该领域中居前列。     

Cancer 1997～2002年论文与作者统计分析

统计Cancer1997-2002六年内论文及作者情况,讨论载文量分布、主题分布、地区分布、作者的合作度、核心作者及多产机构等,对有关数据进行分析,以期对癌症研究有参考价值。     

我国药物不良反应研究文献计量分析

以中国学术期刊网络出版总库为数据源,运用文献计量学方法对2002-2011年间我国药物不良反应研究的相关文献从年代分布、关键词词频、核心作者、期刊来源及基金资助情况等方面进行分析,了解目前我国药物不良反应研究现状,以期为相关部门及人员提供借鉴。     

从著者角度分析《医学信息学杂志》近10年发展

《医学信息学杂志》更名10年之际,从著者角度回顾过往承启开来。利用清洗后的中国知网文献数据,统计2006-2015年间的文章数量、作者数量和合作程度,以及地域覆盖情况;对高产作者的高频发文、地域和机构分布、新老作者结构等情况进一步深入分析,同时展示高被引文章的具体情况;基于发文量和被引频次运用综合指数法对近10年的核心作者进行测评;多个层次剖析期刊的影响力和发展能力,最后提出几点改进建议。     

2008年～ 2012年《中华医学教育杂志》论文作者分析

本文对2008年～2012年《中华医学教育杂志》刊出论文作者的情况进行了统计分析.分析指标有作者发文量、合作情况、高产作者、基金来源和分布、地区分布、机构分布、高产机构等.结果表明,该刊作者分布范围、合作率高,并拥有一支实力雄厚,对刊物影响较大、造诣较深的活跃核心作者群,基金项目论文逐年提高,北京、广东和湖北地区医学教育研究领域力量雄厚,总体分布尚不均衡.     

《中华医院管理杂志》核心作者文献计量分析

采用文献计量学方法,对《中华医院管理杂志》2003-2006年论文作者发文量、合作情况、地区分布、核心作者、论文多产单位等进行统计分析。《中华医院管理杂志》作者分布范围广、合作率高,并拥有一支实力雄厚、对刊物影响较大、造诣较深、活跃的核心作者队伍。     

2001～2006年《中国医院》杂志论文作者分析

目的：探讨《中国医院》杂志载文作者、机构、地区分布情况，了解科研人员合作类型及特点，确定核心著者、核心机构和核心地区。方法：用文献计量学方法对该刊2001～2006年论文作者发文量、合作情况、地区分布、系统分布、核心作者、高产单位等进行统计分析。结果：该刊6年发文2732篇，发文一篇作者1212人，作者合作论文1336篇，合作率49．76％，合作度2．03，附属医院发文913篇（35．08％），省市医院发文697篇（26．79％），管理机构发文280篇（10．76％），核心著者39人，发文384篇，高产单位13个，发文359篇，北京地区发文737篇，居第一位。结论：该刊作者分布范围广，合作率高，并拥有一支实力雄厚，对刊物影响较大、造诣较深的活跃核心作者群。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.