分经论治顽固性头痛1则

《内经》始称头痛为“首风”、“脑风”，汉．张仲景指出头痛有太阳、阳明、少阳、厥阴之别，金元．李杲明确提出头痛有外感和内伤之分。头痛是临床上常见的一种症状．可单独出现．亦可出现在各种疾病中。笔者于临床分经论治头痛．辨证结合脏腑。使治疗靶位更准确，疗效更加显著。兹介绍治疗顽固性头痛病案1则如下：     

头痛论治刍议

头痛论治刍议张正威内蒙古东胜市人民医院（０１７０００）头痛是临床上最常见的自觉症状，可见于多种急慢性疾病之中。风为百病之长，是六淫病邪中主要致病因素。风为阳邪．易袭阳位。头者．诸阳所聚之处。头居人体最高部位．高巅之上．惟风可到。可是，风不但是外感头痛...     

运用经方合方治疗头痛医案4则

正头痛是临床常见自觉症状,按传统辨证思路,常采用脏腑经络辨证,辨外感与内伤,辨头痛的性质与部位,多从风、痰、火、瘀、虚等论治,并加以引经药。柯琴言:"仲景六经,为百病立法",头痛亦不逾百病之外。六经辨证治疗头痛,有别于脏腑辨证,也不是按疼痛部位的经络归属分经论治,而是根据患病机体的症状反应的一般规律上辨别六经,并结合水饮、痰湿、瘀血等病因辨出方证、药证,契合病机而处方用药。笔者宗仲景六经辨证规律,运用经方治疗头痛顽疾,列举     

李时珍脑病用药发微

李时珍脑病用药发微朱祥麟（湖北鄂州市中医院鄂州４３６０００）脑作为元神之府，同脏腑一样也会因六淫七情等内外因素致病。但在以五脏为中心的理论系统中，脑是隶属于脏腑的，元神虽发自脑腑，其作用则体现于脏腑百骸，故其为病亦从脏腑论治。李时珍对脑病的治疗与用药...     

从“滞”探析功能性胃肠病的发病观＊

《罗马IV：功能性胃肠病 肠-脑互动异常》中，功能性胃肠病（functional gastrointestinal disorders，FGIDs）又被称之为肠-脑互动异常。针对现代FGIDs疾病谱的变化及FGIDs致病因素的多元化，在“现代”“三因”致病因素的反复作用下，脾胃虚弱，升降失常，气机“凝滞”，产生了FGIDs胃肠道症状，同时，FGIDs患者常具有慢性头痛、呼吸困难、心慌、肌肉疼痛等胃肠道以外症状。FGIDs属于中医脾胃系统疾病，其临床症状与中医脾胃功能失常密切相关，“脾胃虚滞”是FGIDs基本病机，临床可从“滞”论治FGIDs。FGIDs患者症状重叠现象极为常见，FGIDs临床常见八滞：虚滞、气滞、血滞、火滞、湿滞、痰滞、食滞、寒滞。FGIDs临床常用祛滞八法：健补脾胃祛滞法、疏肝理气祛滞法、活血化瘀祛滞法、泻肝行湿祛滞法、燥湿运脾祛滞法、理气化痰祛滞法、消食化痰祛滞法、温胃散寒祛滞法。进一步探析“脾胃虚滞”理论及从“滞”论治FGIDs理论，对现代FGIDs及脾胃相关病的防治具有重要的临床指导意义。     

田金洲运用川芎治疗内伤头痛经验撷英

田金洲教授治疗内伤头痛强调务必详辨头痛部位、疼痛性质、疼痛程度、发作和持续时间、发作诱因及伴发的兼证，以确定其表里寒热、阴阳虚实及脏腑经络。田教授认为风、火、痰、瘀、虚皆为致病因素，治疗不离活血化瘀、通络解痉之法。其运用川芎治疗内伤头痛，配以疏风、疏肝、清火、活血、养血之品，剂量精准，引经报使，配伍巧妙，临床每获良效。     

