Clinical Study of the Therapeutic Effectsof Rhubarb as A Main Drug in the Treatment of Chronic Renal Failure

ＣｌｉｎｉｃａｌＳｔｕｄｙｏｆｔｈｅＴｈｅｒａｐｅｕｔｉｃＥｆｆｅｃｔｓｏｆＲｈｕｂａｒｂａｓＡＭａｉｎＤｒｕｇｉｎｔｈｅＴｒｅａｔｍｅｎｔｏｆＣｈｒｏｎｉｃＲｅｎａｌＦａｉｌｕｒｅＹｅＲｅｎ－ｇａｏ（叶任高）；ＬｉＹａｎ－ｃｈｕｎ（李彦春）；ａｎｄ...     

Clinical Effects of Lithospermum Ruderal on Medical Abortion by Mifepristone

ＣｌｉｎｉｃａｌＥｆｆｅｃｔｓｏｆＬｉｔｈｏｓｐｅｒｍｕｍＲｕｄｅｒａｌｏｎＭｅｄｉｃａｌＡｂｏｒｔｉｏｎｂｙＭｉｆｅｐｒｉｓｔｏｎｅｗｉｔｈＭｉｓｏｐｒｏｓｔｏｌＦａＹｕｎ－ｙｕ（法韫玉）；ＬｉｕＪｉａｎ－ｈｕａ（刘建华）；ＳｕｎＨｕａ（孙桦）ａｎ...     

Determination of Serum Osteocalcin in Middle and Elderly Aged Healthy Subjects

ＤｅｔｅｒｍｉｎａｔｉｏｎｏｆＳｅｒｕｍＯｓｔｅｏｃａｌｃｉｎｉｎＭｉｄｄｌｅａｎｄＥｌｄｅｒｌｙＡｇｅｄＨｅａｌｔｈｙＳｕｂｊｅｃｔｓＺｈｕＪｉａｎｚｈｏｎｇ；（朱建中）ａｎｄＧｅＷｅｉ；（葛炜）（ＨａｎｇｚｈｏｕＳａｎａｔｏｒｉｕｍｏｆＰＬＡ，Ｈ...     

Direct Measurement of Oxygen Free Radicals of the Liver Tissue Following Shock/Reperfusion and Its Significance

ＤｉｒｅｃｔＭｅａｓｕｒｅｍｅｎｔｏｆＯｘｙｇｅｎＦｒｅｅＲａｄｉｃａｌｓｏｆｔｈｅＬｉｖｅｒＴｉｓｓｕｅＦｏｌｌｏｗｉｎｇＳｈｏｃｋ／ＲｅｐｅｒｆｕｓｉｏｎａｎｄＩｔｓＳｉｇｎｉｆｉｃａｎｃｅＺｈａｏＺｈｉｑｕａｎ（赵志泉）ＸｕＳｈｕｎｆｕ（徐顺福...     

Clinical Study of Blastocyisasis in Children of Fuzhou District

ＣｌｉｎｉｃａｌＳｔｕｄｙｏｆＢｌａｓｔｏｃｙｉｓａｓｉｓｉｎＣｈｉｌｄｒｅｎｏｆＦｕｚｈｏｕＤｉｓｔｒｉｃｔＷｕＢｉｎ（吴斌）；ＺｈａｏＺｉｑｉｎｇ（赵子庆）；ＨｕａｎｇＭｉａｏｈｕｉ（黄妙辉）ａｎｄＳｕＱｉｎｇｐｉｎｇ（苏庆平）（ＴｈｅｌｓｔＡｆ...     

The Morphological Studies on M2/t(8;21)Acute Nonlymphocytic Leukemia

（程范军）（杨爱德）（费洪宝）ＴｈｅＭｏｒｐｈｏｌｏｇｉｃａｌＳｔｕｄｉｅｓｏｎＭ２／ｔ（８；２１）ＡｃｕｔｅＮｏｎｌｙｍｐｈｏｃｙｔｉｃＬｅｕｋｅｍｉａ￥ＣＨＥＮＦａｎ－ｊｕｎ，ＹＡＮＧＡｉ－ｄｅ，ＦＥＩＨｏｎｇ－ｂａｏ（ＲｅｓｅａｒｃｈＩｎｓｔｉ...     

