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1.
生物人工肝支持系统(BALSS)是治疗肝功能衰竭的有效方法,已成为国内外的研究热点。BALSS的温度控制不仅直接影响肝细胞的活性及功能表达,而且在系统整体结构优化中也占有重要地位。在设计的新型温控系统中用便于精确控温的半导体加热器作为加热元件,利用基于模糊PID算法的双控温回路来对BALSS进行温度控制,同时在结构设计以及有效传热问题上进行了优化。结果表明此温控系统在控制精度、减小BALSS体积及便于操作等方面均有较大改善。  相似文献   

2.
生物人工肝体外支持系统是治疗肝衰竭的重要研究课题,其核心是生物反应器和具有生物活性的肝细胞。在生物人工肝体外支持治疗过程中,肝细胞的功能活性会发生很大变化,因而有必要监测肝细胞的生存状态信息,以指导临床治疗。丙氨酸氨基转移酶(alanine transaminase,ALT)是临床上普遍认可的评价肝细胞状态的指标。本文以ALT检测为例,设计了一种肝细胞生存状态的在线微检测系统。与常规检测设备的对比实验表明该系统具有较好的重复性,可以代替人工操作,实现在线实时获取肝细胞生存状态信息的功能。  相似文献   

3.
以固定化人工膜(immobilized artificial membrane,IAM)为基质动态固定胰蛋白酶,研究缓冲液种类、浓度、pH值对胰蛋白酶在IAM上的固载率和酶活性的影响。本课题选择硼酸盐、磷酸盐、Tris?HCl三种缓冲液体系,考察了缓冲液浓度及pH值对IAM固载胰蛋白酶的影响,并建立以酪蛋白为底物测定固定化胰蛋白酶的活性的方法,优化了动态固定化胰蛋白酶的条件,为进一步研究在线固定化酶解反应器奠定基础。  相似文献   

4.
20万吨/年产聚酯装置以精对苯二甲酸(PTA)和乙二醇(EG)为原料,采用直接酯化连续缩聚工艺生产而成纤维级聚酯切片。聚酯装置由浆料配制、酯化、切片生产及输送、添加剂配制等几个主要工序组成。酯化缩聚设置了5个反应器,其中两个是酯化反应器,两个是预缩聚反应器,一个是后缩聚反应器。两个酯化反应器为立式搅拌槽,设内盘管液相加热和夹套气相加热,两台反应器共用一个分离乙二醇和水的工艺塔。第一预缩聚反应器为立式槽,不设搅拌装置,用液环真空泵产生真空。第二预缩聚反应器和后缩聚反应器为圆盘转子式,  相似文献   

5.
生物反应器系统参数虚拟测试仪的研制   总被引:1,自引:0,他引:1  
文中简要介绍了生物工程的重要性和生物反应器监控发展概况,以及虚拟仪器在这方面的应用现状和优势。所研制的虚拟仪器可在线检测温度、罐压、溶解氧、pH值、尾气CO2含量等9个参数,充分发挥了虚拟仪器的优势,避免了传统硬件式仪器的不足。着重阐述了生物反应器参数虚拟测试仪的基本结构,在此基础上论述了该虚拟仪器的软件设计和硬件结构,并以温度、pH值为例介绍了它们的检测调理电路。  相似文献   

6.
采用20mL、220mL、10L、100L一次性激流&灌注式生物反应器连续灌注培养BHK-21细胞,通过控制pH、DO等工艺参数,得到稳定的培养BHK-21细胞的大规模培养工艺。从20mL、200mL、10L到100L实现了细胞数的逐级放大,认为该工艺为细胞反应器大规模生产动物疫苗奠定了技术基础。  相似文献   