从血气伏毒构建冠心病中西医融合证治范式

提出融合中西医理论治法,即既具中国传统医学原创、又具现代医学融通的冠心病"中国医学"防治范式。认为脏腑功能失调血气失和与膏脂运化失常是致病基础,瘀毒、痰毒、热毒、脂毒、糖毒、寒毒等伏毒酿生为致病因素,风常为诱发因素,血气失和、伏毒损脉、痰瘀作核是基本病机,脉核阻络或风邪引动伏毒致心脉不利甚或闭阻、心失所养为临床终点。提出护脉-通脉-养脉分期论治、中医"调理"与西医"修理"融通的中西医融合冠心病诊治体系。     

从痰湿辨治椎动脉型颈椎病的临床探讨与研究

椎动脉型颈椎病是颈椎病的常见类型之一，临床以眩晕、头痛或猝倒、颈项板硬、疼痛、胸闷、恶心呕吐等症状为主。虽然《中医病证诊断疗效标准》中将该病分为痰湿阻络、肝肾不足、气血亏虚三个证型，然本病病机多以痰湿变化为基础，故在临床治疗上笔者从痰湿论治，结合脏腑虚损、气血病机等变化而进行相关用药调整，临床观察效果良好，现报道如下。     

袁红霞治疗溃疡性结肠炎验案举隅

袁红霞教授对溃疡性结肠炎的临床诊疗具有独到的见解,认为本病病位虽在大肠,但脾虚是发病基础,病及肺肝肾,湿邪是主要致病因素,瘀血既是病理产物,又是致病因素。治疗多从整体论治,重视脏腑之间的相互关联,以健脾为主,结合疏肝、温肾之法,同时亦多用平调寒热、调和气血之法。     

亥时头痛验案举隅

头痛为临床常见症状,目前从"六经病欲解时"角度论治获效颇佳。文章选取王蕾主任医师从太阴论治亥时头痛医案一则,以分享临证经验。     

微波消解-电感耦合等离子体质谱法测定脉络宁注射液中25种矿物质元素

目的建立微波消解-电感耦合等离子体质谱(ICP-MS)直接稀释测定脉络宁注射液中25种矿物质元素(Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V、As、Cd和Hg)的方法。方法分别对微波消解条件和测试条件进行考察;样品经微波消解后,采用电感耦合质谱仪测定25种矿物质元素,并对测定方法学进行考察。结果确定最佳消解条件为3步缓慢升温:400 W 80℃升温10 min,保留5 min;600 W 120℃升温10 min,保留5 min;900 W 200℃升温20 min,保留20 min;25种矿物质元素在各自的线性范围内线性关系良好,r≥0.999 6,精密度、稳定性和重复性试验的RSD均符合定量分析要求;加标回收率为94.7%~106.1%,RSD在0.34%~2.79%。脉络宁注射液中检测出Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V,未检出As、Cd和Hg。结论该方法简便、迅速、准确,适用于脉络宁注射液中25种矿物质元素的同时测定。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

Journal of Acupuncture and Tuina Science Instructions for Authors

The Journal of Acupuncture and Tuina Science, a journal with an international scope （IS SN 1672-3597, CN 31-1908/R, Bimonthly）, is embodied by ＇Springer Verlag＇ Database, Index Copernicus （IC） and Chinese Scientific and Technical Paper and Citations Data （CSTPCD）. You can search full text on http：//www, springerlink, com/content/1672 -3597.     

Yerba Mate or Paraguay Tea

正Beverages based on Ilex paraguariensis A.St.-Hil.are used in the south Brazil and other Latin American countries located at the so-called southern cone.It is known as chimarro or mate in south and southeast Brazil,tererêin     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.     

Veränderungen der Herzratenvariabilität (HRV) während Low Level Lasernadelakupunktur: Placebokontrollierte Studie an 19 herzgesunden Probanden

Background

Experimental and clinical studies postulate a neurobiological mechanism of acupuncture by modulating central pain systems, neurohormones and -transmitters. It seems to be quite likely that the autonomic nervous system (ANS) plays an important mediating role in this neuromodulation.

