Monoclonal antibodies ICO-02 to blast cell antigens in patients with chronic myeloleukemia in blast crisis

Mice were immunized with blood cells of a patient with chronic granulocytic leukemia, and their cells were subsequently used for the preparation of hybridoma ICO-02. This hybridoma is continuously producing monoclonal antibodies which reacted with cells in 4 out of 13 patients with blastic crisis of chronic granulocytic leukemia and in 6 out of 38 patients with acute lymphoblastic leukemia. Antibodies reacted with blast cells in 2 out of 3 patients with undifferentiated blastic crisis of chronic myelocytic leukemia and in 2 out of 5 patients with lymphoid variant of blastic crisis of chronic granulocytic leukemia. Cells of 6 patients with acute lymphoblastic leukemia which reacted with the monoclonal antibodies had immunological markers of T lymphocytes bone-marrow precursors. Monoclonal antibodies did not react with cells of blood and bone marrow from healthy people and from patients with chronic lymphocytic leukemia, acute myeloblastic leukemia, acute myelomonocytic leukemia, acute monoblastic leukemia and lymphosarcoma.     

不同地形激光雷达数据点云的信息提取方法

针对不同地形点云数据采用不同的滤波和格网插值方法提取地面信息,得到了良好的滤波插值效果,为后续地表下沉盆地获取等工作提供了优质的基础数据。对于不同的点云数据,文中分别进行了针对性的处理。对地表平坦且植被稀少的点云数据,采取高程最低点采样并替代格网高程值的方法;对地物和植被杂乱的点云数据,采用基于先验高程信息滤波与Kriging格网插值相结合的方法;而对于地形起伏较大的点云数据则采用渐点加密TIN滤波与Kriging格网插值相结合的方法,最终得到高质量的基础数据并应用于工程实际。     

Experiments on transverse mode locking of circular cylindrical optical beams and certain flat beams

Transverse mode locking of the Laguerre forms with proper magnitudes and phases in an optical beam with circular cylindrical symmetry can produce a beam with time-varying spot size and intensity. The effect is demonstrated by locking two modes of the cylindrically symmetric set, TEM00qand TEM10qof an He-Ne 6328-Å laser with relative amplitudes 1 and 0.6, respectively. Verification of the time-varying spot was by sampling of the beam with an iris moved about the beam at constant radius. The shape and phase of the detected pulses agreed with predictions for the mode-locked beam. For a flat strip beam, the rectangular TEM00q, TEM20q, and TEM40qmodes were locked with relative amplitudes 1, 0.5, and 0.3, respectively. A beam with time-varying width resulted and was sampled with a slit.     

ICO-10 monoclonal antibodies to the Thy-1 antigen

Mouse monoclonal antibodies (MAB) ICO-10 to Thy-1 antigen were obtained. MAB ICO-10 reacted in indirect immunofluorescence test with 5.7 +/- 0.8% human thymocytes. Antibodies did not react with granulocytes, monocytes, T- and non-T cells from peripheral blood, and with marrow cells of healthy donors. MAB ICO-10 reacted with blast cells from 25 of 53 patients with T-cell acute lymphoblastic leukemia (ALL), from 2 of 5 patients with B-cell ALL. This antigen was absent on blood and marrow cells from some patients with ALL, 80 patients with chronic lymphoid leukemia, 54 patients with chronic granulocytic leukemia at the stage of blastic crisis, 128 patients with acute nonlymphoblastic leukemia. Antibodies are specifically bound to thymocytes and spleen cells of Thy 1.1 and Thy 1.2 mice. MAB ICO-10 detect Thy-1 antigen expressed on human hematopoietic cells. MAB ICO-10 may be applied for human leukemia and lymphoma immune diagnosis.     