7.
交替曝气两级生物滤池除磷工艺挂膜启动研究   总被引:4,自引:0,他引:4  
为克服传统BAF工艺生物除磷效果差的缺点,开发了厌氧/好氧交替BAF生物除磷工艺。在水温为25~28℃的条件下,采用3阶段“闷曝阶段、小流量逐渐增加负荷连续进水阶段、交替曝气阶段”的方式启动交替曝气两级生物滤池反应器,前2阶段主要是培养好氧异养菌,第3阶段是培养驯化除磷微生物。试验结果表明,经前2阶段后,COD去除率为76.09%;第3阶段结束时,TP去除率为72.31%,COD去除率达到80%以上。本反应器挂膜启动完成时间为14d。  相似文献   

8.
污水处理最重要的部分是生物处理,是一种人工增氧的方法。其目的是使曝气池好氧流程中的氧含量达到可接受的范围。本文提出的精确曝气控制系统能够满足DO精确控制的要求,以曝气流量为控制目标。  相似文献   

9.
反应器培养Vero细胞以微载体(Cytodex等载体)及NBS公司CellGen310酯片培养为主,培养工艺对设备、技术要求高,一次性投资大,微载体和酯片处理繁琐,耗材价格昂贵,生产成本高.实验采用一次性激流-灌注式生物反应器大规模培养Vero细胞,通过控制DO、pH等条件,开发出便捷、稳定的大规模培养工艺,为疫苗工业采用大规模细胞培养工艺生产疫苗奠定基础.  相似文献   

10.
生物人工肝体外支持系统供氧问题的研究   总被引:1,自引:0,他引:1  
生物人工肝支持系统是目前肝病治疗领域的重要研究课题。而其中的供氧问题直接关系着肝细胞的培养和活性维持,有着重要的研究意义。本文在建立了分体式生物反应器氧循环模型的基础上。通过差分方程的方法求解计算,得出溶液的溶氧浓度的具体分布。并通过对结果的讨论,分析了罐子中溶液的溶氧浓度随时间的变化趋势。  相似文献   

11.
An engineering system may consist of several different types of components,belonging to such physical"domains"as mechanical,electrical,fluid,and thermal.It is t...  相似文献   

12.
The intersection of Quantum Technologies and Robotics Autonomy is explored in the present paper.The two areas are brought together in establishing an interdisci...  相似文献   

13.
黑棣  郑美茹 《机电工程》2016,(11):1315-1321
针对具有进油孔的有限长滑动轴承油膜力求解问题,采用变分原理和分离变量法,求得了有限长滑动轴承油膜压力分布的近似解析表达式。将油膜压力分布的近似解析表达式在油膜存在区域上进行积分,即得到了油膜力。将提出的计算有限长滑动轴承油膜力方法与无限长轴承模型、有限元方法的计算结果进行了比较,发现了提出的方法与有限元方法的计算结果很接近。最后,研究了进油孔位置和进油压力对油膜存在区域、油膜力等的影响,研究结果表明进油孔位置和进油压力对油膜存在区域和油膜力有较大的影响。  相似文献   

14.
The strength of composite plate with different hole-shapes is always one of the most important but complicated issues in the application of the composite material. The holes will lead to mutations and discontinuity to the structure. So the hole-edge stress concentration is always a serious phenomenon. And the phenomenon makes the structure strength decrease very quickly to form dangerous weak points. Most partial damage begins from these weak points. According to the complex variable functions theory, the accurate boundary condition of composite plate with different hole-shapes is founded by conformal mapping method to settle the boundary condition problem of complex hole-shapes. Composite plate with commonly hole-shapes in engineering is studied by several complex variable stress fimction. The boundary integral equations are founded based on exact boundary conditions. Then the exact hole-edge stress analytic solution of composite plate with rectangle holes and wing manholes is resolved. Both of offset axis loadings and its influences on the stress concentration coefficient of the hole-edge are discussed. And comparisons of different loads along various offset axis on the hole-edge stress distribution of orthotropic plate with rectangle hole or wing manhole are made. It can be concluded that hole-edge with continuous variable curvatures might help to decrease the stress concentration coefficient; and smaller angle of outer load and fiber can decrease the stress peak value.  相似文献   

