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1.
目的:探讨改良腹膜外淋巴结清扫术及阴式广泛性子宫切除术在浸润型宫颈癌治疗中的应用价值.方法:2004年10月至2006年10月,我们对18例Ⅰ A2期至ⅡA期的宫颈癌患者实施了经腹的腹膜外淋巴结清扫术及经阴道广泛子宫切除术.腹部淋巴结清扫的单侧切口长约5 cm.在经阴道的广泛子宫切除术时,无需行Schuchardt切口,而是首先切除宫骶韧带,再游离输尿管.结果:18例手术均获成功,平均手术时间212±20.32分钟,平均出血量530±35.12ml,平均术后肛门排气时间26±4.15小时,平均清扫盆腔淋巴结数目31±2.23个.术后无尿潴留发生.结论:改良腹膜外盆腔淋巴结清扫术及经阴道广泛子宫切除术安全可行;并可先于输尿管游离之前,切除宫骶韧带,有利于充分暴露术野,有利于打开输尿管隧道.  相似文献   

2.
Yang ZJ  Chen YL  Yao DS  Zhang JQ  Li F  Li L 《中华妇产科杂志》2011,46(11):854-859
目的 探讨腹腔镜下广泛性子宫切除术[即腹腔镜下广泛性子宫切除+盆腔淋巴结切除术( LRH+ LPL)]治疗早期(Ⅰa2~Ⅱa期)宫颈癌的疗效及对患者预后和生命质量的影响.方法 回顾性分析2002年1月1日至2011年1月1日在广西医科大学附属肿瘤医院妇瘤科行LRH+ LPL的85例早期宫颈癌患者(腹腔镜组)和行开腹广泛性子宫切除术[即开腹广泛性子宫切除+盆腔淋巴结切除术( ARH+ APL)]的85例早期宫颈癌患者(开腹组)的临床病理资料,采用欧洲癌症研究与治疗组织(EORT)的生命质量核心量表——EORTC2C30及自制的特异性量表对存活患者进行生命质量调查,比较两组患者的疗效及生命质量调查结果,并采用Cox比例风险模型分析影响患者预后的因素.结果 腹腔镜组中2例患者中转开腹,其他患者均成功完成了LRH+ LPL.与开腹组相比,腹腔镜组的手术时间[腹腔镜组和开腹组分别为( 242±74)和(190±61) min,P=0.000]明显增加,术中出血量[分别为( 367±252)和(460±220)ml,P=0.006]明显减少,术后肛门排气时间[分别为(45±7)和(63±11)h,P=0.000]、术后排尿功能恢复时间[分别为(19±4)和(21±4)d,P=0.000]明显减少,而盆腔淋巴结切除数目、宫旁组织切除长度、阴道切除长度以及术中、术后并发症发生率无明显差异(P>0.05).开腹组与腹腔镜组患者的复发率和病死率(均分别为7%和5%,P=0.540)、累积5年无瘤生存率(分别为90%和94%,P=0.812)、累积5年总生存率(分别为90%和95%,P=0.532)、生命质量调查结果比较,差异均无统计学意义(P>0.05).Cox比例风险模型分析显示,仅脉管浸润是影响宫颈癌患者预后的独立危险因素(P=0.016).结论 LRH+ LPL治疗早期宫颈癌能达到与ARH+ APL相同的疗效,而术中出血量少,术后恢复快,且患者术后生命质量相似;脉管浸润是影响患者预后的独立危险因素,而手术方式并不影响患者预后.因此,对于有经验的术者,LRH+LPL是治疗早期宫颈癌的一种较为理想的手术方式的选择.  相似文献   

3.
目的:评估腹腔镜保留盆腔神经的广泛性子宫切除术的临床可行性,及其对膀胱与直肠功能的保护作用。方法:比较行LNSRH与腹腔镜下广泛性子宫切除术(LRH)的宫颈癌患者的术中及术后情况。结果:LNSRH组术后拔除尿管及首次排气时间短于LRH组(P=0.039,P=0.041);两组的手术时间、术中失血量、清扫盆腔淋巴结数、宫旁组织切除长度及阴道切除长度均无显著差异(P0.05)。结论:LNSRH可在达到治疗效果的基础上促进患者术后膀胱和直肠功能的快速恢复。  相似文献   