IPv6特色应用分析

虽然IPv6较IPv4有诸多优势．但是如果IPv6支持的应用仅仅是IPv4网络上的那些应用．那么向IPv6过渡的动力将会很小。实际上．除了支持IPv4上的应用之外．IPv6非常适合于拥有巨大数量各种细小设备的网络而不是由价格昂贵的计算机组成的网络，这些简单设备不仅仅是手机和呼机．还可以是RFID、家庭网络、网络视频监控，等等。探讨了目前可以预见的IPv6特色应用，如IPv6与RFID，IPv6与家庭网络、IPv6与三重服务、IPv6与移动、IPv6与VoIP、IPv6与WiFi和WiMax、IPv6与信息家电、IPv6与P2P游戏等。     

SWFA: a new buffer management mechanism for TCP over ATM-GFR

We investigate packet discarding schemes for transport control protocol (TCP) over asynchronous transfer mode with guaranteed frame rate service. In this letter, we propose the selective weighted fair allocation (SWFA) scheme, which discards packets from selected sessions. 15 TCP connections with equal minimum cell rate (MCR) and unequal MCRs are simulated. The SWFA scheme with per-virtual connection (VC) queuing is compared with early packet discard (EPD) with first-in, first-out queuing, EPD with per-VC queuing, and differential fair buffer allocation with per-VC queuing. Our results show that SWFA with per-VC queuing achieves significant enhancement on throughputs, goodputs, and fairness.     

YAG激光诱导放电通道伏安特性研究

研究了在空气、油膜和绝缘树脂薄膜这三种放电介质中的伏安特性,得出了在同一介质中,通道电极间电压不随其它初始条件改变而变化,只与放电介质对通道箍缩能力成正比,在本实验中薄膜的通道电压最高80.4V,空气中最低26.0V。通道中电流波形与放电介质有关,同样的高低压组合、相同放电脉宽下在空气和油膜中为矩形波,而在薄膜中为三角波,峰值电流变化不大。电流波形不随脉宽的改变而变化,当增大初始高压端或低压端输入时,电流随之增加,并且低压端输入对提高峰值电流更有效果。     

发射极空气桥InGaP/GaAs HBT的DC和RF特性分析

为抑制电流增益崩塌,提高HBT的热稳定性,研制了发射极空气桥互连结构的HBT晶体管,应用ICCAP提取参数建立VBIC模型,结合模型参数对三种不同结构HBT的DC和RF特性进行比较分析.与引线爬坡互连结构相比,发射极空气桥互连结构HBT的热阻得到改善,热稳定性提高;与发射极电阻镇流方式相比,发射极空气桥HBT的截止频率(fT)相同,最大振荡频率(fmax)提高,最大稳定功率增益(MSG)高出约5dB.     

Optimal binary communication with nonequal probabilities

Optimal signal energies are derived for optimal binary digital communication systems with arbitrary signal probabilities and correlation with both coherent and noncoherent detection. The resulting bit-error probability (BEP) is computed and compared with the BEP of the same systems with equal signal energies. One of the conclusions is that for the coherent system with nonnegative correlation, and for the noncoherent system with arbitrary correlation, the optimal signals are on-off keying (OOK), i.e., the signal with probability p/spl les/0.5 has energy E/p, while the second signal has zero energy, where E is the average signal energy. The proposed system is also better than a system with source coding and equiprobable signals.     

数字图像拼接篡改盲取证技术研究

研究图像的篡改识别问题,由于数字图像能够被轻易的篡改并且很难发现改动痕迹,对篡改像素不融合现象识别不清,导致图像篡改很难被肉眼识别。为解决上述问题,从篡改者的角度对目前流行的篡改手段做了新的分类,详细分析了各种篡改取证技术的优缺点。提出了一种基于统计特征分类的盲检测算法,实验表明,从图像的双谱幅值和相角检测可以准确识别出篡改后的图像,为篡改图像的识别提供了依据。     

成年女性错[牙合]畸形患者颅颌面软硬结构关系的研究

目的：研究成年女性错[牙合]畸形患者软组织侧貌特征与颅颌面骨骼及牙齿的相关性,找出对软组织侧貌影响明显的骨性或牙性畸形。材料与方法：收集120例成年女性错[牙合]畸形患者（年龄18岁-26岁,平均年龄23．5岁）治疗前头颅侧位片,利用Delaire头影测量分析方法测量颅颌面骨骼结构异常程度及鼻唇颏部侧貌软组织突度及相关...     