15.
马立新  王宏宇 《机电工程》2015,32(1):118-122
针对传统的电力系统多目标粒子群优化算法采用权重系数法将多目标转化为单目标,从而忽视了各目标函数间的竞争关系这一问题,提出将非支配解提取法运用到电力系统多目标无功优化中,并设定了一套提取规则,以电力系统中的有功网损、电压偏差和电压稳定裕度为目标,使目标在充分竞争的情况下得出Pareto最优解,利用IEEE-14节点系统对多目标非支配解提取法的电力系统无功优化进行了仿真测试。研究结果表明,该算法一次运行可以得出多组非支配解,既有偏向单个目标的解也有兼顾所有目标的解,克服了权重系数法的盲目性和单一性,可使电力决策者根据实际问题选择最优解,具有较好的灵活性与多样性。  相似文献   

16.
The use of hand gestures can be the most intuitive human-machine interaction medium.The early approaches for hand gesture recognition used device-based methods....  相似文献   

17.
The fraction defective of semi-finished products is predicted to optimize the process of relay production lines, by which production quality and productivity ar...  相似文献   

18.
A graph as the new engineering method for estimate the safety of bulging deformation of coke tower is proposed. Through stresses analysis of circumferential weld of coke tower and comparing the stresses produced by pressure with heat stress of steady state, residual stress, bending stress produced by both itself weight and wind loads, it showed that the stresses produced by pressure on the angle distortion are the main factor of equivalent stress of the combined stress. After comparing four kinds of stress controlling conditions, the relation to stress with depth of angular distortion, grade of curvature of angular distortion and half of region of angular distortion has been inferred. Graph of deformation allowable value of coke tower for different condition by angular distortion and half of region of angular distortion has been plotted. The five steps for its engineering use have been explained. The lighter the grade of curvature is, the larger of bulge allowance, may be, and the bigger of depth of angular distortion may pose too. For the coke tower with a popular structure of Dg 5 400 mm×28 mm, the result by graph is nearly more than the result of two formulas formed by other research, the error is less than 7.0%. But, the graph can be easily applied to different size of angular distortion.  相似文献   

19.
This article describes designing, implementation and tuning processes of multiple-tapped-delay-line (MTDL). Obtained MTDL can be implemented in various field-programmable-logic-devices (FPGA) devices and applied for time-to-digital-converters (TDC) construction. The task of tuning process is the tapped-delay-line (TDL) linearisation, and consists of two stages. The first stage depends on selecting an appropriate configurable-logic-block (CLB) for particular delay-segment realization and selecting proper connection between these blocks. The second tuning stage, that is essential from this article viewpoint, depends on inter CLBs connecting wires delay regulation realized directly by load regulation. The Load regulation depends on connecting an appropriate number of unused three-state-buffers or CLB inputs to the wire which delay is adjusted. Depending on the number of inputs connected to the wire its capacitance changes that influences its time-constant and finally changes its time-delay.The MTDL mathematical model, obtained characteristics and results of time-interval (TI) measurements are also presented. The derived TDL model provides information about how the particular wire delay should be changed and in which order the changes should be executed. This makes the designing process predictable and easy to carry out. Presented characteristics confirm the proper operation of presented linearisation technique. The proper operation of the whole measuring module is confirmed by obtained TIs histograms presentation.  相似文献   

20.
针对实际电网存在着大量的三绕组变压器,但国际上一些著名商业软件,如BPA仿真软件、Matpower这一权威潮流计算开源软件,均只提供双绕组变压器模型,限制了其在具有三绕组变压器的电力系统中的应用的问题,潮流计算是自主开发的电力系统各种应用软件的核心模块,因此依托国际权威开源程序进行二次开发,是一种较好的选择。对Matpower要求的数据格式进行了归纳,对变压器的一般的等值电路及带理想变压器的等值电路和带标幺值的等值电路进行了分析研究,提出了三绕组变压器转换为双绕组等效模型的建模方法,使得原先只适应双绕组变压器的潮流计算软件可以适用于三绕组变压器电网的潮流计算;最后以Matpower软件为例进行了案例计算,并用PSASP仿真软件进行对比验证。研究结果证明,所提出的建模方法是有效的。  相似文献   

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