N-丁基-6-乙氧基喹哪啶半方酸菁的合成与表征

以4-乙氧基苯胺、巴豆醛和方酸等为原料,通过Skraup-Doebner-Von Miller、成盐、缩合等多步反应,以较高产率合成出了合成了一种半方酸菁功能染料,并利用FT-IR、1H NMR对其结构进行表征。这种半方酸菁可以用于合成不对称方酸菁染料,用于太阳能电池、生物探针、光动力学治疗等领域。     

水溶性吲哚菁染料的合成、光谱性能及其应用

设计、合成了3种水溶性吲哚菁染料(发射波长:690 nm),用核磁共振波谱(NMR)对其进行了表征,测试了菁染料在不同溶剂中的紫外吸收光谱和荧光发射光谱;为了探讨菁染料在生物分析领域的应用性,测定3种菁染料在十六烷基三甲基溴化铵(CTAB)和十二烷基磺酸钠(SDS)两种表面活性剂胶束模拟的生理条件下的吸收和发射光谱,利用循环伏安法(CV)测定了菁染料的光稳定性,在近红外区域观察了染料对肾癌细胞的活细胞染色性能,并计算了3种菁染料的摩尔吸光系数和荧光量子产率。     

水溶性吲哚菁染料的合成、光谱性能及其应用的研究

设计、合成了3种水溶性吲哚菁染料（发射波长：690 nm）,用核磁共振（NMR）对其进行了表征,测试了菁染料在不同溶剂中的紫外吸收光谱和荧光发射光谱;为了探讨菁染料在生物分析领域的应用性,测定3种菁染料在十六烷基三甲基溴化铵（CTAB）和十二烷基磺酸钠（SDS）两种表面活性剂胶束模拟的生理条件下的吸收和发射光谱,利用循环伏安法（CV）测定了菁染料的光稳定性,在近红外区域观察了染料对肾癌细胞的活细胞染色性能,并计算了3种菁染料的摩尔吸光系数和荧光量子产率。     

菁染料的研究进展

菁染料以其特有的结构,已成为在光谱增感、光盘存储、生物分析、太阳能电池、无机离子和的测量等方面应用广泛的功能材料之一。本文综述了近几年的研究情况,简单介绍了菁染料的相关知识,和它在合成方面的进展,以及在以上几个方面的应用情况。     

近红外吲哚碳菁染料及应用

近红外甲川链吲哚碳菁染料以其特有的结构,而具有多种功能和用途,已成为在光盘、太阳能电池、照相感光、生物分析等方面应用最为的染料品种之一。探讨了2,3,3－三甲基－3H－吲哚甲川链类菁染料的结构、合成及性能等,综述了其在上述领域中取得的重大应用进展,提出了其中所存在的问题。     

C．A．染料文摘（144：23、24、25、26；145：1）

144：434452e 苯并吲哚菁染料的合成和应用Fan，Fangli等Huaxue Tongbao 2005，68（9），w102／1W102／10（中文） 这是一篇评述文章。苯并吲哚菁染料已成为最重要的染料之一，它通过其光谱结构和性能已被用于光碟，照相和生物分析。本文就苯并吲哚菁染料的合成与应用的发展作些介绍，并就其发展的前景作了预测。     

四碳连接臂水溶性吲哚方酸双菁染料的合成及性能

以苯肼和对肼基苯磺酸为原料合成了一种水溶性对称吲哚方酸双菁染料。最终染料用C-18反相柱进行分离提纯,通过核磁共振氢谱对染料结构进行了表征,测试其在不同溶剂中的紫外-可见吸收和荧光发射光谱。结果发现所合成双菁染料的吸收和发射光谱范围以及Stokes位移、摩尔消光系数与单菁染料相比没有大的变化,荧光量子产率小于单菁染料。     