4.
目的探讨腹腔镜下广泛性宫旁切除术加阴道上段切除术治疗子宫全切术后宫颈癌的安全性及可行性。方法对常州市妇幼保健院2016年12月至2017年12月收治的5例子宫全切术后意外发现的宫颈癌患者行腹腔镜下(次)广泛性宫旁切除术+阴道上段切除术+双侧盆腔淋巴清扫术(其中1例为外院会诊手术),回顾性分析其临床病理资料及随访情况。结果 5例患者平均年龄48.4岁。1例宫颈微偏腺癌,1例宫颈腺鳞癌,1例宫颈腺癌,2例宫颈鳞癌。临床分期ⅠA2期2例,ⅠB1期3例。5例患者两次手术间隔时间平均16d,手术时间平均164min,术中出血量平均120mL。术中无一例输血,未发生手术损伤。无一例发生术后病率。术后拔除尿管时间平均为术后15.2d,残余尿量平均14.8mL,无一例发生尿潴留。5例患者术后病理报告均提示阴道壁及宫旁组织、双侧卵巢未见癌侵犯,但1例宫颈腺癌患者双侧盆腔淋巴结见33枚有癌转移,术后1周开始给予化疗,目前正在放疗随访中。随访过程中无一例发生复发、远处转移及远期并发症。结论腹腔镜下广泛性宫旁切除术加阴道上段切除术治疗子宫全切术后意外发现的宫颈癌是安全、可行的。  相似文献   

5.
Wang YF  Liu L  Liu FH  Su J  Su M  Tan Y  Chen CL 《中华妇产科杂志》2006,41(4):226-228
目的探讨改良的腹式广泛性宫颈切除术在早期宫颈癌手术治疗中的可行性和安全性.方法 2002年10月至2004年9月,对13例Ⅰ期宫颈癌患者,施行腹式盆腔淋巴结切除术,快速冰冻病理检查证实无淋巴结转移后,行改良的腹式广泛性宫颈切除术,保留子宫体,并保持子宫动静脉的完整性.术后随访,观察其复发情况,对其中要求生育者随访其生育情况.结果 13例患者均成功地施行了改良的腹式广泛性宫颈切除术,平均手术时间158 min(135~185 min),术中平均出血量120 ml(100~180 ml).术后无并发症发生,平均住院时间9.7 d.随访1~24个月,无一例复发;5例有生育要求者中3例已成功妊娠,1例孕34周早产,另1例现孕16周,第3例现孕8周,妊娠经过良好.结论改良的腹式广泛性宫颈切除术安全、可行,对要求保留生育功能的早期宫颈癌患者更适宜.  相似文献   

6.
目的 评估腹腔镜下广泛子宫切除术联合盆腹腔淋巴结切除术用于治疗子宫颈癌的临床效果。方法 对57例Ⅰa~Ⅱb期的子宫颈癌患者,施行腹腔镜下广泛子宫切除术联合盆腔及腹主动脉周围淋巴结切除术。其中子宫颈鳞状细胞癌48例,腺癌7例,腺鳞癌2例。结果 除2例外,所有患者均在腹腔镜下完成手术,平均手术时间为186min(150~320min),术中平均出血168ml(120~700ml),切除盆腔和腹主动脉周围淋巴结数量平均为18.6个和8.2个;8例患者淋巴结为阳性。所有切除组织边缘大体检查均为阴性。术中2例膀胱损伤、1例静脉损伤,均于镜下修补成功;2例中转开腹。术后肛门排气时间平均为2.3d,恢复自主排尿时间平均为10.2d。手术后每3个月随访1次,发现轻度输尿管狭窄1例,尿潴留2例,阴道残端复发3例,病情未控1例。结论 腹腔镜下广泛子宫切除术联合盆腹腔淋巴结切除术j治疗子宫颈癌手术创伤小、并发症少、术后恢复快,是一种治疗子宫颈癌的理想方法。  相似文献   