Shiftwork and Heat Stress in an Intensive Care Unit

ＳｈｉｆｔｗｏｒｋａｎｄＨｅａｔＳｔｒｅｓｓｉｎａｎＩｎｔｅｎｓｉｖｅＣａｒｅＵｎｉｔＬＩＵＬｉ－ｗａｎｇ（刘理望）（ＩｎｓｔｉｔｕｔｅｏｆＯｃｃｕｐａｔｉｏｎａｌＭｅｄｉｃｉｎｅ，ＴｏｎｇｊｉＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ，Ｗｕｈａｎ）Ｃｏｓｔ...     

YU Jin (俞 瑾) -- A Celebrated Gynecotokologist of Integrated Medicine

ＰｒｏｆｅｓｓｏｒＹＵＪｉｎ,Ｍ．Ｄ．,ｂｏｒｎｉｎＳｕｚｈｏｕ,ＪｉａｎｓｕＰｒｏ ｖｉｎｃｅ,ｉｎＯｃｔｏｂｅｒ1 933,ｗａｓｇｒａｄｕａｔｅｄｆｒｏｍＴｈｅＦｉｒｓｔＭｅｄｉ ｃａｌＣｏｌｌｅｇｅｏｆＳｈａｎｇ ｈａｉＭｅｄｉｃａｌＣｏｌｌｅｇｅｉｎ1 95 5ａｎｄｔｈｅｎｃｏｍ ｐｌｅｔｅｄｈｅｒｃｏｕｒｓｅｆｒｏｍＳｈａｎｇｈａｉＳｅｃｏｎｄＲｅｓｅａｒｃｈＣｌａｓｓｏｎＴｒａｄｉｔｉｏｎ ａｌＣｈｉｎｅｓｅＭｅｄｉｃｉｎｅ（ＴＣＭ）（1 95 8- 1 96 1）．Ｓｈｅｈａｄｂｅｅｎｄｅｄｉｃａｔｉｎｇｈ…     

Clinical Measurement of Antibodies against Acetylcholine Receptor（AchR），SOD and LPO in Patients with Myasthenia Gravis（MG） be

ＣｌｉｎｉｃａｌＭｅａｓｕｒｅｍｅｎｔｏｆＡｎｔｉｂｏｄｉｅｓａｇａｉｎｓｔＡｃｅｔｙｌｃｈｏｌｉｎｅＲｅｃｅｐｔｏｒ（ＡｃｈＲ），ＳＯＤａｎｄＬＰＯｉｎＰａｔｉｅｎｔｓｗｉｔｈＭｙａｓｔｈｅｎｉａＧｒａｖｉｓ（ＭＧ）ｂｅｆｏｒｅａｎｄａｆｔｅｒＴｈ...     

Clinical Study on Effects of Buyang Huanwu Decoction on Coronary Heart Disease

ＣｌｉｎｉｃａｌＳｔｕｄｙｏｎＥｆｆｅｃｔｓｏｆＢｕｙａｎｇＨｕａｎｗｕＤｅｃｏｃｔｉｏｎｏｎＣｏｒｏｎａｒｙＨｅａｒｔＤｉｓｅａｓｅＺＨＡＮＧＨｕａｎｇ（张华）；ＬＩＡＮＧＭｕ－ｊｕｎ（梁慕筠）；ＭＡＺｈｉ－ｘｉｏｎｇ（马志雄）ａｎｄＹＥＳｕｉ－ｌ...     

大鼠三叉神经尾侧亚核丘脑投射神经元与初级传入和中缝大核下行投射纤维间的突触联系

用束路追踪和免疫电镜方法研究了大鼠三叉神经尾侧亚核丘脑投射神经元与初级传入和中缝大核下行投射纤维间的突触联系。光镜观察发现，HRP跨节标记三叉神经传入终末与中缝大核（RMg）顺行追踪的PHA－L标记终末在三叉神经尾侧亚核（Vc）浅层有重叠分布。在Vc浅层丘脑投射神经元与初级传入和RMg下行投射的分布也有重叠。电镜观察发现初级传入终末和丘脑投射神经元树突形成非对称性轴树突触；而RMg下行投射终末与三叉丘脑投射神经元树突形成对称性或非对称性轴树突触，提示RMg下行投射纤维可能通过直接作用于丘脑投射神经元对初级传入的伤害性信息进行调控。     

Ultrastructure of the marginal division in the rat striatum.