改进的参考独立分量分析算法

针对参考独立分量分析收敛速度较慢的问题,提出了两种基于改进的快速收敛牛顿迭代方法的参考独立分量分析方法。该方法首先对观测信号进行白化预处理,避免观测信号矩阵求逆运算,减少了算法的计算量;然后采用修正的具有三阶收敛速度的牛顿迭代方法对参考独立分量分析的代价函数进行优化,推导出快速收敛的参考独立分量分析算法。仿真实验结果表明,改进后的算法是有效的,算法收敛速度相对原算法提高了1.7倍,相对现有算法提高了1倍,而且误差更小。     

1.55 mu m multiquantum-well lasers with record performance obtained by atmospheric pressure MOVPE using organometallic phosphorus precursor

The recently available precursor biphosphinoethane (BPE) was used, alongside with phosphine and with tertbutylphosphine (TBP), to grow advanced multiquantum-well (MQW) laser wafers with five quaternary, compressive strained wells. The lowest threshold current densities and the lowest optical losses were obtained with BPE. In particular, the lowest threshold current density, 328 A/cm/sup 2/, is a record among published values for lasers with five wells. In this comparison, the wafer grown with phosphine came a close second and that grown with TBP was third.<>     

On non-blocking multi-stage switching networks with rearrangement or repacking

This paper deals with recent results on non-blocking multi-stage switching networks with rearrangement or repacking and with simultaneous or sequential reswitching. Networks with rearrangement and simultaneous reswitching are considered in some detail. For networks with repacking and simultaneous reswitching, an efficient structure is suggested. For networks with rearrangement or repacking and sequential reswitching suitable configurations are presented. In addition to structure aspects, reswitching methods and crosspoint requirements are also considered.     

CO-2激光治疗尖锐湿疣201例

目的:观察单纯CO2激光治疗女性、男性生殖器和男性肛周尖锐湿疣的疗效。方法:女性尖锐湿疣91例,肛周巨大湿疣10例,均作局部浸润麻醉。男性尖锐湿疣100例作阴茎根部阻滞麻醉。以输出功率5~10W的CO2激光烧灼,使病损组织凝固、碳化、气化。结果:91例女性生殖器尖锐湿疣患者,一次治愈率为41%,10例男性肛周巨大湿疣者,一次治愈率为40%。100例男性生殖器尖锐湿疣患者,一次治愈率为84%。     

Efficient visual object detection with spatially global Gaussian mixture models and uncertainties

In this paper, we deal with the problem of visual detection of moving objects using innovative Gaussian mixture models (GMM). The proposed method, the Spatially Global Gaussian Mixture Model (SGGMM) uses RGB and pixel uncertainty for background modelling. The SGGMM with colours only is used for scenes with moderate illumination changes. When combined with pixel uncertainty statistics, the method can deal efficiently with dynamic backgrounds and scene backgrounds with fast change in luminosity. Experimental evaluation in indoor and outdoor environments shows the performance of the foreground segmentation with the proposed SGGMM model using solely RGB colour or in combination with pixel uncertainties. These experimental scenarios take into account changes in the background within the scene. They are also used to compare the proposed technique with other state-of-the-art segmentation approaches in terms of accuracy and execution time performance. Further, our solution is implemented and tested in embedded camera sensor network nodes.     