7.
目的:探讨经阴道子宫广泛或次广泛切除加腹腔镜手术治疗子宫恶性肿瘤的可行性和临床效果。方法:对18例宫颈癌患者,5例子宫内膜癌患者,行经阴道子宫广泛或次广泛切除加腹腔镜盆腔淋巴结清除术。分析手术质量和术后恢复情况。结果:23例患者均顺利完成手术,无并发症发生。清除的盆腔淋巴结数平均29个,平均手术时间为216分钟,术中平均出血350 ml,3例需要输血。术后肛门排气时间平均1.8天,膀胱功能恢复时间平均11.5天,平均术后住院时间9.5天。术后第一天均可下地活动。22例无复发。结论:该术式损伤小、恢复快,能达到足够的切除范围,是目前治疗子宫恶性肿瘤较理想的术式。  相似文献   

8.
为探讨老年妇女行子宫广泛切除术的可行性,回顾性分析了子宫广泛性切除对65岁以上妇女及50岁以下的死亡率与并发症。65岁以上行广泛性子宫切除术者62例,平均70岁,每例配对2例50岁以下进行同样手术的妇女作为比较,50岁以下组共124例,平均36岁。所有病例术前均被诊断为宫颈癌FIGO分期Ⅰ_b期,手术范围为子宫广泛切除及盆腔淋巴结清扫术,所有手术均由同一妇瘤专家操作,麻醉选用全麻气管内插管。统计学方法采用t检验。  相似文献   

9.
张治宁   《实用妇产科杂志》2017,33(12):914-917
目的:探讨年轻宫颈癌保留生育功能患者行腹腔镜下盆腔淋巴结切除+阴式广泛宫颈切除术(VRT)后的临床效果及妊娠结局。方法:选择2011年1月至2015年12月就诊于宁夏医科大学总医院行腹腔镜下盆腔淋巴结切除+VRT的早期宫颈癌患者16例(VRT组),同期30例早期宫颈癌行腹腔镜下广泛子宫切除术+盆腔淋巴结切除术(LRH)患者作为对照(LRH组),对比观察两种手术的的临床效果;随访16例患者的累积妊娠率及妊娠结局。结果:两组在年龄、临床分期、病理分化程度、淋巴血管间隙受侵、鳞癌抗原表达、手术时间、术后发热率、术后并发症以及术后复发等指标上差异无统计学意义(P0.05)。VRT组术中出血量、术后住院天数明显优于LRH组(P0.05)。16例腹腔镜下盆腔淋巴结切除+VRT术后1年妊娠12例,累积妊娠次数15次;1年足月产4例次(33.3%),流产11例次(73.3%)。结论:对年轻宫颈癌患者,腹腔镜下盆腔淋巴结切除+VRT手术可达到与广泛子宫切除术+盆腔淋巴结切除术同样临床效果,同时可保留生育功能,但需提高妊娠率及生殖预后。  相似文献   

10.
目的探讨筋膜外全子宫切除术加盆腔淋巴清扫术治疗早期宫颈癌(Ⅰa2~Ⅰb1期)的可行性。方法选择2008年6月至2010年6月在山东省青岛市市立医院行手术治疗的47例早期宫颈癌(Ⅰa2~Ⅰb1期)患者,先行腹腔镜下盆腔淋巴清扫术,术中行冰冻病理检查,如盆腔淋巴结阳性,则按传统手术方式行腹腔镜下腹主动脉旁淋巴清扫或取样+广泛性子宫切除术;如盆腔淋巴结阴性,则行腹腔镜下筋膜外全子宫切除术。所有患者术后如经病理证实有脉管间隙受侵、间质浸润深、盆腔淋巴结转移、宫旁组织阳性或手术切缘阳性,则加用放化疗。术后均严密随访。结果参与随访的42例患者中,1例Ⅰb1期低分化、病灶直径2cm的鳞癌患者术中冰冻提示(右侧)闭孔淋巴结有癌组织浸润,行腹腔镜下腹主动脉旁淋巴清扫+广泛性子宫切除术。其余41例患者均行腹腔镜下筋膜外全子宫切除术。1例Ⅰb1期低分化、病灶直径2cm的腺癌患者,术后病理诊断提示有脉管浸润。未发现宫旁浸润及手术切缘阳性的病例。盆腔淋巴结阳性、脉管浸润的2例患者术后进行了放化疗。平均随访60~84(71.33±7.77)个月,1例出现复发及可疑肺转移;行广泛性子宫切除术的1例患者术后5年复查发现鳞状上皮癌抗原升高,但未发现复发及转移灶,其余患者未发现复发及转移。结论早期宫颈癌(Ⅰa2~Ⅰb1期)患者在盆腔淋巴结无转移的情况下行筋膜外全子宫切除术加盆腔淋巴清扫术可能可行。  相似文献   