The discovery of a new subdivision in the striatum of the rat, the marginal division, has recently been reported. The marginal division is located at the caudal extent of the striatum, surrounding the rostrolateral border of the globus pallidus, and has different cellular morphology, immunohistochemistry and an efferent projection pattern from those of the main body of the striatum. In the present study, the ultrastructural organization of the marginal division was investigated. Most neuronal somata in the marginal division were fusiform in shape and had a large pale oval nucleus without in-foldings. There were four types of synapses in the marginal division: axo-somatic, axo-dendritic, axo-spinous and axo-axonic. Both symmetric and asymmetric synapses were observed on the somata, dendrites, or dendritic spines. Most of the symmetric synapses contained pleomorphic vesicles, whereas the asymmetric ones contained mainly round vesicles. Individual axo-axo-spinous synapses, which were first described in the striatum, were also observed in the marginal division. These ultrastructural characteristics distinguish the marginal division from the rest of the striatum.

     

大鼠Meynert基底核注入海人藻酸后c-fos原癌基因蛋白在脑纹状体边缘区及边缘系统内的表达

为研究Meynert基底核与纹状体边缘区以及脑内其他跟学习记忆有关的边缘系统结构间的关系,将海人藻酸注射于大鼠Meynert基底核后,观察c－fos原癌基因蛋白在脑内的表达。海人藻酸注射4h后,脑内只有少量c－fos阳性表达：海人藻酸注射8h后,脑内c－fos原癌基因蛋白表达增至最高峰。在海马、齿状回、中央杏仁核、纹状体、边缘区中有大量密集的c－foc阳性表达。在终纹床核、丘脑网状核、外侧隔核、丘脑下部视上核、室旁核、前下托及嗅内皮质等处可见较多c－foc阳性表达。在伏隔核、视前区、丘脑底核、黑质外侧部等部位可见少量c－fos阳性表达。海人藻酸注射Meynert基底核16h后,除海马、齿状回、中央杏仁核、纹状体及边缘区中有较多表达外,其余部位阳性标记基本消失。但脑腹侧的梨状前皮质、嗅结节、杏仁皮质核及前嗅核等部位出现大量的c－fos阳性表达。大脑皮质也可见较多c－fos阳性表达。海人藻酸注射48h后,脑内各部位的c－fos阳性反应均消失。本研究结果提示Meynert基底核和纹状体边缘区以及跟脑内其它与学习记忆有关的边缘系统结构间有密切的功能联系。     

大鼠中脑至上丘的传入投射

目的：研究大鼠中脑核团到上丘的传人纤维投射。方法：应用荧光金(FG)逆行追踪技术研究大鼠上丘传人纤维的中脑起源。结果：对侧上丘(SC),同侧下丘(IC),外侧丘系背侧核(dll),中央灰质(CG)和双侧黑质(SN),中脑深核(dpM),视束核(ot),二叠体旁核(pbg)观察到FG逆行标记细胞。结论：上丘存在复杂的纤维联系,参与多种生理活动。     

大鼠中缝背核内一氧化氮合酶阳性神经元向伏隔核的投射

目的:观察大鼠中缝背核内一氧化氮合酶(NOS)阳性神经元向伏隔核的投射,为阐明一氧化氮(NO)在中缝背核与伏隔核的纤维联系中的作用提供有价值的形态学依据。方法:用还原型尼克酰胺腺嘌呤二核苷酸脱氢酶(NADPH d)法结合辣根过氧化物酶(HRP)逆行追踪法,观察大鼠中缝背核内NOS阳性神经元向伏隔核的投射。结果:在中缝背核内观察到HRP/NOS双标记神经元,所占比例为5%。结论:中缝背核内有NOS阳性神经元向伏隔核投射。     

Expression of substance P receptor gene in the brain and marginal division of rat striatum-oligonucleotide probes in situ hybridization study