Aim

In measuring heart rate variability (HRV), as a non-invasive approach to the ANS-function, the object of this study was to monitor probable acupuncture-induced changes of autonomic balance. The innovative technology of laser-needle acupuncture offers for the first time a stimulation method which fulfils the demands on a placebo-controlled acupuncture trial not requiring controversial sham acupuncture.

Method

19 healthy voluntary subjects underwent 3 treatments in randomized sequence, consisting of placebo-, 1-point- (PC 6) and simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle-stimulation over 20 minutes. Before, during and after placebo-/verum laser-needle acupuncture, HRV-data for normalized HF(high frequency)- and LF(low frequency)-Power (nHF, nLF) and their quotient nLF/nHF obtained by power spectrum analysis (FFT), were measured and analyzed statistically at 5 different time points (ANOVA repeated measures, p < 0,05).

Results

During both verum applications, the 1-point- (PC 6) as well as the simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle stimulation, significant changes of the ANS-activity were found in comparison to the placebo application. The most significant modification of HRV was an increase of nHF (p < 0,05 (PC 6), p < 0,0001 (PC 6, LR 3, SI 3)) as an expression of growing vagal activity during acupuncture.

Conclusion

Laser-needle acupuncture causes in 1-point-stimulation (PC 6) as well as in simultaneous 3-point-stimulation (PC 6, LR 3, SI 3) significant changes in HRV in comparison to placebo application. HRV-monitoring seems to be a suitable approach in exploration of acupuncture-induced changes of ANS and could possibly be established in combination with laser needle acupuncture as a standard for further scientific and clinical acupuncture investigations which are greatly needed.     

瑞香科五属植物中酚性聚合物的结构特征、分布及药理活性研究进展

瑞香科植物广泛分布于世界热带和温带地区,其中多种植物可供药用。在对该科植物的研究中发现,黄酮类、木脂素和香豆素等酚性化合物的低聚体为其重要的特征性成分,药理活性主要表现在抗肿瘤、抗炎、抗氧化、抗菌和抗病毒等方面。对已发现的酚性聚合体的化学结构、植物来源及药理活性进行综述,为瑞香科植物今后的研究和开发利用提供参考。     

HPLC法同时测定沉香化滞丸中11种成分

目的采用HPLC梯度洗脱法同时测定沉香化滞丸中沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚11种成分。方法采用Thermo Syncronis C18色谱柱(250 mm×4.6 mm,5μm),流动相为水-乙腈,梯度洗脱:0～10 min,20%乙腈;10～20 min,20%～40%乙腈;20～24 min,40%乙腈;24～26 min,40%～52%乙腈;26～30 min,52%乙腈;30～31 min,52%～90%乙腈;31～35 min,90%乙腈;35～40 min,90%～100%乙腈;40～43min,100%乙腈;43～45min,100%～20%乙腈;检测波长215nm,体积流量1.0m L/min,柱温30℃,进样量20μL。结果各成分在43 min内分离良好,沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚的线性范围分别为1.4～13.6、10.0～200.0、31.5～315.0、1.0～120.1、1.8～50.6、0.93～10.1、1.8～30.0、0.2～40.3、1.8～18.1、1.7～25.0、0.45～10.70μg/mL;样品中各成分的平均回收率均在98.90%～100.87%;11种成分精密度RSD在0.55%～1.54%;供试品溶液在30 h内稳定性良好,RSD在0.75%～1.94%;重复性RSD在0.39%～1.73%。6批次样品中沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚质量分数分别为92.0～201.0、511.5～9 033.0、5 475.0～12 635.5、54.5～5 095.5、192.0～2 137.5、117.0～391.5、106.5～1 281.5、13.0～136.5、93.5～199.0、177.0～1 207.0、33.5～251.5μg/g。结论本方法准确、快速、简便,重复性好,精密度高,适用于沉香化滞丸中多种活性成分的定量分析。