11.
Abstract. Fram KM. Laparoscopically assisted vaginal hysterectomy versus abdominal hysterectomy in stage I endometrial cancer.
The purpose of this study was to evaluate and compare laparoscopic treatment for stage I endometrial cancer with the traditional transabdominal approach. From July 1996 to July 1998, 61 patients with clinical stage I endometrial cancer were treated at the Gynaecology Oncology Unit at the Royal North Shore of Sydney, Australia. Twenty-nine patients were treated with laparoscopic assisted vaginal hysterectomy (LAVH) and bilateral salpingo-oophrectomy (BSO) ± laparoscopic pelvic lymphadenectomy (LPLA), while 32 patients were treated with the traditional laparotomy and underwent total abdominal hysterectomy (TAH) and BSO ± pelvic lymphadenectomy (PLA). The main outcomes studied were operative time, blood loss, blood transfusion, intraoperative complications, postoperative complications, duration of hospital stay, and number of lymph nodes obtained. In conclusion, laparoscopic treatment of endometrial cancer is safe in the hands of experienced operators with minimal intraoperative and postoperative complications. This procedure is associated with significantly less blood loss and shorter hospitalization; however, it is associated with significantly longer operating time. Proper selection of patients for the laparoscopic procedure is the vital step in achieving the major goals of this approach.  相似文献   

12.
OBJECTIVE: To compare intraoperative, pathologic, and postoperative outcomes of total laparoscopic radical hysterectomy with abdominal radical hysterectomy and pelvic lymphadenectomy for women with early-stage cervical cancer. METHODS: We reviewed all patients who underwent total laparoscopic radical hysterectomy or abdominal radical hysterectomy and pelvic lymphadenectomy between 2004 and 2006. RESULTS: Fifty-four patients underwent abdominal radical hysterectomy, and 35 underwent total laparoscopic radical hysterectomy. Mean age was 41.8 years, and mean body mass index 28.1. There was no difference in demographic or tumor factors between the two groups. Mean estimated blood loss was 548 mL with abdominal radical hysterectomy compared with 319 mL with total laparoscopic radical hysterectomy (P=.009), and 15% of patients who underwent abdominal radical hysterectomy required a blood transfusion compared with 11% who underwent total laparoscopic radical hysterectomy (P=.62). Mean operative time was 307 minutes for abdominal radical hysterectomy compared with 344 minutes for total laparoscopic radical hysterectomy (P=.03). On pathologic examination, there was no significant difference in the amount of parametrial tissue, vaginal cuff, or negative margins obtained. A mean 19 pelvic nodes were obtained during abdominal radical hysterectomy compared with 14 during total laparoscopic radical hysterectomy (P=.001). The median duration of hospital stay was significantly shorter for total laparoscopic radical hysterectomy (2.0 compared with 5.0 days, P<.001). For abdominal radical hysterectomy, 53% of patients experienced postoperative infectious morbidity compared with 18% for total laparoscopic radical hysterectomy (P=.001). There was no difference in postoperative noninfectious morbidity. There was no difference in return of urinary function. CONCLUSION: Total laparoscopic radical hysterectomy reduces operative blood loss, postoperative infectious morbidity, and postoperative length of stay without sacrificing the size of radical hysterectomy specimen margins; however, total laparoscopic radical hysterectomy is associated with increased operative time.  相似文献   

13.
The aim of this study was to investigate the feasibility and safety of laparoscopic radical parametrectomy and pelvic and para-aortic lymphadenectomy after previous supracervical or extrafascial hysterectomy. This is a prospective study of six patients with vaginal or cervical stump carcinoma after previous supracervical or extrafascial hysterectomy. The technique of radical parametrectomy with pelvic and para-aortic lymphadenectomy as used for open surgical cases for years was performed laparoscopically. The average operating time was 180 min, the estimated average blood loss was 220 mL, and the duration of hospitalization was 11.8 days. There was no intraoperative or postoperative complication. Laparoscopic radical parametrectomy with pelvic and para-aortic lymphadenectomy for cervical or vaginal stump carcinoma can be successfully and safely accomplished.  相似文献   