菁染料在荧光探针及光动力疗法中的应用

菁染料的研究及应用已有100多年的历史，近年来，它们在生物方面的应用研究已取得一定的成果．本就近几年菁染料及其衍生物在生物医疗方面的研究及进展情况加以综述，特别阐述了这类染料用作荧光探针在生物大分子标识以及作为光敏剂在光动力疗法(PDT)中用于恶性肿瘤的诊断与治疗这两方面的研究进展．     

菁染料在生物医学中的应用研究进展

菁染料的研究已有100多年的历史,目前其应用主要集中在非线性光学材料、光谱增感剂、光盘存储材料等方面。随着科学技术的发展,各学科的交叉和融合以及人们对菁染料性质的深入认识,菁染料已被应用于核酸及蛋白质分析测定、大分子标记、肿瘤检测、癌细胞识别、光动力疗法等方面。主要就2000年以来菁染料在生物医学方面的应用作一简单综述。     

生物标示用3H-吲哚菁染料

随着生物技术和荧光标示技术的飞速发展,3H-吲哚菁染料已成为在DNA、蛋白质及核酸等分析检测中使用的主要荧光探针。其中代表性化合物Cy3.、Cy5.作为新一代商品化荧光标示剂在生物芯片、分子信标等方面得到了重要应用。本文综述了该类碳菁染料在生物领域中取得的重大应用进展、并探讨了其结构与性能之间的关系。     

荧光免疫分析用染料及其研究进展

介绍了染料在荧光免疫分析中的应用原理及所用的荧光染料的研究进展。并且提出了近红外吸收染料在这一领域的应用前景。     

双羟基七甲川菁染料的合成及其光谱性能研究

通过分子设计,分别以2,3,3-三甲基吲哚和1,1,2-三甲基-1H-苯并[e]吲哚为原料,首先合成两种季铵盐,再分别同2-氯-1-甲酰-3-羟基亚甲基环己烯缩合,利用Suzuki-Miyaura反应实现染料中位C—C偶联,以超过70%的收率制备了4种带有活性羟基的七甲川菁染料。利用核磁和高分辨率质谱对染料结构进行了表征。以乙醇为溶剂,用紫外-可见光谱仪考察了染料的光谱性能。采用电流为13.4 A的高压氙灯为光源,考察了染料的光稳定性。探究了pH对染料颜色的影响,并尝试推论变色机理。结果表明,4种七甲川菁染料均在近红外区产生较强吸收,在无水乙醇中均具有良好的光稳定性。不同pH下,染料的光谱性能研究发现,七甲川菁染料吸收光谱受pH影响较大,在pH=5～7时,染料在近红外区有最佳吸收。     

The Chromatography and Identification of Dyes

Meetings of the Hudders field Region, held at Hudders field College of Technology, Hudders field, on 26 March 1968, Mr G. England in the chair; and of the Manchester Junior Section, held at Manchester University Institute of Science and Technology, on 14 November 1968, Mr H. R. Had field in the chair Techniques suitable for the identification of dyes—paper and thin-layer chromatography, ultraviolet and infrared absorption spectro-photometry and electrophoresis—are reviewed. The application of these techniques to equalising and milling acid dyes, food dyes, 1:2 metal-complex dyes, disperse dyes, and fluorescent brightening agents is discussed. Methods of extracting dyes from fibrous substrates are reviewed.     

Improvement of the dyeing and fastness properties of a naphthalimide fluorescent dye using poly(amidoamine) dendrimer

In this study, 4‐amino‐9‐methoxypropylnaphthalimide fluorescent dye (dye 1 ) was reacted with poly(amidoamine) dendrimer G = ?0.5 to prepare a naphthalimide–dendrimer hybrid dye (dye 2 ). The chemical structures of the synthesised dyes were confirmed by elemental analysis, Fourier transform infrared spectroscopy, ¹H nuclear magnetic resonance spectroscopy, and ultraviolet‐visible spectroscopy. The solvatochromism of the dyes was evaluated in various solvents with respect to visible absorption properties, and positive solvatochromism was observed by solvent polarity change from chloroform to ethanol. The dyeing ability of the synthesised dyes was investigated by their application onto nylon fabric, and nylon substrates dyed with dye 2 exhibited marked enhancement both in terms of colour strength and general fastness properties. The results of this study clearly demonstrated the high potential and performance of dye 2 as a novel promising fluorescent dye as compared with dye 1 . Overall, it was inferred that the modification of the naphthalimide fluorescent dye with poly(amidoamine) denderimer could markedly improve the dyeing and fastness properties of the naphthalimide fluorescent dye on nylon fabrics.     