CKDⅣ—Ⅴ期的2型糖尿病患者的临床特征分析

目的：探讨GKDⅣ-Ⅴ期的2型糖尿病患者的临床特点。方法：回顾性分析了67例Ⅳ-Ⅴ期的2型糖尿病患者的临床表现,血常规、肝、肾功并根据肾功计算有效肾小球滤过率（eGFR）,及B型超声检查肾脏大小。结果：①CKD第1Ⅴ期与Ⅴ期2型糖尿病患者两者盆血程度夫显著性差异（P〉0.05）。②不同程度水肿的患者间比较,CKDⅣ-Ⅴ期的2型糖尿病患者其血清Alb水平无显著性差异（P〉0.05）,但水肿越重的患者,其心衰的发生率越高（P〈0.05）。③全部CKD Ⅳ-Ⅴ期的2型糖尿病患者肾脏大小正常者占80.60＆,但其血肌酐466.26±277,80μmol/L,而肾脏缩小者仅占19.40%。④全部CKD Ⅳ-Ⅴ期的2型糖尿病继发糖尿病慢性并发症如糖尿病视网膜病变41例（61.19%）,糖尿病周围神经病变22例（32.84%）,合并高血压58例（86.57%）,脑血管意外10例（14.93%）,心血管疾病56例（83.58%）,感染42例（62.69%）。结论：CKD Ⅳ-Ⅴ期的2型糖尿病患者贫血和水肿较重,而大部分患者肾脏体积不缩小。此外,CKD Ⅳ-Ⅴ期的2型糖尿病患者心脑血管并发症、及感染的发生率明显增多,可能是影响患者预后的重要因素。     

1．3μmDH-SLD的性能与工作电流和温度的关系

全面地测试并分析了掩埋双异质结型超辐射激光二极管模块的输出光功率、光谱和消光比与注入电流及温度的变化关系。得到：DH—SLD显示了软阈值特性，其输出光功率随注入电流的增大而增加，随管芯温度的升高而降低。温度不变时，当注入电流小于110mA(约)时，峰值波长随注入电流的增大而减小，当注入电流大于110mA(约)时，峰值波长随注入电流的增大有所增大；峰值波长随温度升高而增大。3dB带宽随注入电流的增大而减小，随温度的升高而略有增大。消光比随注入电流和温度的升高而变化。     

Isolated-utterance speech recognition using hidden Markov modelswith bounded state durations

Hidden Markov models (HMMs) with bounded state durations (HMM/BSD) are proposed to explicitly model the state durations of HMMs and more accurately consider the temporal structures existing in speech signals in a simple, direct, but effective way. A series of experiments have been conducted for speaker dependent applications using 408 highly confusing first-tone Mandarin syllables as the example vocabulary. It was found that in the discrete case the recognition rate of HMM/BSD (78.5%) is 9.0%, 6.3%, and 1.9% higher than the conventional HMMs and HMMs with Poisson and gamma distribution state durations, respectively. In the continuous case (partitioned Gaussian mixture modeling), the recognition rates of HMM/BSD (88.3% with 1 mixture, 88.8% with 3 mixtures, and 89.4% with 5 mixtures) are 6.3%, 5.0%, and 5.5% higher than those of the conventional HMMs, and 5.9% (with 1 mixture), 3.9% (with 3 mixtures) and 3.1% (with 1 mixture), 1.8% (with 3 mixtures) higher than HMMs with Poisson and gamma distributed state durations, respectively     

Photorefractive optics in three-dimensional digital memory

To exceed the capacity limitation of the surface-recording method of current optical data storage, the third dimension is introduced with photorefractive materials. Photorefractive materials are suitable for three-dimensional data storage in conjunction with nonlinear optical systems such as the two-photon absorption process of the material for recording and the confocal laser-scanning system for reading. I will describe the systems and the materials for three-dimensional digital memory with the experimental results for read-only memory with photopolymer, erasable memory with a lithium niobate crystal and rewritable memory with photochromic organic materials. The comparison between photorefractive digital three-dimensional memory with conventional holographic three-dimensional memory and near-field memory is also discussed in terms of dynamic range, noise, recording density, and accessibility