14.
腹腔镜下淋巴结切除治疗妇科恶性肿瘤的临床分析   总被引:10,自引:1,他引:9  
Liang Z  Xu H  Xiong G  Li Y  Chen Y  Wang L  He W  Shi C 《中华妇产科杂志》2002,37(11):656-659
目的 探讨腹腔镜下广泛子宫切除和盆,腹腔淋巴结切除用于妇科恶性肿瘤的可行性及价值。方法 对子宫内膜癌21例,子宫颈癌25例患者,根据病变部位和淋巴结切除术适应证,行盆腔淋巴结切除术,其中对30例患者行选择性腹主动脉周围淋巴结切除,再行腹腔镜辅助阴式广泛子宫切除术。结果 腹腔镜下手术时间平均为3.1h,术中出血平均198ml。切除淋巴结数平均16个。术后住院时间平均9.6d。术中发生膀胱损伤2例。静脉损伤2例。1例大肠损伤术中转行开腹术,术后仅1例于1个月后出现双侧输尿管轻度狭窄,1例术后1个月出现肿瘤穿刺孔转移,3例出现尿潴留,其余无明显并发症发生。结论 对妇科恶性肿瘤施行腹腔镜下广泛子宫切除和盆,腹腔淋巴结切除术安全可靠;淋巴结切除彻底,且手术创伤小,并发症少,术后恢复快。  相似文献   

15.
OBJECTIVE: Lymphadenectomy is an integral part of staging and treatment of gynecologic malignancies. We evaluated the feasibility and oncologic value of laparoscopic transperitoneal pelvic and paraaortic lymphadenectomy in correlation to complication rate and body mass index. METHODS: Between August 1994 and September 2003, pelvic and/or paraaortic transperitoneal laparoscopic lymphadenectomy was performed in 650 patients at the Department of Gynecology of the Friedrich-Schiller University of Jena. Retrospective and prospective data collection and evaluation of videotapes were possible in 606 patients. Laparoscopic lymphadenectomy was part of the following surgical procedures: staging laparoscopy in patients with advanced cervical cancer (n = 133) or early ovarian cancer (n = 44), trachelectomy in patients with early cervical cancer (n = 42), laparoscopic-assisted radical vaginal hysterectomy in patients with cervical cancer (n = 221), laparoscopy before exenteration in patients with pelvic recurrence (n = 20), laparoscopic-assisted vaginal hysterectomy or laparoscopic-assisted radical vaginal hysterectomy in patients with endometrial cancer (n = 112), and operative procedures for other indications (n = 34). RESULTS: After a learning period of approximately 20 procedures, a constant number of pelvic lymph nodes (16.9-21.9) was removed over the years. Pelvic lymphadenectomy took 28 min, and parametric lymphadenectomy took 18 min for each side. The number of removed paraaortic lymph nodes increased continuously over the years from 5.5 to 18.5. Right-sided paraaortic, left-sided inframesenteric and left-sided infrarenal lymphadenectomy took an average of 36, 28, and 62 min, respectively. The number of removed lymph nodes was independent from the body mass index of the patient. Duration of pelvic lymphadenectomy was independent of body mass index, but right-sided paraaortic lymphadenectomy lasted significantly longer in obese women (35 vs. 41 min, P = 0,011). The overall complication rate was 8.7% with 2.9% intraoperative (vessel or bowel injury) and 5.8% postoperative complications. No major intraoperative complication was encountered during the last 5 years of the study. CONCLUSION: By transperitoneal laparoscopic lymphadenectomy, an adequate number of lymph nodes can be removed in an adequate time and independent from body mass index. The complication rate is low and can be minimized by standardization of the procedure.  相似文献   

16.
Laparoscopic lymphadenectomy was performed on 18 patients with invasive carcinoma of the cervix prior to definitive radiation therapy and/or radical hysterectomy. Ten patients underwent pelvic and para-aortic lymphadenectomies prior to planned radiotherapy. Two of these patients had grossly positive pelvic nodes, and one had a microscopically positive para-aortic node. Eight patients with early disease were considered candidates for radical hysterectomy and underwent laparoscopic lymphadenectomy. Three of these patients were found to have positive pelvic lymph nodes and the hysterectomy was abandoned. Five patients underwent radical hysterectomies immediately following their laparoscopic procedures. The average number of lymph nodes removed laparoscopically in these patients was 31.4; the average number of additional lymph nodes resected at laparotomy with the radical hysterectomy was 2.8. A single microscopically positive parametrial lymph node was found on permanent section in 1 patient with radical hysterectomy. No significant complications were associated with the laparoscopic lymphadenectomies. Nine of the 13 patients who underwent laparoscopic procedures only were discharged on Postoperative Day 1. The ability to perform pelvic and para-aortic lymphadenectomy allows for complete surgical staging of carcinoma of the cervix laparoscopically.  相似文献   