Synthesis of a novel fluorescent coloured copolymer based on 4‐butylthio‐1,8‐naphthalimide

A novel fluorescent coloured copolymer based on naphthalimide was prepared. Acenaphthene was brominated and oxidised to prepare 4‐bromo‐1,8‐naphthalic anhydride and further reacted with butanethiol, 2‐aminoethanol and acryloyl chloride, in order to obtain a new polymerisable fluorescent dye. The synthesised dyes were characterised by differential scanning calorimetry, absorption spectroscopy (Fourier Transform–infrared, proton and carbon nuclear magnetic resonance, ultraviolet–visible spectroscopy) and fluorimetry. Molar extinction coefficients and wavelength maxima were obtained by examining the dye solution in ethanol. The solvatochromic effects of the prepared dyes have also been investigated. Finally, the dye was copolymerised with methyl methacrylate and an intrinsically coloured copolymer was obtained. The photophysical characteristics of the obtained copolymer have also been considered. It is assumed that 99% of the copolymerised dye is chemically bonded to polymer chains. The fluorescent characteristics of the copolymer in the solid state were determined by fluorometer and it was found that it has relatively high fluorescent intensity. The physical properties of the synthesised copolymer have been evaluated by differential scanning calorimetry and gel permeation chromatography.     

氮杂氟硼荧(Aza-BODIPY)染料的研究进展

Aza-BODIPY荧光染料是一种新型荧光化合物,因其突出的优点而得到广泛地应用。从其应用的三方面(光动力学疗法的光敏剂、可控制的荧光传感器、近红外区域的荧光探针)详细描述了Aza-BODIPY荧光染料的研究进展,展望了该领域的研究发展方向。     

On the application of theoretical methods for the prediction of fluorescence maxima of organic dyes

Theoretical methods, especially the well established Pariser-Parr-Pople molecular orbital method, have proved to be very useful in colour prediction of organic dye molecules. Because of the increasing importance of highly fluorescent substances for applications as optical brighteners as well as laser dyes there exists a clear need for a theoretical model which allows the prediction of fluorescence maxima with comparable accuracy to that of absorption maxima. It is shown that the simulation of the change of molecular geometry upon excitation by a simple iterative procedure within the framework of the PPP-method can be used for the calculation of fluorescence maxima with satisfactory accuracy thus allowing reliable predictions for this class of dyes. Therefore the method discussed may prove very helpful in practical and synthetic work on fluorescent organic dyes.     

香豆素类染料的荧光光谱性能及应用性能研究

研究了9只香豆素类荧光染料(Ⅰ-Ⅶ)的光谱性能和应用性能。香豆素类荧光染料在5’-位有取代基可使最大可见吸收波长和荧光发射波长产生红移;当共轭双键长度增加,可使染料颜色变深(V:544,VI:552)。这9只染料用于涤纶染色有很好的应用性能,差别不大;嗯唑环结构(Ⅰ、Ⅱ、Ⅲ)和喹唑酮结构(Ⅵ)的染料耐光牢度明显好于噻唑环结构(Ⅴ)和咪唑环结构(Ⅶ)的染料。     

Fluorescence and kubelka-munk theory

An expression is derived for the spectral radiance factor of a thick sample of material which scatters and absorbs light, and to which has been added a fluorescent dye. It is also shown how to work backwards, calculating absorption and emission spectra of the dye from measurements on dyed and undyed samples. This theory has practical application in colorant formulation, and examples using up to three dyes to colour paper are discussed.