Themarginaldivision(MrD)isadistinctsubterritoryofneostriatumdiscoveredbyShuSY[11etalintheratbrainin1987.Itlocatesatcaudalextentoftheneostriatum,andsurroundstherostralandlateraledgeoftheglobuspallidus.TheMrDismuchdarkerstainedwithL--enkephalin,substanceP,dynorphinB--positiveneuronsthantherestpartofthestriatumZ~'.FiberconnectionswerefoundbetweentheMrDandthehasalnucleusofMeynertsandthesubstantianigra".".TheMrDhasbeensuspectedhavingcloserelationwithlearn.lugandmemoryfunctionsL7j.Chudlereta…     

5-羟色胺能神经元向三叉神经运动核和感觉核的投射

目的 观察５－羟色胺（５－ＨＴ）能神经元向三叉神经运动核（Ｕｍ）和三叉神经脊束核尾侧亚核（Ｖｃ）的投射。方法 荧光金（ＦＧ）逆行单标或ＦａｓｔＢｌｕｅ（ＦＢ）和Ｄｉａｍｉｄｉｄｎｏ Ｙｅｌｌｏｗ（ＤＹ）逆行双标与免疫荧光组化染色相结合的双重或三重标记技术。结果 将ＦＧ注入Ｖｍ或Ｖｃ后,在中缝核簇和中脑导水管周围灰质内可见ＦＧ逆标并呈５－ＨＴ样阳性的双重标记神经元;将ＦＢ和ＤＹ同时分别注入Ｖｍ和Ｖｃ     

豚鼠耳蜗核SP阳性神经元向下丘的投射-HRP逆行追踪与免疫组化双标

目的 研究豚鼠耳蜗核P物质（SP）免疫反应阳性产物的分布特点及SP标记神经元向下丘投射方式。方法 采用辣根过氧化物酶（HRP）逆行追踪及免疫组织化学技术。结果 SP免疫反应（SP－IR）阳性的纤维和终末主要分布在耳蜗背侧核,而SP－IR阳性神经元主要分布在耳蜗腹侧核,在腹侧核尚可见SP阳性终末包绕SP阳性胸体形成环形结构,一侧下丘中央核注入HRP后,对侧耳蜗核HRP标记细胞分布于耳蜗前腹核及背侧核,耳蜗后腹核呈阴性反应。同侧耳蜗后腹核HRP标记神经元数量也较少,在对侧耳蜗前腹核,HRP－SP双标神经元约占标记细胞的44％,SP单标细胞占标记细胞的50％,HRP单标细胞占6％。耳蜗背侧核内侧也可见少量的双标细胞。结论 SP是耳蜗核上行投射神经元的递质或调质。     

豚鼠内侧膝状体背侧核SP阳性神经元向下丘投射

目的：观察下丘（ＩＣ）至内侧膝状体（ＭＧＢ）神经纤维的投射方式,以及内侧膝状体ＳＰ阳性神经元向下丘中央核团的下行投射。方法：采用辣根过氧化物酶（ＨＲＰ）追踪和ＳＰ免疫组化染色。结果：内侧膝状体腹,背侧核均可见ＳＰ免疫反应阳性的神经元,神经纤维和终末。神经元多呈圆形,椭圆形,梭形或不规则形,大小不等,含二个或多个突起,左侧下丘中央核团注入ＨＲＰ后,同侧ＭＧＢ可见分布密集的标记终末。在背侧核,可见ＨＲ     

大鼠脑干5－羟色胺神经元至腰骶髓的投射研究

应用辣根过氧化物酶（ＨＲＰ）逆行追踪法结合免疫细胞化学双重标记法，观察了大鼠脑子５－羟色胺（５－ｈｙｄｒｏｘｙｔｒｙｐｔｍｉｎｅ，５－ＨＴ）神经元向脊髓腰６（Ｌ６）和骶１（Ｓ１）节段的纤维投射。结果表明：在脑桥尾侧网状核、前庭神经外侧核、巨细胞网状核、外侧旁巨细胞网状核、外侧网状核三叉下亚核、中缝大核及中缝苍白核出现ＨＲＰ－５－ＨＴ双标记细胞。提示Ｌ６和Ｓ１节段的５－ＨＴ传入纤维起源是广泛的，不仅延髓网状结构，而且脑桥网状结构和脑神经核内的５－ＨＴ能神经元也向Ｌ６和Ｓ１投射。