17.
100 years of radical vaginal hysterectomy according to Schauta is an occasion to evaluate the value of this “forgotten” surgical technique. The possibility of laparoscopic removal of paraaortic and pelvic lymph nodes in patients with cervical cancer opened the way for the reintroduction of “Schauta's operation”. In a curative approach to primary tumors lymphonodectomy is performed laparoscopically. In presence of negative lymph nodes and if bladder and rectum are free of disease laparoscopic assisted radical vaginal hysterectomy is performed. A combination of laparoscopic and vaginal surgical techniques permits individualized, risk-adjusted approaches to cervical carcinoma. Even in cases of large tumors, a nerve-sparing approach to radical vaginal hysterectomy results in maintenance of motoric bladder function with high surgical radicality and locoregional safety. It is possible to surgically treat early tumor states by laparoscopically assisted radical trachelectomy to preserve fertility when oncological standards are observed. At present, the laparoscopically assisted radical vaginal hysterectomy and the well-established abdominal Wertheim operation represent two oncologically equivalent surgical procedures available for treatment of early cervical carcinoma.  相似文献   

18.
ObjectiveWe describe a series of patients diagnosed with invasive cervical cancer after undergoing simple hysterectomy who subsequently underwent robotic radical parametrectomy and bilateral pelvic lymphadenectomy. The goal of this study is to report on the safety and feasibility of robotic radical parametrectomy.MethodsA retrospective review was performed of all patients who underwent robotic radical parametrectomy and bilateral pelvic lymphadenectomy at our institution during the period December 2006 to February 2008. We analyzed our data to evaluate the safety and feasibility of performing robotic radical parametrectomy.ResultsThis analysis included 5 patients with invasive squamous cell carcinoma of the cervix. The median body mass index was 23.8 kg/m2 (range, 17.7 to 26.5). The median operative time was 365 min (range, 331 to 430). The median estimated blood loss was 100 mL (range, 50 to 175). There were no conversions to laparotomy. There was 1 intraoperative complication—cystotomy. No patient required blood transfusion. The median length of hospital stay was 1 day (range, 1 to 2). One patient experienced two postoperative complications, a vesicovaginal fistula and a lymphocyst. No patient had residual tumor in the parametrectomy specimen, and no patient underwent adjuvant therapy. The median number of pelvic lymph nodes removed was 14 (range, 6 to 16). The median follow-up for all patients was 7.5 months (range, 1.3 to 13.8). There were no recurrences.ConclusionRobotic radical parametrectomy and bilateral pelvic lymphadenectomy is feasible and safe and can be performed with an acceptable complication rate.  相似文献   

19.
Laparoscopically assisted vaginal radical vaginal hysterectomy (LAVRH), a minimally invasive technique that seems to be an attractive alternative to traditional surgery, remains unexplored in the treatment of cervical cancer. We searched Medline (1966–2013) and Scopus (2004–2013) search engines, as well as reference lists from all included studies. Ten studies were retrieved; including 6 retrospective cohort studies, 2 prospective cohort studies, 1 retrospective randomized trial, and a phase II randomized control trial. LAVRH provided equal recurrence-free rates when performed in patients with tumors not exceeding 2 cm in greatest diameter. Its main advantages seem to be less intraoperative blood loss and more radical pelvic lymphadenectomy. The primary disadvantages of the technique are a higher rate of disease-positive surgical margins, resulting in the need for adjuvant therapy, and the slow learning curve required for a surgeon to gain expertise. With use in minimally invasive surgery of newer techniques such as total laparoscopic radical hysterectomy and robotic-assisted radical hysterectomy, and possible future adoption of more conservative techniques such as cervical conization with pelvic lymphadenectomy, the question remains as to whether LAVRH will be adopted by the surgical community or lost to oblivion.  相似文献   

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